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Page 1
Showing results for pavel strand
Search for Pavel Stierand instead (1 results)
Recombinant Strains of Oncolytic Vaccinia Virus for Cancer Immunotherapy.
Shakiba Y, Vorobyev PO, Mahmoud M, Hamad A, Kochetkov DV, Yusubalieva GM, Baklaushev VP, Chumakov PM, Lipatova AV. Shakiba Y, et al. Biochemistry (Mosc). 2023 Jun;88(6):823-841. doi: 10.1134/S000629792306010X. Biochemistry (Mosc). 2023. PMID: 37748878 Review.
Vaccinia virus (VV) is a member of the Poxviridae, a family of enveloped viruses with a large linear double-stranded DNA genome. The proven safety of the VV strains as well as considerable transgene capacity of the viral genome, make VV an excellent platform for creating r …
Vaccinia virus (VV) is a member of the Poxviridae, a family of enveloped viruses with a large linear double-stranded DNA genome. The …
Emetine blocks DNA replication via proteosynthesis inhibition not by targeting Okazaki fragments.
Lukac D, Machacova Z, Moudry P. Lukac D, et al. Life Sci Alliance. 2022 Sep 9;5(12):e202201560. doi: 10.26508/lsa.202201560. Life Sci Alliance. 2022. PMID: 36260751 Free PMC article.
DNA synthesis of the leading and lagging strands works independently and cells tolerate single-stranded DNA generated during strand uncoupling if it is protected by RPA molecules. ...Here, by analysis of lagging strand synthesis inhibitors, we show tha …
DNA synthesis of the leading and lagging strands works independently and cells tolerate single-stranded DNA generated during …
Solid-Phase Synthesis of Phosphorothioate/Phosphonothioate and Phosphoramidate/Phosphonamidate Oligonucleotides.
Kostov O, Liboska R, Páv O, Novák P, Rosenberg I. Kostov O, et al. Molecules. 2019 May 15;24(10):1872. doi: 10.3390/molecules24101872. Molecules. 2019. PMID: 31096640 Free PMC article.
The H-phosphonate coupling followed by oxidation after each cycle enabled us to successfully combine H-phosphonate and phosphoramidite chemistries to synthesize diversely modified oligonucleotide strands....
The H-phosphonate coupling followed by oxidation after each cycle enabled us to successfully combine H-phosphonate and phosphoramidite chemi …
Resveratrol-Inspired Benzo[b]selenophenes Act as Anti-Oxidants in Yeast.
Mániková D, Šestáková Z, Rendeková J, Vlasáková D, Lukáčová P, Paegle E, Arsenyan P, Chovanec M. Mániková D, et al. Molecules. 2018 Feb 24;23(2):507. doi: 10.3390/molecules23020507. Molecules. 2018. PMID: 29495287 Free PMC article.
We show that some benzo[b]selenophenes can kill yeast cells and that the killing effects are not mediated by DNA damage types that can be detected as DNA double-strand breaks. These benzo[b]selenophenes could potentially be used as anti-fungal agents, although their concen …
We show that some benzo[b]selenophenes can kill yeast cells and that the killing effects are not mediated by DNA damage types that can be de …
Enterovirus particles expel capsid pentamers to enable genome release.
Buchta D, Füzik T, Hrebík D, Levdansky Y, Sukeník L, Mukhamedova L, Moravcová J, Vácha R, Plevka P. Buchta D, et al. Nat Commun. 2019 Mar 8;10(1):1138. doi: 10.1038/s41467-019-09132-x. Nat Commun. 2019. PMID: 30850609 Free PMC article.
The opening in the capsid, which is more than 120 A in diameter, enables the release of the genome without the need to unwind its putative double-stranded RNA segments. We also detect capsids lacking pentamers during genome release from echovirus 30. ...
The opening in the capsid, which is more than 120 A in diameter, enables the release of the genome without the need to unwind its putative d …
Pyrosequencing on a glass surface.
Almeida AV, Manz A, Neužil P. Almeida AV, et al. Lab Chip. 2016 Mar 21;16(6):1063-71. doi: 10.1039/c6lc00114a. Epub 2016 Feb 24. Lab Chip. 2016. PMID: 26907694
These droplets served as reaction "stations" performing pyrosequencing as well as washing stations. The resequencing protocol with 34-mer single-stranded DNA (ssDNA) was used to determine the reaction performance. ...
These droplets served as reaction "stations" performing pyrosequencing as well as washing stations. The resequencing protocol with 34-mer si …
Structure and mechanism of DNA delivery of a gene transfer agent.
Bárdy P, Füzik T, Hrebík D, Pantůček R, Thomas Beatty J, Plevka P. Bárdy P, et al. Nat Commun. 2020 Jun 15;11(1):3034. doi: 10.1038/s41467-020-16669-9. Nat Commun. 2020. PMID: 32541663 Free PMC article.
The structure of RcGTA resembles that of a tailed phage, but it has an oblate head shortened in the direction of the tail axis, which limits its packaging capacity to less than 4,500 base pairs of linear double-stranded DNA. The tail channel of RcGTA contains a trimer of p …
The structure of RcGTA resembles that of a tailed phage, but it has an oblate head shortened in the direction of the tail axis, which limits …
Structures of L-BC virus and its open particle provide insight into Totivirus capsid assembly.
Grybchuk D, Procházková M, Füzik T, Konovalovas A, Serva S, Yurchenko V, Plevka P. Grybchuk D, et al. Commun Biol. 2022 Aug 20;5(1):847. doi: 10.1038/s42003-022-03793-z. Commun Biol. 2022. PMID: 35986212 Free PMC article.
Furthermore, the open particles may be assembly intermediates that are prepared for the incorporation of the virus (+) strand RNA....
Furthermore, the open particles may be assembly intermediates that are prepared for the incorporation of the virus (+) strand RNA....
Virion Structure of Israeli Acute Bee Paralysis Virus.
Mullapudi E, Přidal A, Pálková L, de Miranda JR, Plevka P. Mullapudi E, et al. J Virol. 2016 Aug 26;90(18):8150-9. doi: 10.1128/JVI.00854-16. Print 2016 Sep 15. J Virol. 2016. PMID: 27384649 Free PMC article.
IAPV has major capsid proteins VP1 and VP3 with noncanonical jellyroll beta-barrel folds composed of only seven instead of eight beta-strands, as is the rule for proteins of other viruses with the same fold. ...
IAPV has major capsid proteins VP1 and VP3 with noncanonical jellyroll beta-barrel folds composed of only seven instead of eight beta-str …
37 results