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iPSC-derived cells lack immune tolerance to autologous NK-cells due to imbalance in ligands for activating and inhibitory NK-cell receptors.
Bogomiakova ME, Sekretova EK, Anufrieva KS, Khabarova PO, Kazakova AN, Bobrovsky PA, Grigoryeva TV, Eremeev AV, Lebedeva OS, Bogomazova AN, Lagarkova MA. Bogomiakova ME, et al. Among authors: bobrovsky pa. Stem Cell Res Ther. 2023 Apr 11;14(1):77. doi: 10.1186/s13287-023-03308-5. Stem Cell Res Ther. 2023. PMID: 37038186 Free PMC article.
New anticoagulant protein from medicinal leech.
Manuvera VA, Kharlampieva DD, Bobrovsky PA, Grafskaia EN, Brovina KA, Lazarev VN. Manuvera VA, et al. Among authors: bobrovsky pa. Biochem Biophys Res Commun. 2024 Feb 12;696:149473. doi: 10.1016/j.bbrc.2024.149473. Epub 2024 Jan 12. Biochem Biophys Res Commun. 2024. PMID: 38241814
Dual Adeno-Associated Virus 9 with Codon-Optimized DYSF Gene Promotes In Vivo Muscle Regeneration and May Decrease Inflammatory Response in Limb Girdle Muscular Dystrophy Type R2.
Yakovlev IA, Emelin AM, Slesarenko YS, Limaev IS, Vetrova IA, Belikova LD, Grafskaia EN, Bobrovsky PA, Pokrovsky MV, Kuzubova EV, Pokrovsky VM, Lebedev PA, Bardakov SN, Isaev AA, Deev RV. Yakovlev IA, et al. Among authors: bobrovsky pa. Int J Mol Sci. 2023 Aug 31;24(17):13551. doi: 10.3390/ijms241713551. Int J Mol Sci. 2023. PMID: 37686363 Free PMC article.
Structural insights into thrombolytic activity of destabilase from medicinal leech.
Marin E, Kornilov DA, Bukhdruker SS, Aleksenko VA, Manuvera VA, Zinovev EV, Kovalev KV, Shevtsov MB, Talyzina AA, Bobrovsky PA, Kuzmichev PK, Mishin AV, Gushchin IY, Lazarev VN, Borshchevskiy VI. Marin E, et al. Among authors: bobrovsky pa. Sci Rep. 2023 Apr 24;13(1):6641. doi: 10.1038/s41598-023-32459-x. Sci Rep. 2023. PMID: 37095116 Free PMC article.
Nucleoside Analogs and Perylene Derivatives Modulate Phase Separation of SARS-CoV-2 N Protein and Genomic RNA In Vitro.
Svetlova J, Knizhnik E, Manuvera V, Severov V, Shirokov D, Grafskaia E, Bobrovsky P, Matyugina E, Khandazhinskaya A, Kozlovskaya L, Miropolskaya N, Aralov A, Khodarovich Y, Tsvetkov V, Kochetkov S, Lazarev V, Varizhuk A. Svetlova J, et al. Among authors: bobrovsky p. Int J Mol Sci. 2022 Dec 3;23(23):15281. doi: 10.3390/ijms232315281. Int J Mol Sci. 2022. PMID: 36499608 Free PMC article.
Manifestation of Huntington's disease pathology in human induced pluripotent stem cell-derived neurons.
Nekrasov ED, Vigont VA, Klyushnikov SA, Lebedeva OS, Vassina EM, Bogomazova AN, Chestkov IV, Semashko TA, Kiseleva E, Suldina LA, Bobrovsky PA, Zimina OA, Ryazantseva MA, Skopin AY, Illarioshkin SN, Kaznacheyeva EV, Lagarkova MA, Kiselev SL. Nekrasov ED, et al. Among authors: bobrovsky pa. Mol Neurodegener. 2016 Apr 14;11:27. doi: 10.1186/s13024-016-0092-5. Mol Neurodegener. 2016. PMID: 27080129 Free PMC article.