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High-Dose Acetaminophen with Concurrent CYP2E1 Inhibition Has Profound Anticancer Activity without Liver Toxicity.
J Pharmacol Exp Ther. 2024 Jan 2;388(1):209-217. doi: 10.1124/jpet.123.001772.
J Pharmacol Exp Ther. 2024.
PMID: 37918853
Free PMC article.
High dose acetaminophen inhibits STAT3 and has free radical independent anti-cancer stem cell activity.
Pingali P, Wu YJ, Boothello R, Sharon C, Li H, Sistla S, Sankaranarayanan NV, Desai UR, Le AT, Doebele RC, Muldoon LL, Patel BB, Neuwelt A.
Pingali P, et al.
Neoplasia. 2021 Mar;23(3):348-359. doi: 10.1016/j.neo.2021.02.001. Epub 2021 Feb 26.
Neoplasia. 2021.
PMID: 33640759
Free PMC article.
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High-Dose Acetaminophen with N-acetylcysteine Rescue Inhibits M2 Polarization of Tumor-Associated Macrophages.
Bryan A, Pingali P, Joslyn M, Li H, Bernas T, Koblinski J, Landry J, Lee WS, Patel B, Neuwelt A.
Bryan A, et al. Among authors: pingali p.
Cancers (Basel). 2023 Sep 28;15(19):4770. doi: 10.3390/cancers15194770.
Cancers (Basel). 2023.
PMID: 37835464
Free PMC article.
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