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Page 1
Rivaroxaban in Patients with Atrial Fibrillation and a Bioprosthetic Mitral Valve.
Guimarães HP, Lopes RD, de Barros E Silva PGM, Liporace IL, Sampaio RO, Tarasoutchi F, Hoffmann-Filho CR, de Lemos Soares Patriota R, Leiria TLL, Lamprea D, Precoma DB, Atik FA, Silveira FS, Farias FR, Barreto DO, Almeida AP, Zilli AC, de Souza Neto JD, Cavalcante MA, Figueira FAMS, Kojima FCS, Damiani L, Santos RHN, Valeis N, Campos VB, Saraiva JFK, Fonseca FH, Pinto IM, Magalhães CC, Ferreira JFM, Alexander JH, Pavanello R, Cavalcanti AB, Berwanger O; RIVER Trial Investigators. Guimarães HP, et al. N Engl J Med. 2020 Nov 26;383(22):2117-2126. doi: 10.1056/NEJMoa2029603. Epub 2020 Nov 14. N Engl J Med. 2020. PMID: 33196155 Clinical Trial.
A primary-outcome event occurred at a mean of 347.5 days in the rivaroxaban group and 340.1 days in the warfarin group (difference calculated as restricted mean survival time, 7.4 days; 95% confidence interval [CI], -1.4 to 16.3; P<0.001 for noninferiority). Death from …
A primary-outcome event occurred at a mean of 347.5 days in the rivaroxaban group and 340.1 days in the warfarin group (difference calculate …
Screening tool development for hand surgery referrals in systemic sclerosis.
Marcatto de Abreu MF, Landim S, Yuamoto FY, Lins C, Magalhães EP, Etchebehere M. Marcatto de Abreu MF, et al. Clinics (Sao Paulo). 2023 Aug 17;78:100270. doi: 10.1016/j.clinsp.2023.100270. eCollection 2023. Clinics (Sao Paulo). 2023. PMID: 37597472 Free PMC article.

The surgical group had higher scores on the HAQ-DI (1.39 vs. 0.96, p = 0.032) and CHFS (25.0 vs. 12.0, p = 0.005) questionnaires, and a higher frequency of DU (91.43% vs. 18.75%, p < 0.0010), calcinosis (60.0% vs. 0.0%, p < 0.001), use of vasodil

…
The surgical group had higher scores on the HAQ-DI (1.39 vs. 0.96, p = 0.032) and CHFS (25.0 vs. 12.0, p = 0.005) questionnair …
Resuscitation fluid practices in Brazilian intensive care units: a secondary analysis of Fluid-TRIPS.
Freitas FGR, Hammond N, Li Y, Azevedo LCP, Cavalcanti AB, Taniguchi L, Gobatto A, Japiassú AM, Bafi AT, Mazza BF, Noritomi DT, Dal-Pizzol F, Bozza F, Salluh JIF, Westphal GA, Soares M, Assunção MSC, Lisboa T, Lobo SMA, Barbosa AR, Ventura AF, Souza AF, Silva AF, Toledo A, Reis A, Cembranel A, Rea Neto A, Gut AL, Justo APP, Santos AP, Albuquerque ACD, Scazufka A, Rodrigues AB, Fernandino BB, Silva BG, Vidal BS, Pinheiro BV, Pinto BVC, Feijo CAR, Abreu Filho C, Bosso CEDCN, Moreira CEN, Ramos CHF, Tavares C, Arantes C, Grion C, Mendes CL, Kmohan C, Piras C, Castro CPP, Lins C, Beraldo D, Fontes D, Boni D, Castiglioni D, Paisani DM, Pedroso DFF, Mattos ER, Brito Sobrinho E, Troncoso EMV, Rodrigues Filho EM, Nogueira EEF, Ferreira EL, Pacheco ES, Jodar E, Ferreira ELA, Araujo FF, Trevisol FS, Amorim FF, Giannini FP, Santos FPM, Buarque F, Lima FG, Costa FAAD, Sad FCDA, Aranha FG, Ganem F, Callil F, Costa Filho FF, Dall Arto FTC, Moreno G, Friedman G, Moralez GM, Silva GAD, Costa G, Cavalcanti GS, Cavalcanti GS, Betônico GN, Betônico GN, Reis H, Araujo HBN, Hortiz Júnior HA, Guimaraes HP, Urbano H, Maia I, Santiago Filho IL, Farhat Júnior J, Alvarez JR, Passos JT, Paranhos JEDR, Marque… See abstract for full author list ➔ Freitas FGR, et al. Rev Bras Ter Intensiva. 2021 Apr-Jun;33(2):206-218. doi: 10.5935/0103-507X.20210028. Rev Bras Ter Intensiva. 2021. PMID: 34231801 Free PMC article.

RESULTS: On the study day, 3,214 patients in Brazil and 3,493 patients in other countries were included, of whom 16.1% and 26.8% (p < 0.001) received fluids, respectively. The main indication for fluid resuscitation was impaired perfusion and/or low cardiac output (Braz

…
RESULTS: On the study day, 3,214 patients in Brazil and 3,493 patients in other countries were included, of whom 16.1% and 26.8% (p & …
Single-Nucleotide Variants in the AIM2 - Absent in Melanoma 2 Gene (rs1103577) Associated With Protection for Tuberculosis.
Figueira MBA, de Lima DS, Boechat AL, Filho MGDN, Antunes IA, Matsuda JDS, Ribeiro TRA, Felix LS, Gonçalves ASF, da Costa AG, Ramasawmy R, Pontillo A, Ogusku MM, Sadahiro A. Figueira MBA, et al. Front Immunol. 2021 Apr 1;12:604975. doi: 10.3389/fimmu.2021.604975. eCollection 2021. Front Immunol. 2021. PMID: 33868225 Free PMC article.
NLRP3/AIM2 mediate the release of pro-inflammatory cytokines IL-1beta and IL-18 to control M. tuberculosis infection. Variants of genes involved in inflammasomes may contribute to elucidation of host immune responses to TB infection. ...Serum IL-1beta concentrations were h …
NLRP3/AIM2 mediate the release of pro-inflammatory cytokines IL-1beta and IL-18 to control M. tuberculosis infection. Variants of gen …
The impact of obesity in hospitalized patients with COVID-19: a retrospective cohort study.
Carra FA, de Melo ME, Stumpf MAM, Cercato C, Fernandes AE, Mancini MC; EPICCoV Study Group. Carra FA, et al. Diabetol Metab Syndr. 2024 Jan 19;16(1):20. doi: 10.1186/s13098-023-01246-z. Diabetol Metab Syndr. 2024. PMID: 38238775 Free PMC article.
The mean age was 60.3 years, 56.2% were men, 65.2% were white and the mean BMI was 28.1 kg/m(2). SAPS-3 score was a risk factor for all patient-centered outcomes (HR 1.032 for mortality, OR 1.03 for dialysis, OR 1.07 for vasoactive drug use, and OR 1.08 for intubation, …
The mean age was 60.3 years, 56.2% were men, 65.2% were white and the mean BMI was 28.1 kg/m(2). SAPS-3 score was a risk factor for a …
Flagellar apparatus of south-seeking many-celled magnetotactic prokaryotes.
Silva KT, Abreu F, Almeida FP, Keim CN, Farina M, Lins U. Silva KT, et al. Microsc Res Tech. 2007 Jan;70(1):10-7. doi: 10.1002/jemt.20380. Microsc Res Tech. 2007. PMID: 17019700
The flagella were helical tubes never as long as a complete turn of the helix. Flagellar filaments varied in length from 0.9 to 3.8 micro m (average 2.4 +/- 0.5 micro m, n = 150) and in width from 12.0 to 19.5 nm (average 15.9 +/- 1.4 nm, n = 52), which is different …
The flagella were helical tubes never as long as a complete turn of the helix. Flagellar filaments varied in length from 0.9 to 3.8 micro …
Intranasal Liposomal Formulation of Spike Protein Adjuvanted with CpG Protects and Boosts Heterologous Immunity of hACE2 Transgenic Mice to SARS-CoV-2 Infection.
Russo M, Mendes-Corrêa MC, Lins BB, Kersten V, Pernambuco Filho PCA, Martins TR, Tozetto-Mendoza TR, Vilas Boas LS, Gomes BM, Dati LMM, Duarte-Neto AN, Reigado GR, Frederico ABT, de Brito E Cunha DRA, de Paula AV, da Silva JIG, Vasconcelos CFM, Chambergo FS, Nunes VA, Ano Bom APD, Castilho LR, Martins RAP, Hirata MH, Mirotti L. Russo M, et al. Vaccines (Basel). 2023 Nov 20;11(11):1732. doi: 10.3390/vaccines11111732. Vaccines (Basel). 2023. PMID: 38006064 Free PMC article.
Long-term treatment of familial male-limited precocious puberty (testotoxicosis) with cyproterone acetate or ketoconazole.
Almeida MQ, Brito VN, Lins TS, Guerra-Junior G, de Castro M, Antonini SR, Arnhold IJ, Mendonca BB, Latronico AC. Almeida MQ, et al. Clin Endocrinol (Oxf). 2008 Jul;69(1):93-8. doi: 10.1111/j.1365-2265.2007.03160.x. Epub 2008 Jul 1. Clin Endocrinol (Oxf). 2008. PMID: 18088394
PATIENTS: Ten boys from eight unrelated Brazilian families who carried known LH-receptor activating mutations were treated with 70 mg/m(2) cyproterone acetate (n = 5) or 10 mg/kg ketoconazole (n = 5) for a mean period of 5 and 8 years, respectively. ...RESULTS: Growth velo …
PATIENTS: Ten boys from eight unrelated Brazilian families who carried known LH-receptor activating mutations were treated with 70 mg/m …
Higher central fat and poor self-body image in short-stature overweight/obese women living in Brazilian shantytowns.
Bueno NB, Florêncio TT, Cavalcante FA, Lins IL, Clemente AG, Sawaya AL. Bueno NB, et al. PeerJ. 2016 Oct 6;4:e2547. doi: 10.7717/peerj.2547. eCollection 2016. PeerJ. 2016. PMID: 27761335 Free PMC article.
RESULTS: The SS group showed a higher waist-to-height ratio (WHtR) (mean: 0.63; standard deviation: 0.06 for SS and mean: 0.60; standard deviation: 0.07 for the NS group; p = 0.02), and, in the adjusted analysis, showed lower fat-free mass (Estimated Marginal Mean for the …
RESULTS: The SS group showed a higher waist-to-height ratio (WHtR) (mean: 0.63; standard deviation: 0.06 for SS and mean: 0.60; standard dev …