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Page 1
Identification of a Potent Cytotoxic Pyrazole with Anti-Breast Cancer Activity That Alters Multiple Pathways.
Cells. 2022 Jan 12;11(2):254. doi: 10.3390/cells11020254.
Cells. 2022.
PMID: 35053370
Free PMC article.
Identification of a Unique Cytotoxic Thieno[2,3-c]Pyrazole Derivative with Potent and Selective Anticancer Effects In Vitro.
Hess JD, Macias LH, Gutierrez DA, Moran-Santibanez K, Contreras L, Medina S, Villanueva PJ, Kirken RA, Varela-Ramirez A, Penichet ML, Aguilera RJ.
Hess JD, et al. Among authors: villanueva pj.
Biology (Basel). 2022 Jun 18;11(6):930. doi: 10.3390/biology11060930.
Biology (Basel). 2022.
PMID: 35741451
Free PMC article.
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The Antimalarial Drug Pyronaridine Inhibits Topoisomerase II in Breast Cancer Cells and Hinders Tumor Progression In Vivo.
Villanueva PJ, Gutierrez DA, Contreras L, Parra K, Segura-Cabrera A, Varela-Ramirez A, Aguilera RJ.
Villanueva PJ, et al.
Clin Cancer Drugs. 2021 Mar;8(1):50-56. doi: 10.2174/2212697x08666210219101023. Epub 2021 Feb 19.
Clin Cancer Drugs. 2021.
PMID: 35178342
Free PMC article.
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Pyronaridine exerts potent cytotoxicity on human breast and hematological cancer cells through induction of apoptosis.
Villanueva PJ, Martinez A, Baca ST, DeJesus RE, Larragoity M, Contreras L, Gutierrez DA, Varela-Ramirez A, Aguilera RJ.
Villanueva PJ, et al.
PLoS One. 2018 Nov 5;13(11):e0206467. doi: 10.1371/journal.pone.0206467. eCollection 2018.
PLoS One. 2018.
PMID: 30395606
Free PMC article.
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A new pyridazinone exhibits potent cytotoxicity on human cancer cells via apoptosis and poly-ubiquitinated protein accumulation.
Gutierrez DA, DeJesus RE, Contreras L, Rodriguez-Palomares IA, Villanueva PJ, Balderrama KS, Monterroza L, Larragoity M, Varela-Ramirez A, Aguilera RJ.
Gutierrez DA, et al. Among authors: villanueva pj.
Cell Biol Toxicol. 2019 Dec;35(6):503-519. doi: 10.1007/s10565-019-09466-8. Epub 2019 Mar 1.
Cell Biol Toxicol. 2019.
PMID: 30825052
Free PMC article.
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