Paul J. M. Wijnker - Search Results

Year	Number of Results
2011	2
2012	3
2013	4
2014	3
2015	2
2016	2
2017	1
2018	3
2019	3
2020	1
2021	2
2022	1
2024	1

1

S-glutathiolation impairs phosphoregulation and function of cardiac myosin-binding protein C in human heart failure.

Stathopoulou K, Wittig I, Heidler J, Piasecki A, Richter F, Diering S, van der Velden J, Buck F, Donzelli S, Schröder E, Wijnker PJ, Voigt N, Dobrev D, Sadayappan S, Eschenhagen T, Carrier L, Eaton P, Cuello F. Stathopoulou K, et al. Among authors: wijnker pj. FASEB J. 2016 May;30(5):1849-64. doi: 10.1096/fj.201500048. Epub 2016 Feb 2. FASEB J. 2016. PMID: 26839380 Free PMC article.

2

Low expression of the K280N TNNT2 mutation is sufficient to increase basal myofilament activation in human hypertrophy cardiomyopathy.

Sequeira V, Wang L, Wijnker PJM, Kim K, Pinto JR, Dos Remedios C, Redwood C, Knollmann BC, van der Velden J. Sequeira V, et al. Among authors: wijnker pjm. J Mol Cell Cardiol Plus. 2022 Sep;1:100007. doi: 10.1016/j.jmccpl.2022.100007. J Mol Cell Cardiol Plus. 2022. PMID: 37159677 Free PMC article.

3

Translational investigation of electrophysiology in hypertrophic cardiomyopathy.

Flenner F, Jungen C, Küpker N, Ibel A, Kruse M, Koivumäki JT, Rinas A, Zech ATL, Rhoden A, Wijnker PJM, Lemoine MD, Steenpass A, Girdauskas E, Eschenhagen T, Meyer C, van der Velden J, Patten-Hamel M, Christ T, Carrier L. Flenner F, et al. Among authors: wijnker pjm. J Mol Cell Cardiol. 2021 Aug;157:77-89. doi: 10.1016/j.yjmcc.2021.04.009. Epub 2021 May 3. J Mol Cell Cardiol. 2021. PMID: 33957110 Free PMC article.

4

Hypertrophic cardiomyopathy dysfunction mimicked in human engineered heart tissue and improved by sodium-glucose cotransporter 2 inhibitors.

Wijnker PJM, Dinani R, van der Laan NC, Algül S, Knollmann BC, Verkerk AO, Remme CA, Zuurbier CJ, Kuster DWD, van der Velden J. Wijnker PJM, et al. Cardiovasc Res. 2024 Mar 14;120(3):301-317. doi: 10.1093/cvr/cvae004. Cardiovasc Res. 2024. PMID: 38240646 Free PMC article.

5

Hypertrophic Cardiomyopathy: A Vicious Cycle Triggered by Sarcomere Mutations and Secondary Disease Hits.

Wijnker PJM, Sequeira V, Kuster DWD, Velden JV. Wijnker PJM, et al. Antioxid Redox Signal. 2019 Aug 1;31(4):318-358. doi: 10.1089/ars.2017.7236. Epub 2018 Apr 11. Antioxid Redox Signal. 2019. PMID: 29490477 Free PMC article. Review.

6

Mutation-specific pathology and treatment of hypertrophic cardiomyopathy in patients, mouse models and human engineered heart tissue.

Wijnker PJM, van der Velden J. Wijnker PJM, et al. Biochim Biophys Acta Mol Basis Dis. 2020 Aug 1;1866(8):165774. doi: 10.1016/j.bbadis.2020.165774. Epub 2020 Mar 23. Biochim Biophys Acta Mol Basis Dis. 2020. PMID: 32217077 Free article. Review.

7

Development of a 3-Dimensional Model to Study Right Heart Dysfunction in Pulmonary Arterial Hypertension: First Observations.

Llucià-Valldeperas A, Smal R, Bekedam FT, Cé M, Pan X, Manz XD, Wijnker PJM, Vonk-Noordegraaf A, Bogaard HJ, Goumans MJ, Man FS. Llucià-Valldeperas A, et al. Among authors: wijnker pjm. Cells. 2021 Dec 20;10(12):3595. doi: 10.3390/cells10123595. Cells. 2021. PMID: 34944102 Free PMC article.

8

ADP-stimulated contraction: A predictor of thin-filament activation in cardiac disease.

Sequeira V, Najafi A, Wijnker PJ, Dos Remedios CG, Michels M, Kuster DW, van der Velden J. Sequeira V, et al. Among authors: wijnker pj. Proc Natl Acad Sci U S A. 2015 Dec 15;112(50):E7003-12. doi: 10.1073/pnas.1513843112. Epub 2015 Nov 30. Proc Natl Acad Sci U S A. 2015. PMID: 26621701 Free PMC article.

9

The homozygous K280N troponin T mutation alters cross-bridge kinetics and energetics in human HCM.

Piroddi N, Witjas-Paalberends ER, Ferrara C, Ferrantini C, Vitale G, Scellini B, Wijnker PJM, Sequiera V, Dooijes D, Dos Remedios C, Schlossarek S, Leung MC, Messer A, Ward DG, Biggeri A, Tesi C, Carrier L, Redwood CS, Marston SB, van der Velden J, Poggesi C. Piroddi N, et al. Among authors: wijnker pjm. J Gen Physiol. 2019 Jan 7;151(1):18-29. doi: 10.1085/jgp.201812160. Epub 2018 Dec 21. J Gen Physiol. 2019. PMID: 30578328 Free PMC article.

10

Phosphomimetic cardiac myosin-binding protein C partially rescues a cardiomyopathy phenotype in murine engineered heart tissue.

Dutsch A, Wijnker PJM, Schlossarek S, Friedrich FW, Krämer E, Braren I, Hirt MN, Brenière-Letuffe D, Rhoden A, Mannhardt I, Eschenhagen T, Carrier L, Mearini G. Dutsch A, et al. Among authors: wijnker pjm. Sci Rep. 2019 Dec 3;9(1):18152. doi: 10.1038/s41598-019-54665-2. Sci Rep. 2019. PMID: 31796859 Free PMC article.

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