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Page 1
SLC5A1 Variants in Turkish Patients with Congenital Glucose-Galactose Malabsorption.
Genes (Basel). 2023 Jun 27;14(7):1359. doi: 10.3390/genes14071359.
Genes (Basel). 2023.
PMID: 37510265
Free PMC article.
Identification of aryl sulfonamides as novel and potent inhibitors of NaV1.5.
Sun S, Jia Q, Zenova AY, Lin S, Hussainkhel A, Mezeyova J, Chang E, Goodchild SJ, Xie Z, Lindgren A, de Boer G, Kwan R, Khakh K, Sojo L, Bichler P, Johnson JP Jr, Empfield JR, Cohen CJ, Dehnhardt CM, Dean R.
Sun S, et al. Among authors: bichler p.
Bioorg Med Chem Lett. 2021 Aug 1;45:128133. doi: 10.1016/j.bmcl.2021.128133. Epub 2021 May 24.
Bioorg Med Chem Lett. 2021.
PMID: 34044121
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Discovery of Aryl Sulfonamides as Isoform-Selective Inhibitors of NaV1.7 with Efficacy in Rodent Pain Models.
Focken T, Liu S, Chahal N, Dauphinais M, Grimwood ME, Chowdhury S, Hemeon I, Bichler P, Bogucki D, Waldbrook M, Bankar G, Sojo LE, Young C, Lin S, Shuart N, Kwan R, Pang J, Chang JH, Safina BS, Sutherlin DP, Johnson JP Jr, Dehnhardt CM, Mansour TS, Oballa RM, Cohen CJ, Robinette CL.
Focken T, et al. Among authors: bichler p.
ACS Med Chem Lett. 2016 Jan 19;7(3):277-82. doi: 10.1021/acsmedchemlett.5b00447. eCollection 2016 Mar 10.
ACS Med Chem Lett. 2016.
PMID: 26985315
Free PMC article.
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Design of Conformationally Constrained Acyl Sulfonamide Isosteres: Identification of N-([1,2,4]Triazolo[4,3- a]pyridin-3-yl)methane-sulfonamides as Potent and Selective hNaV1.7 Inhibitors for the Treatment of Pain.
Focken T, Chowdhury S, Zenova A, Grimwood ME, Chabot C, Sheng T, Hemeon I, Decker SM, Wilson M, Bichler P, Jia Q, Sun S, Young C, Lin S, Goodchild SJ, Shuart NG, Chang E, Xie Z, Li B, Khakh K, Bankar G, Waldbrook M, Kwan R, Nelkenbrecher K, Karimi Tari P, Chahal N, Sojo L, Robinette CL, White AD, Chen CA, Zhang Y, Pang J, Chang JH, Hackos DH, Johnson JP Jr, Cohen CJ, Ortwine DF, Sutherlin DP, Dehnhardt CM, Safina BS.
Focken T, et al. Among authors: bichler p.
J Med Chem. 2018 Jun 14;61(11):4810-4831. doi: 10.1021/acs.jmedchem.7b01826. Epub 2018 May 23.
J Med Chem. 2018.
PMID: 29737846
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Mechanistic aspects of alkyne migration in alkylidene carbenoid rearrangements.
Bichler P, Chalifoux WA, Eisler S, Shi Shun AL, Chernick ET, Tykwinski RR.
Bichler P, et al.
Org Lett. 2009 Feb 5;11(3):519-22. doi: 10.1021/ol8023665.
Org Lett. 2009.
PMID: 19128149
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Total Synthesis of K777: Successful Application of Transition-Metal-Catalyzed Alkyne Hydrothiolation toward the Modular Synthesis of a Potent Cysteine Protease Inhibitor.
Kiemele ER, Wathier M, Bichler P, Love JA.
Kiemele ER, et al. Among authors: bichler p.
Org Lett. 2016 Feb 5;18(3):492-5. doi: 10.1021/acs.orglett.5b03535. Epub 2016 Jan 26.
Org Lett. 2016.
PMID: 26811991
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