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Page 1
Discovery of IACS-52825, a Potent and Selective DLK Inhibitor for Treatment of Chemotherapy-Induced Peripheral Neuropathy.
J Med Chem. 2023 Jul 27;66(14):9954-9971. doi: 10.1021/acs.jmedchem.3c00788. Epub 2023 Jul 12.
J Med Chem. 2023.
PMID: 37436942
Inhibition of dual leucine zipper kinase prevents chemotherapy-induced peripheral neuropathy and cognitive impairments.
Ma J, Goodwani S, Acton PJ, Buggia-Prevot V, Kesler SR, Jamal I, Mahant ID, Liu Z, Mseeh F, Roth BL, Chakraborty C, Peng B, Wu Q, Jiang Y, Le K, Soth MJ, Jones P, Kavelaars A, Ray WJ, Heijnen CJ.
Ma J, et al. Among authors: acton pj.
Pain. 2021 Oct 1;162(10):2599-2612. doi: 10.1097/j.pain.0000000000002256.
Pain. 2021.
PMID: 33872235
Free PMC article.
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Dual Leucine Zipper Kinase Is Constitutively Active in the Adult Mouse Brain and Has Both Stress-Induced and Homeostatic Functions.
Goodwani S, Fernandez C, Acton PJ, Buggia-Prevot V, McReynolds ML, Ma J, Hu CH, Hamby ME, Jiang Y, Le K, Soth MJ, Jones P, Ray WJ.
Goodwani S, et al. Among authors: acton pj.
Int J Mol Sci. 2020 Jul 9;21(14):4849. doi: 10.3390/ijms21144849.
Int J Mol Sci. 2020.
PMID: 32659913
Free PMC article.
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Alzheimer's disease-type neuronal tau hyperphosphorylation induced by A beta oligomers.
De Felice FG, Wu D, Lambert MP, Fernandez SJ, Velasco PT, Lacor PN, Bigio EH, Jerecic J, Acton PJ, Shughrue PJ, Chen-Dodson E, Kinney GG, Klein WL.
De Felice FG, et al. Among authors: acton pj.
Neurobiol Aging. 2008 Sep;29(9):1334-47. doi: 10.1016/j.neurobiolaging.2007.02.029. Epub 2007 Apr 2.
Neurobiol Aging. 2008.
PMID: 17403556
Free PMC article.
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