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Page 1
Whole-genome sequencing reveals host factors underlying critical COVID-19.
Kousathanas A, Pairo-Castineira E, Rawlik K, Stuckey A, Odhams CA, Walker S, Russell CD, Malinauskas T, Wu Y, Millar J, Shen X, Elliott KS, Griffiths F, Oosthuyzen W, Morrice K, Keating S, Wang B, Rhodes D, Klaric L, Zechner M, Parkinson N, Siddiq A, Goddard P, Donovan S, Maslove D, Nichol A, Semple MG, Zainy T, Maleady-Crowe F, Todd L, Salehi S, Knight J, Elgar G, Chan G, Arumugam P, Patch C, Rendon A, Bentley D, Kingsley C, Kosmicki JA, Horowitz JE, Baras A, Abecasis GR, Ferreira MAR, Justice A, Mirshahi T, Oetjens M, Rader DJ, Ritchie MD, Verma A, Fowler TA, Shankar-Hari M, Summers C, Hinds C, Horby P, Ling L, McAuley D, Montgomery H, Openshaw PJM, Elliott P, Walsh T, Tenesa A; GenOMICC investigators; 23andMe investigators; COVID-19 Human Genetics Initiative; Fawkes A, Murphy L, Rowan K, Ponting CP, Vitart V, Wilson JF, Yang J, Bretherick AD, Scott RH, Hendry SC, Moutsianas L, Law A, Caulfield MJ, Baillie JK. Kousathanas A, et al. Nature. 2022 Jul;607(7917):97-103. doi: 10.1038/s41586-022-04576-6. Epub 2022 Mar 7. Nature. 2022. PMID: 35255492 Free PMC article.
Baricitinib in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial and updated meta-analysis.
RECOVERY Collaborative Group. RECOVERY Collaborative Group. Lancet. 2022 Jul 30;400(10349):359-368. doi: 10.1016/S0140-6736(22)01109-6. Lancet. 2022. PMID: 35908569 Free PMC article.
At randomisation, 95% of patients were receiving corticosteroids and 23% were receiving tocilizumab (with planned use within the next 24 h recorded for a further 9%). Overall, 514 (12%) of 4148 patients allocated to baricitinib versus 546 (14%) of 4008 patients allocated t …
At randomisation, 95% of patients were receiving corticosteroids and 23% were receiving tocilizumab (with planned use within the next 24 …
Natural climate solutions.
Griscom BW, Adams J, Ellis PW, Houghton RA, Lomax G, Miteva DA, Schlesinger WH, Shoch D, Siikamäki JV, Smith P, Woodbury P, Zganjar C, Blackman A, Campari J, Conant RT, Delgado C, Elias P, Gopalakrishna T, Hamsik MR, Herrero M, Kiesecker J, Landis E, Laestadius L, Leavitt SM, Minnemeyer S, Polasky S, Potapov P, Putz FE, Sanderman J, Silvius M, Wollenberg E, Fargione J. Griscom BW, et al. Proc Natl Acad Sci U S A. 2017 Oct 31;114(44):11645-11650. doi: 10.1073/pnas.1710465114. Epub 2017 Oct 16. Proc Natl Acad Sci U S A. 2017. PMID: 29078344 Free PMC article.
Safety, Immunogenicity, and Efficacy of the NVX-CoV2373 COVID-19 Vaccine in Adolescents: A Randomized Clinical Trial.
Áñez G, Dunkle LM, Gay CL, Kotloff KL, Adelglass JM, Essink B, Campbell JD, Cloney-Clark S, Zhu M, Plested JS, Roychoudhury P, Greninger AL, Patel N, McGarry A, Woo W, Cho I, Glenn GM, Dubovsky F; 2019nCoV-301–Pediatric Expansion Study Group. Áñez G, et al. JAMA Netw Open. 2023 Apr 3;6(4):e239135. doi: 10.1001/jamanetworkopen.2023.9135. JAMA Netw Open. 2023. PMID: 37099299 Free PMC article. Clinical Trial.
Feasibility of Coronary Access Following Redo-TAVR for Evolut Failure: A Computed Tomography Simulation Study.
Tang GHL, Spencer J, Rogers T, Grubb KJ, Gleason P, Gada H, Mahoney P, Dauerman HL, Forrest JK, Reardon MJ, Blanke P, Leipsic JA, Abdel-Wahab M, Attizzani GF, Puri R, Caskey M, Chung CJ, Chen YH, Dudek D, Allen KB, Chhatriwalla AK, Htun WW, Blackman DJ, Tarantini G, Zhingre Sanchez J, Schwartz G, Popma JJ, Sathananthan J. Tang GHL, et al. Circ Cardiovasc Interv. 2023 Nov;16(11):e013238. doi: 10.1161/CIRCINTERVENTIONS.123.013238. Epub 2023 Nov 21. Circ Cardiovasc Interv. 2023. PMID: 37988439 Free PMC article.
Redo Transcatheter Aortic Valve Implantation in the Lotus Mechanically Expanded Transcatheter Heart Valve: Bench-Top Analysis, Clinical Experience, and Procedural Guidance.
Alfadhel M, Frawley C, Sathananthan J, de Backer O, Abdel-Wahab M, Abdelhafez A, Van Mieghem NM, van den Dorpel M, Arunothayaraj S, Hildick-Smith D, Blackman DJ. Alfadhel M, et al. Circ Cardiovasc Interv. 2023 Nov;16(11):e013296. doi: 10.1161/CIRCINTERVENTIONS.123.013296. Epub 2023 Nov 21. Circ Cardiovasc Interv. 2023. PMID: 37988436
Flight Capacity of the Walnut Twig Beetle (Coleoptera: Scolytidae) on a Laboratory Flight Mill.
Kees AM, Hefty AR, Venette RC, Seybold SJ, Aukema BH. Kees AM, et al. Environ Entomol. 2017 Jun 1;46(3):633-641. doi: 10.1093/ee/nvx055. Environ Entomol. 2017. PMID: 28334300
Thousand cankers disease is responsible for the decline of Juglans species throughout the western United States and more recently, the eastern United States and northern Italy. We examined the flight capacity of P. juglandis over 24-h trials on a flight mill in the laborat …
Thousand cankers disease is responsible for the decline of Juglans species throughout the western United States and more recently, the easte …
Trees tolerate an extreme heatwave via sustained transpirational cooling and increased leaf thermal tolerance.
Drake JE, Tjoelker MG, Vårhammar A, Medlyn BE, Reich PB, Leigh A, Pfautsch S, Blackman CJ, López R, Aspinwall MJ, Crous KY, Duursma RA, Kumarathunge D, De Kauwe MG, Jiang M, Nicotra AB, Tissue DT, Choat B, Atkin OK, Barton CVM. Drake JE, et al. Glob Chang Biol. 2018 Jun;24(6):2390-2402. doi: 10.1111/gcb.14037. Epub 2018 Feb 2. Glob Chang Biol. 2018. PMID: 29316093
We withheld irrigation for 1 month to dry the surface soils and then implemented an extreme heatwave treatment of 4 consecutive days with air temperatures exceeding 43C, while monitoring whole-canopy exchange of CO(2) and H(2) O, leaf temperatures, leaf thermal tolerance, …
We withheld irrigation for 1 month to dry the surface soils and then implemented an extreme heatwave treatment of 4 consecutive days with ai …
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