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patrick wobbling
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Patrick Wöbbeking
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Queuine, a tRNA anticodon wobble base, maintains the proliferative and pluripotent potential of HL-60 cells in the presence of the differentiating agent 6-thioguanine.
Proc Natl Acad Sci U S A. 1991 Jan 15;88(2):370-4. doi: 10.1073/pnas.88.2.370.
Proc Natl Acad Sci U S A. 1991.
PMID: 1988936
Free PMC article.
6-Thioguanine (6-TG)-induced differentiation of hypoxanthine phosphoribosyltransferase (IMP: pyrophosphate phosphoribosyltransferase, EC 2.4.2.8)-deficient HL-60 cells is characterized by 2 days of growth, after which morphological differentiation proceeds. Addition of the tRNA …
6-Thioguanine (6-TG)-induced differentiation of hypoxanthine phosphoribosyltransferase (IMP: pyrophosphate phosphoribosyltransferase, EC 2.4 …
Hematopoiesis and the inosine modification in transfer RNA.
Trewyn RW, Kretz KA, Utz ED, Patrick DE, Muralidhar G.
Trewyn RW, et al.
Proc Soc Exp Biol Med. 1985 Sep;179(4):497-503. doi: 10.3181/00379727-179-42129.
Proc Soc Exp Biol Med. 1985.
PMID: 3927306
Human promyelocytic leukemia (HL-60) cells were used to begin to evaluate the role in hematopoiesis of inosine biosynthesis in the tRNA anticodon wobble position; a reaction involving the enzymatic insertion of performed hypoxanthine. ...
Human promyelocytic leukemia (HL-60) cells were used to begin to evaluate the role in hematopoiesis of inosine biosynthesis in the tRNA anti …
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