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Year Number of Results
2010 1
2012 3
2013 4
2014 3
2015 4
2016 3
2017 5
2018 6
2019 7
2020 10
2021 2
2022 10
2023 3
2024 3

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53 results

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Page 1
Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME.
Godoy P, Hewitt NJ, Albrecht U, Andersen ME, Ansari N, Bhattacharya S, Bode JG, Bolleyn J, Borner C, Böttger J, Braeuning A, Budinsky RA, Burkhardt B, Cameron NR, Camussi G, Cho CS, Choi YJ, Craig Rowlands J, Dahmen U, Damm G, Dirsch O, Donato MT, Dong J, Dooley S, Drasdo D, Eakins R, Ferreira KS, Fonsato V, Fraczek J, Gebhardt R, Gibson A, Glanemann M, Goldring CE, Gómez-Lechón MJ, Groothuis GM, Gustavsson L, Guyot C, Hallifax D, Hammad S, Hayward A, Häussinger D, Hellerbrand C, Hewitt P, Hoehme S, Holzhütter HG, Houston JB, Hrach J, Ito K, Jaeschke H, Keitel V, Kelm JM, Kevin Park B, Kordes C, Kullak-Ublick GA, LeCluyse EL, Lu P, Luebke-Wheeler J, Lutz A, Maltman DJ, Matz-Soja M, McMullen P, Merfort I, Messner S, Meyer C, Mwinyi J, Naisbitt DJ, Nussler AK, Olinga P, Pampaloni F, Pi J, Pluta L, Przyborski SA, Ramachandran A, Rogiers V, Rowe C, Schelcher C, Schmich K, Schwarz M, Singh B, Stelzer EH, Stieger B, Stöber R, Sugiyama Y, Tetta C, Thasler WE, Vanhaecke T, Vinken M, Weiss TS, Widera A, Woods CG, Xu JJ, Yarborough KM, Hengstler JG. Godoy P, et al. Among authors: mcmullen p. Arch Toxicol. 2013 Aug;87(8):1315-530. doi: 10.1007/s00204-013-1078-5. Epub 2013 Aug 23. Arch Toxicol. 2013. PMID: 23974980 Free PMC article. Review.
Hidden hydrophobicity impacts polymer immunogenicity.
Yuan Z, McMullen P, Luozhong S, Sarker P, Tang C, Wei T, Jiang S. Yuan Z, et al. Among authors: mcmullen p. Chem Sci. 2023 Jan 30;14(8):2033-2039. doi: 10.1039/d2sc07047b. eCollection 2023 Feb 22. Chem Sci. 2023. PMID: 36845929 Free PMC article.
Considerations for Improving Metabolism Predictions for In Vitro to In Vivo Extrapolation.
Moreau M, Mallick P, Smeltz M, Haider S, Nicolas CI, Pendse SN, Leonard JA, Linakis MW, McMullen PD, Clewell RA, Clewell HJ, Yoon M. Moreau M, et al. Among authors: mcmullen pd. Front Toxicol. 2022 Apr 29;4:894569. doi: 10.3389/ftox.2022.894569. eCollection 2022. Front Toxicol. 2022. PMID: 35573278 Free PMC article. Review.
Developing tools for defining and establishing pathways of toxicity.
Andersen ME, McMullen PD, Krewski D. Andersen ME, et al. Among authors: mcmullen pd. Arch Toxicol. 2015 May;89(5):809-12. doi: 10.1007/s00204-015-1512-y. Epub 2015 Apr 8. Arch Toxicol. 2015. PMID: 25851822 Free PMC article. No abstract available.
The human toxome project.
Bouhifd M, Andersen ME, Baghdikian C, Boekelheide K, Crofton KM, Fornace AJ Jr, Kleensang A, Li H, Livi C, Maertens A, McMullen PD, Rosenberg M, Thomas R, Vantangoli M, Yager JD, Zhao L, Hartung T. Bouhifd M, et al. Among authors: mcmullen pd. ALTEX. 2015;32(2):112-24. doi: 10.14573/altex.1502091. Epub 2015 Mar 4. ALTEX. 2015. PMID: 25742299 Free PMC article.
Applying 'omics technologies in chemicals risk assessment: Report of an ECETOC workshop.
Buesen R, Chorley BN, da Silva Lima B, Daston G, Deferme L, Ebbels T, Gant TW, Goetz A, Greally J, Gribaldo L, Hackermüller J, Hubesch B, Jennen D, Johnson K, Kanno J, Kauffmann HM, Laffont M, McMullen P, Meehan R, Pemberton M, Perdichizzi S, Piersma AH, Sauer UG, Schmidt K, Seitz H, Sumida K, Tollefsen KE, Tong W, Tralau T, van Ravenzwaay B, Weber RJM, Worth A, Yauk C, Poole A. Buesen R, et al. Among authors: mcmullen p. Regul Toxicol Pharmacol. 2017 Dec;91 Suppl 1(Suppl 1):S3-S13. doi: 10.1016/j.yrtph.2017.09.002. Epub 2017 Sep 25. Regul Toxicol Pharmacol. 2017. PMID: 28958911 Free PMC article. Review.
Impacts of a Zwitterionic Peptide on its Fusion Protein.
McMullen P, Fang L, Qiao Q, Shao Q, Jiang S. McMullen P, et al. Bioconjug Chem. 2022 Aug 17;33(8):1485-1493. doi: 10.1021/acs.bioconjchem.2c00176. Epub 2022 Jul 19. Bioconjug Chem. 2022. PMID: 35852436
Extracellular vesicles incorporating retrovirus-like capsids for the enhanced packaging and systemic delivery of mRNA into neurons.
Gu W, Luozhong S, Cai S, Londhe K, Elkasri N, Hawkins R, Yuan Z, Su-Greene K, Yin Y, Cruz M, Chang YW, McMullen P, Wu C, Seo C, Guru A, Gao W, Sarmiento T, Schaffer C, Nishimura N, Cerione R, Yu Q, Warden M, Langer R, Jiang S. Gu W, et al. Among authors: mcmullen p. Nat Biomed Eng. 2024 Feb 19. doi: 10.1038/s41551-023-01150-x. Online ahead of print. Nat Biomed Eng. 2024. PMID: 38374224
A Chromatin-Mimetic Nanomedicine for Therapeutic Tolerance Induction.
Li B, Yuan Z, McMullen P, Xie J, Jain P, Hung HC, Xu S, Zhang P, Lin X, Wu K, Jiang S. Li B, et al. Among authors: mcmullen p. ACS Nano. 2018 Dec 26;12(12):12004-12014. doi: 10.1021/acsnano.8b04314. Epub 2018 Nov 16. ACS Nano. 2018. PMID: 30412375
53 results