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Pathophysiology of heart failure.
Schwinger RHG. Schwinger RHG. Cardiovasc Diagn Ther. 2021 Feb;11(1):263-276. doi: 10.21037/cdt-20-302. Cardiovasc Diagn Ther. 2021. PMID: 33708498 Free PMC article. Review.
Interventional and surgical therapy options may be performed as well. The understanding of the underlying pathophysiology of heart failure is essential to initiate the adequate therapeutic option individually for each patient. ...
Interventional and surgical therapy options may be performed as well. The understanding of the underlying pathophysiology of heart fa …
Idiopathic subglottic stenosis: a review.
Aravena C, Almeida FA, Mukhopadhyay S, Ghosh S, Lorenz RR, Murthy SC, Mehta AC. Aravena C, et al. J Thorac Dis. 2020 Mar;12(3):1100-1111. doi: 10.21037/jtd.2019.11.43. J Thorac Dis. 2020. PMID: 32274178 Free PMC article. Review.
Therapeutic endoscopic procedures and surgery are the most common management modalities, but medical therapy can also play a significant role in preventing or delaying recurrence. In this review, we describe the morphology, pathophysiology, clinical presentation, evaluatio …
Therapeutic endoscopic procedures and surgery are the most common management modalities, but medical therapy can also play a significant rol …
Serological diagnosis of myasthenia gravis and its clinical significance.
Li Y, Peng Y, Yang H. Li Y, et al. Ann Transl Med. 2023 Apr 15;11(7):290. doi: 10.21037/atm-19-363. Epub 2019 Sep 29. Ann Transl Med. 2023. PMID: 37090043 Free PMC article. Review.
Patients with MG can also have other antibodies, such as anti-titin, anti-ryanodine receptor (anti-RyR), anti-Agrin and anti-KV1.4 antibodies. Since MG is heterogeneous in terms of pathophysiology, antibody status, and other factors, serological tests are crucial for clini …
Patients with MG can also have other antibodies, such as anti-titin, anti-ryanodine receptor (anti-RyR), anti-Agrin and anti-KV1.4 antibodie …
Median arcuate ligament syndrome (Dunbar syndrome).
Iqbal S, Chaudhary M. Iqbal S, et al. Cardiovasc Diagn Ther. 2021 Oct;11(5):1172-1176. doi: 10.21037/cdt-20-846. Cardiovasc Diagn Ther. 2021. PMID: 34815969 Free PMC article. Review.
However, both the diagnosis and therapeutic intervention remains challenging. Extensive evaluation of etiology and pathophysiology of MALS and addressing the same through minimally invasive techniques may yield best prognosis in future. ...
However, both the diagnosis and therapeutic intervention remains challenging. Extensive evaluation of etiology and pathophysiology of …
Obesity in Adults: A 2022 Adapted Clinical Practice Guideline for Ireland.
Breen C, O'Connell J, Geoghegan J, O'Shea D, Birney S, Tully L, Gaynor K, O'Kelly M, O'Malley G, O'Donovan C, Lyons O, Flynn M, Allen S, Arthurs N, Browne S, Byrne M, Callaghan S, Collins C, Courtney A, Crotty M, Donohue C, Donovan C, Dunlevy C, Duggan D, Fearon N, Finucane F, Fitzgerald I, Foy S, Garvey J, Gibson I, Glynn L, Gregg E, Griffin A, Harrington JM, Heary C, Heneghan H, Hogan A, Hynes M, Kearney C, Kelly D, Neff K, le Roux CW, Manning S, McAuliffe F, Moore S, Moran N, Murphy M, Murrin C, O'Brien SM, O'Donnell C, O'Dwyer S, O'Grada C, O'Malley E, O'Reilly O, O'Reilly S, Porter O, Roche HM, Rhynehart A, Ryan L, Seery S, Soare C, Shaamile F, Walsh A, Woods C, Woods C, Yoder R. Breen C, et al. Obes Facts. 2022;15(6):736-752. doi: 10.1159/000527131. Epub 2022 Oct 24. Obes Facts. 2022. PMID: 36279848 Free PMC article. Review.
The guideline reflects substantial advances in the understanding of the determinants, pathophysiology, assessment, and treatment of obesity. SUMMARY: It shifts the focus of obesity management toward improving patient-centred health outcomes, functional outcomes, and social …
The guideline reflects substantial advances in the understanding of the determinants, pathophysiology, assessment, and treatment of o …
Total subaxial reconstruction.
Quadros DG, Guiroy A, Fontes RBV. Quadros DG, et al. J Spine Surg. 2020 Mar;6(1):280-289. doi: 10.21037/jss.2020.03.04. J Spine Surg. 2020. PMID: 32309666 Free PMC article. Review.
While many cases are asymptomatic, some patients may have significant pain and disability. We provide a brief review of the pathophysiology of cervical deformity and the technical aspects of deformity correction in the cervical spine. ...
While many cases are asymptomatic, some patients may have significant pain and disability. We provide a brief review of the pathophysiolo …
Hepatic hydrothorax.
Wilkins H, Britt E, Bhatnagar M, Pippard B. Wilkins H, et al. J Thorac Dis. 2024 Feb 29;16(2):1662-1673. doi: 10.21037/jtd-23-1649. Epub 2024 Feb 23. J Thorac Dis. 2024. PMID: 38505059 Free PMC article. Review.
As such, it is crucial to adopt a multi-disciplinary approach-involving pulmonologists, hepatologists, dieticians, and palliative care physicians-in order to optimise care for this often complex group of patients. This review will discuss the basic pathophysiology of HH, i …
As such, it is crucial to adopt a multi-disciplinary approach-involving pulmonologists, hepatologists, dieticians, and palliative care physi …
In conversation with Peter Macheroux.
Skourti E, Macheroux P. Skourti E, et al. FEBS J. 2023 May;290(9):2208-2213. doi: 10.1111/febs.16646. Epub 2022 Oct 29. FEBS J. 2023. PMID: 36308323
Peter's research spans a diverse selection of topics, and his work has contributed significantly towards advancing our understanding of bacterial enzymology, plant physiology and the molecular pathways that underlie human pathophysiology. Among Peter's many scientific achi …
Peter's research spans a diverse selection of topics, and his work has contributed significantly towards advancing our understanding of bact …
GWAS Meta-Analysis of Suicide Attempt: Identification of 12 Genome-Wide Significant Loci and Implication of Genetic Risks for Specific Health Factors.
Docherty AR, Mullins N, Ashley-Koch AE, Qin X, Coleman JRI, Shabalin A, Kang J, Murnyak B, Wendt F, Adams M, Campos AI, DiBlasi E, Fullerton JM, Kranzler HR, Bakian AV, Monson ET, Rentería ME, Walss-Bass C, Andreassen OA, Behera C, Bulik CM, Edenberg HJ, Kessler RC, Mann JJ, Nurnberger JI Jr, Pistis G, Streit F, Ursano RJ, Polimanti R, Dennis M, Garrett M, Hair L, Harvey P, Hauser ER, Hauser MA, Huffman J, Jacobson D, Madduri R, McMahon B, Oslin DW, Trafton J, Awasthi S, Berrettini WH, Bohus M, Chang X, Chen HC, Chen WJ, Christensen ED, Crow S, Duriez P, Edwards AC, Fernández-Aranda F, Galfalvy H, Gandal M, Gorwood P, Guo Y, Hafferty JD, Hakonarson H, Halmi KA, Hishimoto A, Jain S, Jamain S, Jiménez-Murcia S, Johnson C, Kaplan AS, Kaye WH, Keel PK, Kennedy JL, Kim M, Klump KL, Levey DF, Li D, Liao SC, Lieb K, Lilenfeld L, Marshall CR, Mitchell JE, Okazaki S, Otsuka I, Pinto D, Powers A, Ramoz N, Ripke S, Roepke S, Rozanov V, Scherer SW, Schmahl C, Sokolowski M, Starnawska A, Strober M, Su MH, Thornton LM, Treasure J, Ware EB, Watson HJ, Witt SH, Woodside DB, Yilmaz Z, Zillich L, Adolfsson R, Agartz I, Alda M, Alfredsson L, Appadurai V, Artigas MS, Van der Auwera S, Azevedo MH, Bas… See abstract for full author list ➔ Docherty AR, et al. Am J Psychiatry. 2023 Oct 1;180(10):723-738. doi: 10.1176/appi.ajp.21121266. Am J Psychiatry. 2023. PMID: 37777856 Free PMC article.
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