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In Vitro and Computational Studies of Perezone and Perezone Angelate as Potential Anti-Glioblastoma Multiforme Agents.
Hernández-Rodríguez M, Mendoza Sánchez PI, Martínez J, Macías Pérez ME, Rosales Cruz E, Żołek T, Maciejewska D, Miranda Ruvalcaba R, Mera Jiménez E, Nicolás-Vázquez MI. Hernández-Rodríguez M, et al. Among authors: mendoza sanchez pi. Molecules. 2022 Feb 26;27(5):1565. doi: 10.3390/molecules27051565. Molecules. 2022. PMID: 35268667 Free PMC article.
In vitro and computational studies showed that perezone inhibits PARP-1 and induces changes in the redox state of K562 cells.
Hernández-Rodríguez M, Mendoza Sánchez PI, Macias Perez ME, Rosales Cruz E, Mera Jiménez E, Nicolás Vázquez MI, Miranda Ruvalcaba R. Hernández-Rodríguez M, et al. Among authors: mendoza sanchez pi. Arch Biochem Biophys. 2019 Aug 15;671:225-234. doi: 10.1016/j.abb.2019.05.002. Epub 2019 May 4. Arch Biochem Biophys. 2019. PMID: 31063714
Green Approach Extraction of Perezone from the Roots of Acourtia platyphilla (A. Grey): A Comparison of Four Activating Modes and Supercritical Carbon Dioxide.
Escobedo-González R, Vázquez Cabañas AV, Martínez González A, Mendoza Sánchez P, Saavedra-Leos Z, Cruz-Olivares J, Nava Serrano J, Martínez J, Miranda Ruvalcaba R. Escobedo-González R, et al. Among authors: mendoza sanchez p. Molecules. 2019 Aug 21;24(17):3035. doi: 10.3390/molecules24173035. Molecules. 2019. PMID: 31438606 Free PMC article.