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Page 1
The clinician's guide to randomized trials: interpretation.
Thabane A, Phillips MR, Wong TY, Thabane L, Bhandari M, Chaudhary V; Retina Evidence Trials InterNational Alliance (R.E.T.I.N.A.) Study Group. Thabane A, et al. Eye (Lond). 2022 Mar;36(3):481-482. doi: 10.1038/s41433-021-01866-7. Epub 2022 Jan 21. Eye (Lond). 2022. PMID: 35058599 Free PMC article. No abstract available.
Retinal Optical Coherence Tomography Features Associated With Incident and Prevalent Parkinson Disease.
Wagner SK, Romero-Bascones D, Cortina-Borja M, Williamson DJ, Struyven RR, Zhou Y, Patel S, Weil RS, Antoniades CA, Topol EJ, Korot E, Foster PJ, Balaskas K, Ayala U, Barrenechea M, Gabilondo I, Schapira AHV, Khawaja AP, Patel PJ, Rahi JS, Denniston AK, Petzold A, Keane PA; for UK Biobank Eye & Vision Consortium. Wagner SK, et al. Neurology. 2023 Oct 17;101(16):e1581-e1593. doi: 10.1212/WNL.0000000000207727. Epub 2023 Aug 21. Neurology. 2023. PMID: 37604659 Free PMC article.
Individuals with prevalent PD had thinner GCIPL (-2.12 mum, 95% CI -3.17 to -1.07, p = 8.2 10(-5)) and INL (-0.99 mum, 95% CI -1.52 to -0.47, p = 2.1 10(-4)). ...Thinner GCIPL (hazard ratio [HR] 0.62 per SD increase, 95% CI 0.46-0.84, p = 0.002) and thinner I …
Individuals with prevalent PD had thinner GCIPL (-2.12 mum, 95% CI -3.17 to -1.07, p = 8.2 10(-5)) and INL (-0.99 mum, 95% CI -1.52 t …
Subretinal drusenoid deposits, age-related macular degeneration, and cardiovascular disease.
Smith RT, Olsen TW, Chong V, Kim J, Hammer M, Lema G, Deobhakta A, Tan A, Tong Y, Tai K, Fei Y, Mordechaev E, Ledesma-Gil G, Otero-Marquez O, Rosen RB, Bhuiyan A, Sivaprasad S, Rosenfeld PJ. Smith RT, et al. Asia Pac J Ophthalmol (Phila). 2024 Jan-Feb;13(1):100036. doi: 10.1016/j.apjo.2024.100036. Epub 2024 Jan 19. Asia Pac J Ophthalmol (Phila). 2024. PMID: 38244930 Free article. Review.
Prevalence of diabetic retinopathy in urban and rural India: A systematic review and meta-analysis.
Brar AS, Sahoo J, Behera UC, Jonas JB, Sivaprasad S, Das T. Brar AS, et al. Indian J Ophthalmol. 2022 Jun;70(6):1945-1955. doi: 10.4103/ijo.IJO_2206_21. Indian J Ophthalmol. 2022. PMID: 35647959 Free PMC article. Review.
The prevalence of DR was 17.44% (95% confidence interval [CI], 14.33-20.55) in urban and 14.00% (95% CI: 9.13-18.86) in rural population (P = 0.24). The overall DR prevalence was 16.10% (95% CI: 13.16-24.32), and the population prevalence was 1.63% [95% CI: 0.94-2.32]. ...
The prevalence of DR was 17.44% (95% confidence interval [CI], 14.33-20.55) in urban and 14.00% (95% CI: 9.13-18.86) in rural population ( …
Outcomes of neovascular glaucoma in eyes presenting with moderate to good visual potential.
Rani PK, Sen P, Sahoo NK, Senthil S, Chakurkar R, Anup M, Behera UC, Sivaprasad S, Das T; India Retinal Disease Study Group. Rani PK, et al. Int Ophthalmol. 2021 Jul;41(7):2359-2368. doi: 10.1007/s10792-021-01789-y. Epub 2021 Mar 21. Int Ophthalmol. 2021. PMID: 33745037

The mean number of intravitreal anti-VEGF injections per eye was higher in the Indian cohort (1.65 0.97 versus 1.14 1.02 injections; p < 0.001). The number of eyes with closed angles (36.9% India versus 30.5% UK; p = 0.45) and the number of eyes needing glaucoma

The mean number of intravitreal anti-VEGF injections per eye was higher in the Indian cohort (1.65 0.97 versus 1.14 1.02 injections; p
Discrepancy in current central serous chorioretinopathy classification.
Singh SR, Matet A, van Dijk EHC, Daruich A, Fauser S, Yzer S, Peiretti E, Sivaprasad S, Lotery AJ, Boon CJF, Behar-Cohen F, Freund KB, Chhablani J. Singh SR, et al. Br J Ophthalmol. 2019 Jun;103(6):737-742. doi: 10.1136/bjophthalmol-2018-312435. Epub 2018 Jul 12. Br J Ophthalmol. 2019. PMID: 30002069
The consistency in diagnosing acute CSCR was statistically higher than for either chronic (p=0.012) or recurrent CSCR (p<0.0001). When collapsing descriptors into six main terms, agreement remained poor (Fleiss Kappa=0.218). ...
The consistency in diagnosing acute CSCR was statistically higher than for either chronic (p=0.012) or recurrent CSCR (p<0. …
Incidence and Risk Factors of Visual Impairment in Patients with Angioid Streaks and Macular Neovascularization.
Cicinelli MV, Torrioli E, La Franca L, Agrawal H, Barthelmes D, Chhablani J, Chowers I, Foa N, Goldstein M, Mansour A, Muhammed RP, Sivaprasad S, Vilela MAP, Zweifel S, Bandello F, Battaglia Parodi M. Cicinelli MV, et al. Ophthalmol Retina. 2023 May;7(5):431-440. doi: 10.1016/j.oret.2022.12.002. Epub 2022 Dec 9. Ophthalmol Retina. 2023. PMID: 36503161

The average rate (95% confidence interval [CI]) of visual loss was +0.04 (0.02-0.06) logarithm of the minimum angle of resolution/year (P < 0.001); the visual loss was faster in nonnaive eyes (P = 0.007) and those with better baseline VA (P < 0.001); it

The average rate (95% confidence interval [CI]) of visual loss was +0.04 (0.02-0.06) logarithm of the minimum angle of resolution/year (P
Plasma levels and dietary intake of minerals in patients with type 2 diabetes and chronic kidney disease: A case-control study.
Sivaprasad M, Shalini T, Sahay M, Sahay R, Satyanarayanan M, Reddy GB. Sivaprasad M, et al. J Trace Elem Med Biol. 2024 Jul;84:127425. doi: 10.1016/j.jtemb.2024.127425. Epub 2024 Mar 4. J Trace Elem Med Biol. 2024. PMID: 38484635
RESULTS: The median values of plasma Ca in the DKD group were significantly lower compared with the DNCKD and C groups (10.5 mg/dL vs. 11.0 mg/dL and 11.7 mg/dL, p<0.001). Furthermore, plasma Ca levels lowered with declining kidney function, as evidenced by the eGFR and …
RESULTS: The median values of plasma Ca in the DKD group were significantly lower compared with the DNCKD and C groups (10.5 mg/dL vs. 11.0 …
Is immediate treatment necessary for diabetic macular edema after pars plana vitrectomy for tractional complications of proliferative diabetic retinopathy?
Behera UC, Das T, Sivaprasad S, Rani PK, Raman R, Agarwal M, Agarwal T, Sahu S, Vaidya H, Panchal B; India Retinal Disease Study group. Behera UC, et al. Int Ophthalmol. 2021 Nov;41(11):3607-3614. doi: 10.1007/s10792-021-01923-w. Epub 2021 Jun 25. Int Ophthalmol. 2021. PMID: 34170479

At one year, there was a statistically significant reduction in mean central subfield thickness in treated (467.9 124.8 mum to 367.8 143.7 mum; p < 0.001) as well as observed (405.2 132.6 mum to 325.6 149 mum; p < 0.001) eyes, and the change was comparable (

At one year, there was a statistically significant reduction in mean central subfield thickness in treated (467.9 124.8 mum to 367.8 143.7 m …
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