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Year Number of Results
2006 1
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2012 4
2014 1
2015 4
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2020 3
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2023 1
2024 0

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28 results

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Page 1
House dust mites activate nociceptor-mast cell clusters to drive type 2 skin inflammation.
Serhan N, Basso L, Sibilano R, Petitfils C, Meixiong J, Bonnart C, Reber LL, Marichal T, Starkl P, Cenac N, Dong X, Tsai M, Galli SJ, Gaudenzio N. Serhan N, et al. Nat Immunol. 2019 Nov;20(11):1435-1443. doi: 10.1038/s41590-019-0493-z. Epub 2019 Oct 7. Nat Immunol. 2019. PMID: 31591569 Free PMC article.
Here we found that HDMs with cysteine protease activity directly activated peptidergic nociceptors, which are neuropeptide-producing nociceptive sensory neurons that express the ion channel TRPV1 and Tac1, the gene encoding the precursor for the neuropeptide substance P. I …
Here we found that HDMs with cysteine protease activity directly activated peptidergic nociceptors, which are neuropeptide-producing nocicep …
Mast cell-derived BH4 is a critical mediator of postoperative pain.
Starkl P, Jonsson G, Artner T, Turnes BL, Serhan N, Oliveira T, Gail LM, Stejskal K, Channon KM, Köcher T, Stary G, Klang V, Gaudenzio N, Knapp S, Woolf CJ, Penninger JM, Cronin SJF. Starkl P, et al. bioRxiv [Preprint]. 2023 Jan 24:2023.01.24.525378. doi: 10.1101/2023.01.24.525378. bioRxiv. 2023. PMID: 37293068 Free PMC article. Preprint.
Substance P receptor blockade substantially ameliorated postoperative pain. Our findings underline the unique position of mast cells at the neuro-immune interface and highlight substance P-driven mast cell BH4 production as promising therapeutic targets for the trea …
Substance P receptor blockade substantially ameliorated postoperative pain. Our findings underline the unique position of mast cells …
Multi-omics profiling predicts allograft function after lung transplantation.
Watzenboeck ML, Gorki AD, Quattrone F, Gawish R, Schwarz S, Lambers C, Jaksch P, Lakovits K, Zahalka S, Rahimi N, Starkl P, Symmank D, Artner T, Pattaroni C, Fortelny N, Klavins K, Frommlet F, Marsland BJ, Hoetzenecker K, Widder S, Knapp S. Watzenboeck ML, et al. Eur Respir J. 2022 Feb 3;59(2):2003292. doi: 10.1183/13993003.03292-2020. Print 2022 Feb. Eur Respir J. 2022. PMID: 34244315 Free article.
Epicutaneously applied Der p 2 induces a strong TH 2-biased antibody response in C57BL/6 mice, independent of functional TLR4.
Stremnitzer C, Manzano-Szalai K, Starkl P, Willensdorfer A, Schrom S, Singer J, Reichart U, Akira S, Jensen-Jarolim E. Stremnitzer C, et al. Allergy. 2014 Jun;69(6):741-51. doi: 10.1111/all.12399. Epub 2014 Apr 16. Allergy. 2014. PMID: 24735481 Free PMC article.
An asthma mouse model in TLR4-deficient mice recently suggested that the allergic immune response against Der p 2 is solely dependent on TLR4 signaling. We investigated whether similar mechanisms are important for Der p 2 sensitization via the skin. ...Barrier disru …
An asthma mouse model in TLR4-deficient mice recently suggested that the allergic immune response against Der p 2 is solely dependent …
IgE and mast cells in host defense against parasites and venoms.
Mukai K, Tsai M, Starkl P, Marichal T, Galli SJ. Mukai K, et al. Semin Immunopathol. 2016 Sep;38(5):581-603. doi: 10.1007/s00281-016-0565-1. Epub 2016 May 25. Semin Immunopathol. 2016. PMID: 27225312 Free PMC article. Review.
Establishing an allergic eczema model employing recombinant house dust mite allergens Der p 1 and Der p 2 in BALB/c mice.
Szalai K, Kopp T, Lukschal A, Stremnitzer C, Wallmann J, Starkl P, Vander Elst L, Saint-Remy JM, Pali-Schöll I, Jensen-Jarolim E. Szalai K, et al. Exp Dermatol. 2012 Nov;21(11):842-6. doi: 10.1111/exd.12015. Exp Dermatol. 2012. PMID: 23163649 Free PMC article.
The major house dust mite allergens Der p 1 and Der p 2 are prevalent inducers of eczema. Der p 1 is a cysteine protease disrupting epithelial barriers, whereas Der p 2 functionally mimics the LPS-binding compound MD-2 within the TLR4 complex. In this …
The major house dust mite allergens Der p 1 and Der p 2 are prevalent inducers of eczema. Der p 1 is a cysteine proteas …
Impact of glutathione on the allergenicity of the peach lipid transfer protein Pru p 3.
Gómez-Casado C, Tordesillas L, Kinkel J, Starkl P, Cuesta-Herranz J, Roth-Walter F, Díaz-Perales A, Jensen-Jarolim E. Gómez-Casado C, et al. J Investig Allergol Clin Immunol. 2015;25(1):47-54. J Investig Allergol Clin Immunol. 2015. PMID: 25898694 Free article.
RESULTS: GSH-reduced Pru p 3 produced variable skin prick reactions in peach-allergic patients. ...CONCLUSIONS: GSH can at least transiently reduce Pru p 3. We found that the effect of reduction on the allergenicity of Pru p 3 varied. ...
RESULTS: GSH-reduced Pru p 3 produced variable skin prick reactions in peach-allergic patients. ...CONCLUSIONS: GSH can at least tran …
Development of a novel, pan-variant aerosol intervention for COVID-19.
Shoemaker RH, Panettieri RA Jr, Libutti SK, Hochster HS, Watts NR, Wingfield PT, Starkl P, Pimenov L, Gawish R, Hladik A, Knapp S, Boring D, White JM, Lawrence Q, Boone J, Marshall JD, Matthews RL, Cholewa BD, Richig JW, Chen BT, McCormick DL, Gugensberger R, Höller S, Penninger JM, Wirnsberger G. Shoemaker RH, et al. bioRxiv [Preprint]. 2021 Sep 20:2021.09.14.459961. doi: 10.1101/2021.09.14.459961. bioRxiv. 2021. PMID: 34545364 Free PMC article. Updated. Preprint.
28 results