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Page 1
Triglyceride Lowering with Pemafibrate to Reduce Cardiovascular Risk.
Das Pradhan A, Glynn RJ, Fruchart JC, MacFadyen JG, Zaharris ES, Everett BM, Campbell SE, Oshima R, Amarenco P, Blom DJ, Brinton EA, Eckel RH, Elam MB, Felicio JS, Ginsberg HN, Goudev A, Ishibashi S, Joseph J, Kodama T, Koenig W, Leiter LA, Lorenzatti AJ, Mankovsky B, Marx N, Nordestgaard BG, Páll D, Ray KK, Santos RD, Soran H, Susekov A, Tendera M, Yokote K, Paynter NP, Buring JE, Libby P, Ridker PM; PROMINENT Investigators. Das Pradhan A, et al. N Engl J Med. 2022 Nov 24;387(21):1923-1934. doi: 10.1056/NEJMoa2210645. Epub 2022 Nov 5. N Engl J Med. 2022. PMID: 36342113 Clinical Trial.
2-Methoxy-4-methylsulfinylbenzyl Alcohol as a Safety-Catch Linker for the Fmoc/tBu Solid-Phase Peptide Synthesis Strategy.
Nandhini KP, Albericio F, de la Torre BG. Nandhini KP, et al. J Org Chem. 2022 Aug 5;87(15):9433-9442. doi: 10.1021/acs.joc.2c01057. Epub 2022 Jul 8. J Org Chem. 2022. PMID: 35801570
The peptide is detached in a two-step protocol, namely reduction of the sulfoxide to the sulfide with Me(3)SiCl and Ph(3)P, and then treatment with TFA. The advantage of this strategy has been demonstrated by the following: preparation of peptide with no diketopiperazine f …
The peptide is detached in a two-step protocol, namely reduction of the sulfoxide to the sulfide with Me(3)SiCl and Ph(3)P, and then …
Is there a role for upper gastrointestinal contrast study to predict the outcomes of sleeve gastrectomy? Lessons learnt from a prospective study.
Misra S, Balasubramanian S, Srikanth B, Kumar S, Christinajoice S, Nandhini D, Raj PP. Misra S, et al. J Minim Access Surg. 2022 Jan-Mar;18(1):97-104. doi: 10.4103/jmas.JMAS_186_20. J Minim Access Surg. 2022. PMID: 35017399 Free PMC article.
GEJ holdup time had no effect on percentage total weight loss (%TWL) (P = 0.09) or HbA1c improvement (P = 0.077). The absence of fundus led to greater %TWL at 6 months (P = 0.048). GDE time <15 s led to higher %TWL (P = 0.028) and lower HbA1c …
GEJ holdup time had no effect on percentage total weight loss (%TWL) (P = 0.09) or HbA1c improvement (P = 0.077). The absence …
2-Aminophenols based Schiff bases as fluorescent probes for selective detection of cyanide and aluminium ions - Effect of substituents.
Poongodi K, Saravana Kumar P, Shanmugapriya R, Nandhini C, Elango KP. Poongodi K, et al. Spectrochim Acta A Mol Biomol Spectrosc. 2021 Mar 15;249:119288. doi: 10.1016/j.saa.2020.119288. Epub 2020 Dec 3. Spectrochim Acta A Mol Biomol Spectrosc. 2021. PMID: 33326917
The mechanism of the probes' detection of CN involves deprotonation of the phenolic OH group(s) followed by nucleophilic addition of CN(-) onto imine C-atom. The (1)H NMR chemical shifts of the OH protons of 2-aminophenol moiety exhibits a linear correlation with the Hamme …
The mechanism of the probes' detection of CN involves deprotonation of the phenolic OH group(s) followed by nucleophilic addition of …
Mutational pressure dictates synonymous codon usage in freshwater unicellular α - cyanobacterial descendant Paulinella chromatophora and β - cyanobacterium Synechococcus elongatus PCC6301.
Nair RR, Nandhini MB, Sethuraman T, Doss G. Nair RR, et al. Springerplus. 2013 Sep 30;2:492. doi: 10.1186/2193-1801-2-492. eCollection 2013. Springerplus. 2013. PMID: 24255825 Free PMC article.
In the present study, we investigated various factors associated with synonymous codon usage in the genomes of P. chromatophora and S. elongatus PCC6301 and findings were discussed. ...However, correspondence analysis revealed that intensity of mutational pressure w …
In the present study, we investigated various factors associated with synonymous codon usage in the genomes of P. chromatophora and …
Sulforaphane potentially attenuates arsenic-induced nephrotoxicity via the PI3K/Akt/Nrf2 pathway in albino Wistar rats.
Thangapandiyan S, Ramesh M, Miltonprabu S, Hema T, Jothi GB, Nandhini V. Thangapandiyan S, et al. Environ Sci Pollut Res Int. 2019 Apr;26(12):12247-12263. doi: 10.1007/s11356-019-04502-w. Epub 2019 Mar 5. Environ Sci Pollut Res Int. 2019. PMID: 30835071 Free PMC article.

Notably, a significant (P < 0.05) increase was observed in markers of apoptosis, DNA damage, TUNEL-positive cells, and dark staining of ICAM-1 in renal tissue with decreased PI3K/Akt/Nrf2 gene expression. The biochemical findings were supported by histopathological and

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Notably, a significant (P < 0.05) increase was observed in markers of apoptosis, DNA damage, TUNEL-positive cells, and dark staini

…
Protective role of Cynodon dactylon in ameliorating the aluminium-induced neurotoxicity in rat brain regions.
Sumathi T, Shobana C, Kumari BR, Nandhini DN. Sumathi T, et al. Biol Trace Elem Res. 2011 Dec;144(1-3):843-53. doi: 10.1007/s12011-011-9029-6. Epub 2011 Mar 30. Biol Trace Elem Res. 2011. PMID: 21448563
Male albino rats were administered with AlCl(3) at a dose of 4.2 mg/kg/day i.p. for 4 weeks. Experimental rats were given C. dactylon extract in two different doses of 300 mg and 750 mg/keg/day orally 1 h prior to the AlCl(3) administration for 4 weeks. ...
Male albino rats were administered with AlCl(3) at a dose of 4.2 mg/kg/day i.p. for 4 weeks. Experimental rats were given C. dactylon …
Sulforaphane Potentially Ameliorates Arsenic Induced Hepatotoxicity in Albino Wistar Rats: Implication of PI3K/Akt/Nrf2 Signaling Pathway.
Thangapandiyan S, Ramesh M, Hema T, Miltonprabu S, Uddin MS, Nandhini V, Bavithra Jothi G. Thangapandiyan S, et al. Cell Physiol Biochem. 2019;52(5):1203-1222. doi: 10.33594/000000082. Cell Physiol Biochem. 2019. PMID: 31001960 Free article.
Furthermore, Arsenics treatments significantly (p<0.05) increased the pro-apoptotic marker (Bax) and DNA damage, with decreased Nrf2 protein responsible for liver protection. However, pretreatment with SFN significantly (p<0.05) decreased the levels of ALAD, A …
Furthermore, Arsenics treatments significantly (p<0.05) increased the pro-apoptotic marker (Bax) and DNA damage, with decreased Nr …
Bioavailability of metals in fly ash and their bioaccumulation in naturally occurring vegetation: a pilot scale study.
Maiti SK, Nandhini S. Maiti SK, et al. Environ Monit Assess. 2006 May;116(1-3):263-73. doi: 10.1007/s10661-006-7355-5. Environ Monit Assess. 2006. PMID: 16779594
FA samples had a neutral pH, low electrical conductivity, low organic C and trace amounts of N and P. The relative abundance of total metals in FA were found in the order Fe >Mn >Zn >Ni >Co>Cu. ...
FA samples had a neutral pH, low electrical conductivity, low organic C and trace amounts of N and P. The relative abundance of total …