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Rivaroxaban in Rheumatic Heart Disease-Associated Atrial Fibrillation.
Connolly SJ, Karthikeyan G, Ntsekhe M, Haileamlak A, El Sayed A, El Ghamrawy A, Damasceno A, Avezum A, Dans AML, Gitura B, Hu D, Kamanzi ER, Maklady F, Fana G, Gonzalez-Hermosillo JA, Musuku J, Kazmi K, Zühlke L, Gondwe L, Ma C, Paniagua M, Ogah OS, Molefe-Baikai OJ, Lwabi P, Chillo P, Sharma SK, Cabral TTJ, Tarhuni WM, Benz A, van Eikels M, Krol A, Pattath D, Balasubramanian K, Rangarajan S, Ramasundarahettige C, Mayosi B, Yusuf S; INVICTUS Investigators. Connolly SJ, et al. N Engl J Med. 2022 Sep 15;387(11):978-988. doi: 10.1056/NEJMoa2209051. Epub 2022 Aug 28. N Engl J Med. 2022. PMID: 36036525 Clinical Trial.
Permanent discontinuation of trial medication was more common with rivaroxaban than with vitamin K antagonist therapy at all visits. In the intention-to-treat analysis, 560 patients in the rivaroxaban group and 446 in the vitamin K antagonist group had a primary-out …
Permanent discontinuation of trial medication was more common with rivaroxaban than with vitamin K antagonist therapy at all visits. …
Apixaban to Prevent Venous Thromboembolism in Patients with Cancer.
Carrier M, Abou-Nassar K, Mallick R, Tagalakis V, Shivakumar S, Schattner A, Kuruvilla P, Hill D, Spadafora S, Marquis K, Trinkaus M, Tomiak A, Lee AYY, Gross PL, Lazo-Langner A, El-Maraghi R, Goss G, Le Gal G, Stewart D, Ramsay T, Rodger M, Witham D, Wells PS; AVERT Investigators. Carrier M, et al. N Engl J Med. 2019 Feb 21;380(8):711-719. doi: 10.1056/NEJMoa1814468. Epub 2018 Dec 4. N Engl J Med. 2019. PMID: 30511879 Clinical Trial.
Venous thromboembolism occurred in 12 of 288 patients (4.2%) in the apixaban group and in 28 of 275 patients (10.2%) in the placebo group (hazard ratio, 0.41; 95% confidence interval [CI], 0.26 to 0.65; P<0.001). In the modified intention-to-treat analysis, major bleedi …
Venous thromboembolism occurred in 12 of 288 patients (4.2%) in the apixaban group and in 28 of 275 patients (10.2%) in the placebo group (h …
Free-Base Corrole Anion.
Tarai A, Mallick J, Singh P, Conradie J, Kar S, Ghosh A. Tarai A, et al. J Org Chem. 2023 Sep 15;88(18):13022-13029. doi: 10.1021/acs.joc.3c01125. Epub 2023 Aug 30. J Org Chem. 2023. PMID: 37647416 Free PMC article.
Presented here is a first crystal structure of a free-base corrole anion, derived from tris(p-cyanophenyl)corrole, as the tetrabuylammonium salt. The low-temperature (100 K) structure reveals localized hydrogens on a pair of opposite pyrrole nitrogens. ...
Presented here is a first crystal structure of a free-base corrole anion, derived from tris(p-cyanophenyl)corrole, as the tetrabuylam …
Risk for Recurrent Venous Thromboembolism in Patients With Subsegmental Pulmonary Embolism Managed Without Anticoagulation : A Multicenter Prospective Cohort Study.
Le Gal G, Kovacs MJ, Bertoletti L, Couturaud F, Dennie C, Hirsch AM, Huisman MV, Klok FA, Kraaijpoel N, Mallick R, Pecarskie A, Pena E, Phillips P, Pichon I, Ramsay T, Righini M, Rodger MA, Roy PM, Sanchez O, Schmidt J, Schulman S, Shivakumar S, Trinh-Duc A, Verdet R, Vinsonneau U, Wells P, Wu C, Yeo E, Carrier M; SSPE Investigators. Le Gal G, et al. Ann Intern Med. 2022 Jan;175(1):29-35. doi: 10.7326/M21-2981. Epub 2021 Nov 23. Ann Intern Med. 2022. PMID: 34807722
Antithrombotic Treatment for Stroke Prevention in Cervical Artery Dissection: The STOP-CAD Study.
Yaghi S, Shu L, Mandel D, Leon Guerrero CR, Henninger N, Muppa J, Affan M, Ul Haq Lodhi O, Heldner MR, Antonenko K, Seiffge D, Arnold M, Salehi Omran S, Crandall R, Lester E, Lopez Mena D, Arauz A, Nehme A, Boulanger M, Touze E, Sousa JA, Sargento-Freitas J, Barata V, Castro-Chaves P, Brito MT, Khan M, Mallick D, Rothstein A, Khazaal O, Kaufmann JE, Engelter ST, Traenka C, Aguiar de Sousa D, Soares M, Rosa S, Zhou LW, Gandhi P, Field TS, Mancini S, Metanis I, Leker RR, Pan K, Dantu V, Baumgartner K, Burton T, Von Rennenberg R, Nolte CH, Choi R, MacDonald J, Bavarsad Shahripour R, Guo X, Ghannam M, Almajali M, Samaniego EA, Sanchez S, Rioux B, Zine-Eddine F, Poppe A, Fonseca AC, Baptista MF, Cruz D, Romoli M, De Marco G, Longoni M, Keser Z, Griffin K, Kuohn L, Frontera J, Amar J, Giles J, Zedde M, Pascarella R, Grisendi I, Nzwalo H, Liebeskind DS, Molaie A, Cavalier A, Kam W, Mac Grory B, Al Kasab S, Anadani M, Kicielinski K, Eltatawy A, Chervak L, Chulluncuy-Rivas R, Aziz Y, Bakradze E, Tran TL, Rodrigo-Gisbert M, Requena M, Saleh Velez F, Ortiz Gracia J, Mudassani V, de Havenon A, Vishnu VY, Yaddanapudi S, Adams L, Browngoehl A, Ranasinghe T, Dunston R, Lynch Z, Penckofer M, Sieg… See abstract for full author list ➔ Yaghi S, et al. Stroke. 2024 Apr;55(4):908-918. doi: 10.1161/STROKEAHA.123.045731. Epub 2024 Feb 9. Stroke. 2024. PMID: 38335240 Free article.
In adjusted Cox regression with inverse probability of treatment weighting, compared with antiplatelet therapy, anticoagulation was associated with a nonsignificantly lower risk of subsequent ischemic stroke by day 30 (adjusted hazard ratio [HR], 0.71 [95% CI, 0.45-1.12]; P …
In adjusted Cox regression with inverse probability of treatment weighting, compared with antiplatelet therapy, anticoagulation was associat …
COVID-19 Infection in Pregnancy: A Review.
Mily SJ, Akter KM, Jabin N, Mitra S, Emran TB, Nandi M, Baral SK, Uddin MZ, Mallick J, Paul A, Shah SUA, Rauf A, Khan IN, Mubarak MS. Mily SJ, et al. Infect Disord Drug Targets. 2022;22(5):e050122199976. doi: 10.2174/1871526522666220105111358. Infect Disord Drug Targets. 2022. PMID: 34986776 Review.
Polypill with or without Aspirin in Persons without Cardiovascular Disease.
Yusuf S, Joseph P, Dans A, Gao P, Teo K, Xavier D, López-Jaramillo P, Yusoff K, Santoso A, Gamra H, Talukder S, Christou C, Girish P, Yeates K, Xavier F, Dagenais G, Rocha C, McCready T, Tyrwhitt J, Bosch J, Pais P; International Polycap Study 3 Investigators. Yusuf S, et al. N Engl J Med. 2021 Jan 21;384(3):216-228. doi: 10.1056/NEJMoa2028220. Epub 2020 Nov 13. N Engl J Med. 2021. PMID: 33186492 Free PMC article. Clinical Trial.
Inverting the Electronic Structure of Diylidylgermylenes by Backbone Modification.
Swamy VSVSN, Krischer F, Schwarz C, Steinert H, Mallick B, Gessner VH. Swamy VSVSN, et al. Chemistry. 2023 Jun 2;29(31):e202300504. doi: 10.1002/chem.202300504. Epub 2023 Apr 20. Chemistry. 2023. PMID: 36929100
Attempts to synthesize the germylene (Y(CN) )(2) Ge [with Y(CN) =Ph(3) P-(C)-CN] from the corresponding metalated ylide Y(CN) K selectively led to germanide [(Y(CN) )(3) Ge)K](2) thus reflecting the electrophilic nature of the intermediate formed germylene. X …
Attempts to synthesize the germylene (Y(CN) )(2) Ge [with Y(CN) =Ph(3) P-(C)-CN] from the corresponding metalated ylide Y(CN) K …
Quantitative Evaluation of Apically Extruded Debris during Biomechanical Preparation using Hand K-File, Protaper Next, and Waveone - An In Vitro Study.
Maheswari D, Mallick RR, Shandilya A, Solanki H, Panda S, Sarangi P. Maheswari D, et al. J Pharm Bioallied Sci. 2022 Jul;14(Suppl 1):S802-S807. doi: 10.4103/jpbs.jpbs_194_22. Epub 2022 Jul 13. J Pharm Bioallied Sci. 2022. PMID: 36110614 Free PMC article.

Weight of dry debris was measured using electronic microbalance with an accuracy of 10(-5) g. STATISTICAL ANALYSIS: Student's t-test, with P value < 0.05 is statistically significant. RESULTS: Statistically significant (P < 0.05) amount of debris was extruded

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Weight of dry debris was measured using electronic microbalance with an accuracy of 10(-5) g. STATISTICAL ANALYSIS: Student's t-test, with …
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