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Page 1
Efficacy and Safety of Low-Dose Colchicine after Myocardial Infarction.
Tardif JC, Kouz S, Waters DD, Bertrand OF, Diaz R, Maggioni AP, Pinto FJ, Ibrahim R, Gamra H, Kiwan GS, Berry C, López-Sendón J, Ostadal P, Koenig W, Angoulvant D, Grégoire JC, Lavoie MA, Dubé MP, Rhainds D, Provencher M, Blondeau L, Orfanos A, L'Allier PL, Guertin MC, Roubille F. Tardif JC, et al. N Engl J Med. 2019 Dec 26;381(26):2497-2505. doi: 10.1056/NEJMoa1912388. Epub 2019 Nov 16. N Engl J Med. 2019. PMID: 31733140 Free article. Clinical Trial.
The primary end point occurred in 5.5% of the patients in the colchicine group, as compared with 7.1% of those in the placebo group (hazard ratio, 0.77; 95% confidence interval [CI], 0.61 to 0.96; P = 0.02). The hazard ratios were 0.84 (95% CI, 0.46 to 1.52) for death from …
The primary end point occurred in 5.5% of the patients in the colchicine group, as compared with 7.1% of those in the placebo group (hazard …
Evaluation of mRNA-1273 Vaccine in Children 6 Months to 5 Years of Age.
Anderson EJ, Creech CB, Berthaud V, Piramzadian A, Johnson KA, Zervos M, Garner F, Griffin C, Palanpurwala K, Turner M, Gerber J, Bennett RL, Ali K, Ampajwala M, Berman G, Nayak J, Chronis C, Rizzardi B, Muller WJ, Smith CA, Fuchs G, Hsia D, Tomassini JE, DeLucia D, Reuter C, Kuter B, Zhao X, Deng W, Zhou H, Ramirez Schrempp D, Hautzinger K, Girard B, Slobod K, McPhee R, Pajon R, Aunins A, Das R, Miller JM, Schnyder Ghamloush S; KidCOVE Study Group. Anderson EJ, et al. N Engl J Med. 2022 Nov 3;387(18):1673-1687. doi: 10.1056/NEJMoa2209367. Epub 2022 Oct 19. N Engl J Med. 2022. PMID: 36260859 Free PMC article. Clinical Trial.
Evaluation of mRNA-1273 Covid-19 Vaccine in Children 6 to 11 Years of Age.
Creech CB, Anderson E, Berthaud V, Yildirim I, Atz AM, Melendez Baez I, Finkelstein D, Pickrell P, Kirstein J, Yut C, Blair R, Clifford RA, Dunn M, Campbell JD, Montefiori DC, Tomassini JE, Zhao X, Deng W, Zhou H, Ramirez Schrempp D, Hautzinger K, Girard B, Slobod K, McPhee R, Pajon R, Das R, Miller JM, Schnyder Ghamloush S; KidCOVE Study Group. Creech CB, et al. N Engl J Med. 2022 May 26;386(21):2011-2023. doi: 10.1056/NEJMoa2203315. Epub 2022 May 11. N Engl J Med. 2022. PMID: 35544369 Free PMC article. Clinical Trial.
Serum Coenzyme Q10 Levels are Decreased in Critically-Ill Septic Patients: Results From a Preliminary Study.
Vassiliou AG, Mastora Z, Jahaj E, Keskinidou C, Pratikaki ME, Kampisiouli E, Orfanos SE, Kotanidou A, Dimopoulou I. Vassiliou AG, et al. Biol Res Nurs. 2021 Apr;23(2):198-207. doi: 10.1177/1099800420944489. Epub 2020 Jul 24. Biol Res Nurs. 2021. PMID: 32705879

RESULTS: On admission, ICU patients who developed sepsis had lower CoQ10 levels compared to healthy controls (0.89 vs. 1.04 g/ml, p < 0.05), while at sepsis and septic shock CoQ10 levels decreased further (0.63 g/ml; p < 0.001 and 0.42 g/m

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RESULTS: On admission, ICU patients who developed sepsis had lower CoQ10 levels compared to healthy controls (0.89 vs. 1.04 g/ml, …
Removal of caffeine, nicotine and amoxicillin from (waste)waters by various adsorbents. A review.
Anastopoulos I, Pashalidis I, Orfanos AG, Manariotis ID, Tatarchuk T, Sellaoui L, Bonilla-Petriciolet A, Mittal A, Núñez-Delgado A. Anastopoulos I, et al. J Environ Manage. 2020 May 1;261:110236. doi: 10.1016/j.jenvman.2020.110236. Epub 2020 Mar 2. J Environ Manage. 2020. PMID: 32148306 Review.
The review covers the toxic effect caused by caffeine, nicotine and amoxicillin on humans and animals and describes some of the main adsorbents utilized for their removal (e.g., grape stalk, tea waste, wheat grains, bentonite, activated carbon, acid and base modified grape …
The review covers the toxic effect caused by caffeine, nicotine and amoxicillin on humans and animals and describes some of the main adsorbe …
Global, regional and national consumption of major food groups in 1990 and 2010: a systematic analysis including 266 country-specific nutrition surveys worldwide.
Micha R, Khatibzadeh S, Shi P, Andrews KG, Engell RE, Mozaffarian D; Global Burden of Diseases Nutrition and Chronic Diseases Expert Group (NutriCoDE). Micha R, et al. BMJ Open. 2015 Sep 24;5(9):e008705. doi: 10.1136/bmjopen-2015-008705. BMJ Open. 2015. PMID: 26408285 Free PMC article.
Country-specific vegetable intake ranged from 34.6-493.1 g/day (global mean=208.8 g/day); corresponding values for nuts/seeds were 0.2-152.7 g/day (8.9 g/day); for whole grains, 1.3-334.3 g/day (38.4 g/day); for seafood, 6.0-87.6 g …
Country-specific vegetable intake ranged from 34.6-493.1 g/day (global mean=208.8 g/day); corresponding values for nuts/seeds …
Effect of Triiodothyronine Administration on the Kidney During Haemorrhagic Shock and Resuscitation.
Karmaniolou I, Lamprou K, Staikou C, Giamarellos-Bourboulis E, Theodoraki K, Papalois A, Mylonas A, Orfanos N, Smyrniotis V, Arkadopoulos N. Karmaniolou I, et al. Turk J Anaesthesiol Reanim. 2020 Oct;48(5):406-413. doi: 10.5152/TJAR.2019.81542. Epub 2020 Feb 5. Turk J Anaesthesiol Reanim. 2020. PMID: 33103146 Free PMC article.
Group-T3 required less normal saline (Group-T3: 1083204 mL versus F: 2500547 mL, p=0.001) and hydroxyethyl starch (Group-T3: 558102 mL versus F: 916204 mL, p=0.004) during resuscitation. ...Apoptosis, assessed by renal caspase-3 activity, was increased in Group-T3 ( …
Group-T3 required less normal saline (Group-T3: 1083204 mL versus F: 2500547 mL, p=0.001) and hydroxyethyl starch (Group-T3: 558102 m …
FLNC-Associated Myofibrillar Myopathy: New Clinical, Functional, and Proteomic Data.
Kley RA, Leber Y, Schrank B, Zhuge H, Orfanos Z, Kostan J, Onipe A, Sellung D, Güttsches AK, Eggers B, Jacobsen F, Kress W, Marcus K, Djinovic-Carugo K, van der Ven PFM, Fürst DO, Vorgerd M. Kley RA, et al. Neurol Genet. 2021 May 18;7(3):e590. doi: 10.1212/NXG.0000000000000590. eCollection 2021 Jun. Neurol Genet. 2021. PMID: 34235269 Free PMC article.
RESULTS: Eight patients revealed clinical features of slowly progressive proximal weakness associated with a heterozygous c.8025_8030delCAAGACinsA (p.K2676Pfs*3) mutation in FLNC. Two patients exhibited a mild cardiomyopathy. ...
RESULTS: Eight patients revealed clinical features of slowly progressive proximal weakness associated with a heterozygous c.8025_8030delCAAG …
Low Admission Immunoglobulin G Levels Predict Poor Outcome in Patients with Mild-to-Critical COVID-19: A Prospective, Single-Center Study.
Vrettou CS, Vassiliou AG, Kakkas I, Jahaj E, Tsipilis S, Athanasiou N, Zacharis A, Keskinidou C, Papageorgiou A, Orfanos SE, Kotanidou A, Dimopoulou I. Vrettou CS, et al. J Epidemiol Glob Health. 2021 Dec;11(4):338-343. doi: 10.1007/s44197-021-00002-8. Epub 2021 Aug 10. J Epidemiol Glob Health. 2021. PMID: 34734379 Free PMC article.

Median IgG levels of survivors were significantly higher than non-survivors (p < 0.01). The cohort was subsequently divided in IgG deficient (< 690 mg/dl) and sufficient ( 690 mg/dl) patients. IgG-deficient patients had a higher mortality rate (p < 0.01). T

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Median IgG levels of survivors were significantly higher than non-survivors (p < 0.01). The cohort was subsequently divided in IgG

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Evaluating risk factors following surgery for periprosthetic fractures around hip and knee arthroplasties.
Orfanos G, Lim J, Youssef B. Orfanos G, et al. Arch Orthop Trauma Surg. 2019 Apr;139(4):475-482. doi: 10.1007/s00402-018-3084-9. Epub 2018 Dec 7. Arch Orthop Trauma Surg. 2019. PMID: 30535719
Survival analysis showed a correlation between age more than 75 years old (p = 0.001), ASA grade of 3 or higher (p = 0.009 Breslow's test), history of CVA or TIA (p = 0.038 Breslow's test), dementia (p = 0.002 log rank test), depression (p = 0.0 …
Survival analysis showed a correlation between age more than 75 years old (p = 0.001), ASA grade of 3 or higher (p = 0.009 Bre …
32 results