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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1967 1
1975 5
1976 8
1977 6
1978 6
1979 4
1980 9
1981 9
1982 9
1983 12
1984 21
1985 25
1986 13
1987 43
1988 61
1989 72
1990 86
1991 97
1992 112
1993 119
1994 118
1995 123
1996 154
1997 154
1998 204
1999 232
2000 245
2001 243
2002 255
2003 284
2004 314
2005 321
2006 320
2007 282
2008 335
2009 344
2010 422
2011 419
2012 421
2013 491
2014 609
2015 782
2016 928
2017 1046
2018 1088
2019 1101
2020 1337
2021 1470
2022 1369
2023 1277
2024 588

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15,599 results

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Page 1
Prevalence of lumbar spondylolysis and spondylolisthesis in patients with degenerative spinal disease.
Aoki Y, Takahashi H, Nakajima A, Kubota G, Watanabe A, Nakajima T, Eguchi Y, Orita S, Fukuchi H, Yanagawa N, Nakagawa K, Ohtori S. Aoki Y, et al. Sci Rep. 2020 Apr 21;10(1):6739. doi: 10.1038/s41598-020-63784-0. Sci Rep. 2020. PMID: 32317683 Free PMC article.

Of these 37 patients, 19 patients (51.4%) showed spondylolisthesis, whereas only 7.4% of non-spondylolysis patients showed spondylolisthesis (p < 0.05). When excluding unilateral spondylolysis, 90% (18/20) of spondylolysis patients aged 60 years-old showed spondylolisth

…
Of these 37 patients, 19 patients (51.4%) showed spondylolisthesis, whereas only 7.4% of non-spondylolysis patients showed spondylolisthesis …
Efficacy and safety of mirogabalin for chemotherapy-induced peripheral neuropathy: a prospective single-arm trial (MiroCIP study).
Misawa S, Denda T, Kodama S, Suzuki T, Naito Y, Kogawa T, Takada M, Suichi T, Shiosakai K, Kuwabara S; MiroCIP study group. Misawa S, et al. BMC Cancer. 2023 Nov 11;23(1):1098. doi: 10.1186/s12885-023-11560-4. BMC Cancer. 2023. PMID: 37951905 Free PMC article. Clinical Trial.

From baseline to week 12 (last observation carried forward [LOCF]), NRS score decreased by 30.9%: mean change (95% confidence interval [CI]), - 1.7 (- 2.4 to - 1.0) (p < 0.001). Patients with baseline NRS of 6 experienced a 44.0% reduction in score from baseline to week

…
From baseline to week 12 (last observation carried forward [LOCF]), NRS score decreased by 30.9%: mean change (95% confidence interval [CI]) …
Catalytic asymmetric synthesis of alpha-methyl-p-boronophenylalanine.
Harada S, Kajihara R, Muramoto R, Jutabha P, Anzai N, Nemoto T. Harada S, et al. Bioorg Med Chem Lett. 2018 Jun 1;28(10):1915-1918. doi: 10.1016/j.bmcl.2018.03.075. Epub 2018 Mar 28. Bioorg Med Chem Lett. 2018. PMID: 29655983
p-Boronophenylalanine (l-BPA) is applied in clinical settings as a boron carrier for boron neutron capture therapy (BNCT) to cure malignant melanomas. ...
p-Boronophenylalanine (l-BPA) is applied in clinical settings as a boron carrier for boron neutron capture therapy (BNCT) to cure mal …
Erratum: figure correction.
Li SX, Zhang JC, Wu J, Hashimoto K. Li SX, et al. Clin Psychopharmacol Neurosci. 2014 Dec;12(3):243. doi: 10.9758/cpn.2014.12.3.243. Clin Psychopharmacol Neurosci. 2014. PMID: 25599759 Free PMC article.
[This corrects the article on p. 124 in vol. 12, PMID: 25191502.]....
[This corrects the article on p. 124 in vol. 12, PMID: 25191502.]....
Delivery of aPD-L1 antibody to i.p. tumors via direct penetration by i.p. route: Beyond EPR effect.
Yamamoto M, Kurino T, Matsuda R, Jones HS, Nakamura Y, Kanamori T, Tsuji AB, Sugyo A, Tsuda R, Matsumoto Y, Sakurai Y, Suzuki H, Sano M, Osada K, Uehara T, Ishii Y, Akita H, Arano Y, Hisaka A, Hatakeyama H. Yamamoto M, et al. J Control Release. 2022 Dec;352:328-337. doi: 10.1016/j.jconrel.2022.10.032. Epub 2022 Oct 26. J Control Release. 2022. PMID: 36280153
After i.p. administration, the amount of anti-PD-L1 antibody transferred into i.p. tumors increased by approximately eight folds compared to that after i.v. administration. ...Owing to the enhanced delivery, the therapeutic efficacy of anti-PD-L1 antibody in the per …
After i.p. administration, the amount of anti-PD-L1 antibody transferred into i.p. tumors increased by approximately eight fol …
Cryo-EM structure of P-glycoprotein bound to triple elacridar inhibitor molecules.
Hamaguchi-Suzuki N, Adachi N, Moriya T, Yasuda S, Kawasaki M, Suzuki K, Ogasawara S, Anzai N, Senda T, Murata T. Hamaguchi-Suzuki N, et al. Biochem Biophys Res Commun. 2024 May 21;709:149855. doi: 10.1016/j.bbrc.2024.149855. Epub 2024 Mar 28. Biochem Biophys Res Commun. 2024. PMID: 38579618 Free article.
P-glycoprotein (P-gp) is an ATP-binding cassette transporter known for its roles in expelling xenobiotic compounds from cells and contributing to cellular drug resistance through multidrug efflux. This mechanism is particularly problematic in cancer cells, where it …
P-glycoprotein (P-gp) is an ATP-binding cassette transporter known for its roles in expelling xenobiotic compounds from cells …
Identification of genotype-biochemical phenotype correlations associated with fructose 1,6-bisphosphatase deficiency.
Sakuma I, Nagano H, Hashimoto N, Fujimoto M, Nakayama A, Fuchigami T, Taki Y, Matsuda T, Akamine H, Kono S, Kono T, Yokoyama M, Nishimura M, Yokote K, Ogasawara T, Fujii Y, Ogawa S, Lee E, Miki T, Tanaka T. Sakuma I, et al. Commun Biol. 2023 Jul 28;6(1):787. doi: 10.1038/s42003-023-05160-y. Commun Biol. 2023. PMID: 37507476 Free PMC article.
Here we identify compound heterozygous missense mutations of FBP1, c.491G>A (p.G164D) and c.581T>C (p.F194S), in an adult patient with hypoglycemic lactic acidosis. ...
Here we identify compound heterozygous missense mutations of FBP1, c.491G>A (p.G164D) and c.581T>C (p.F194S), in an adul …
Cinnamoyl amide type chiral P,olefin ligands for Pd-catalyzed reactions.
Mino T, Fujisawa Y, Yoshida S, Hirama M, Akiyama T, Saito R, Yoshida Y, Kasashima Y, Sakamoto M. Mino T, et al. Org Biomol Chem. 2021 Dec 8;19(47):10385-10389. doi: 10.1039/d1ob02086b. Org Biomol Chem. 2021. PMID: 34821903
We synthesized cinnamoyl amide type chiral P,olefin ligand (S)-4. We successfully obtained separable diastereomers of 4d and demonstrated Pd-catalyzed asymmetric allylic substitution reactions of indoles using (S,aS)-4d as a chiral ligand with high enantioselectivities (up …
We synthesized cinnamoyl amide type chiral P,olefin ligand (S)-4. We successfully obtained separable diastereomers of 4d and demonstr …
Impact of Early Treatment with Intravenous High-Dose Methylprednisolone for Ocular Myasthenia Gravis.
Uzawa A, Suzuki S, Kuwabara S, Akamine H, Onishi Y, Yasuda M, Ozawa Y, Kawaguchi N, Kubota T, Takahashi MP, Suzuki Y, Watanabe G, Kimura T, Sugimoto T, Samukawa M, Minami N, Masuda M, Konno S, Nagane Y, Utsugisawa K. Uzawa A, et al. Neurotherapeutics. 2023 Mar;20(2):518-523. doi: 10.1007/s13311-022-01335-3. Epub 2023 Jan 6. Neurotherapeutics. 2023. PMID: 36607596 Free PMC article.
Despite having greater clinical severity before immunotherapy and lower oral prednisolone doses throughout the course, the early IVMP group (n = 55) showed a higher rate of achievement of MM (P = 0.0040, log-rank test; hazard ratio 1.58, 95% confidence interval [CI] 1.13-2 …
Despite having greater clinical severity before immunotherapy and lower oral prednisolone doses throughout the course, the early IVMP group …
15,599 results
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