Functionalization of 6-nitrobenzo[1,3]dioxole with carbonyl compounds via TDAE methodology

Ouassila Amiri-Attou; Thierry Terme; Patrice Vanelle

doi:10.3390/10030545

Functionalization of 6-nitrobenzo[1,3]dioxole with carbonyl compounds via TDAE methodology

Molecules. 2005 May 13;10(3):545-51. doi: 10.3390/10030545.

Authors

Ouassila Amiri-Attou¹, Thierry Terme, Patrice Vanelle

Affiliation

¹ Laboratoire de Chimie Organique Pharmaceutique, CNRS-UMR 6517, Faculté de Pharmacie, 27 Bd Jean Moulin, 13385 Marseille Cx 5, France.

Abstract

We report herein the synthesis of substituted 2-(6-nitrobenzo[1,3]dioxol-5-yl)-1- aryl ethanols and 2-(6-nitrobenzo[1,3]dioxol-5-yl)-propionic acid ethyl esters from the reaction of 5-chloromethyl-6-nitrobenzo[1,3]dioxole with various aromatic carbonyl and alpha- carbonyl ester derivatives using the tetrakis(dimethylamino)ethylene (TDAE) methodology.

MeSH terms

Benzodioxoles / chemistry*
Deanol / chemistry*
Indicators and Reagents
Magnetic Resonance Spectroscopy
Models, Molecular
Nitrobenzoates / chemistry*

Substances

Benzodioxoles
Indicators and Reagents
Nitrobenzoates
Deanol