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oskar linings
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Oskars Linins
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Evaluation of optimized bronchoalveolar lavage sampling designs for characterization of pulmonary drug distribution.
J Pharmacokinet Pharmacodyn. 2015 Dec;42(6):699-708. doi: 10.1007/s10928-015-9438-9. Epub 2015 Aug 28.
J Pharmacokinet Pharmacodyn. 2015.
PMID: 26316105
Free PMC article.
Bronchoalveolar lavage (BAL) is a pulmonary sampling technique for characterization of drug concentrations in epithelial lining fluid and alveolar cells. Two hypothetical drugs with different pulmonary distribution rates (fast and slow) were considered. ...
Bronchoalveolar lavage (BAL) is a pulmonary sampling technique for characterization of drug concentrations in epithelial lining fluid …
Signatures of a jet cocoon in early spectra of a supernova associated with a γ-ray burst.
Izzo L, de Ugarte Postigo A, Maeda K, Thöne CC, Kann DA, Della Valle M, Sagues Carracedo A, Michałowski MJ, Schady P, Schmidl S, Selsing J, Starling RLC, Suzuki A, Bensch K, Bolmer J, Campana S, Cano Z, Covino S, Fynbo JPU, Hartmann DH, Heintz KE, Hjorth J, Japelj J, Kamiński K, Kaper L, Kouveliotou C, Krużyński M, Kwiatkowski T, Leloudas G, Levan AJ, Malesani DB, Michałowski T, Piranomonte S, Pugliese G, Rossi A, Sánchez-Ramírez R, Schulze S, Steeghs D, Tanvir NR, Ulaczyk K, Vergani SD, Wiersema K.
Izzo L, et al.
Nature. 2019 Jan;565(7739):324-327. doi: 10.1038/s41586-018-0826-3. Epub 2019 Jan 16.
Nature. 2019.
PMID: 30651614
Long gamma-ray bursts are associated with energetic, broad-lined, stripped-envelope supernovae(1,2) and as such mark the death of massive stars. ...
Long gamma-ray bursts are associated with energetic, broad-lined, stripped-envelope supernovae(1,2) and as such mark the death of mas …
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A pharmacometric pulmonary model predicting the extent and rate of distribution from plasma to epithelial lining fluid and alveolar cells--using rifampicin as an example.
Clewe O, Goutelle S, Conte JE Jr, Simonsson US.
Clewe O, et al.
Eur J Clin Pharmacol. 2015 Mar;71(3):313-9. doi: 10.1007/s00228-014-1798-3. Epub 2015 Jan 27.
Eur J Clin Pharmacol. 2015.
PMID: 25620089
Free PMC article.
Clinical Trial.
PURPOSE: The purpose of the study was to develop a drug-unspecific approach to pharmacometric modeling for predicting the rate and extent of distribution from plasma to epithelial lining fluid (ELF) and alveolar cells (AC) for data emanating from studies involving bronchoa …
PURPOSE: The purpose of the study was to develop a drug-unspecific approach to pharmacometric modeling for predicting the rate and extent of …
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