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Combining experiment and energy landscapes to explore anaerobic heme breakdown in multifunctional hemoproteins.
Phys Chem Chem Phys. 2024 Jan 3;26(2):695-712. doi: 10.1039/d3cp03897a.
Phys Chem Chem Phys. 2024.
PMID: 38053511
Review.
Ultrahigh-Throughput Directed Evolution of a Metal-Free α/β-Hydrolase with a Cys-His-Asp Triad into an Efficient Phosphotriesterase.
Schnettler JD, Klein OJ, Kaminski TS, Colin PY, Hollfelder F.
Schnettler JD, et al. Among authors: klein oj.
J Am Chem Soc. 2023 Jan 18;145(2):1083-1096. doi: 10.1021/jacs.2c10673. Epub 2022 Dec 30.
J Am Chem Soc. 2023.
PMID: 36583539
Free PMC article.
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Controlled Ligand Exchange Between Ruthenium Organometallic Cofactor Precursors and a Naïve Protein Scaffold Generates Artificial Metalloenzymes Catalysing Transfer Hydrogenation.
Biggs GS, Klein OJ, Maslen SL, Skehel JM, Rutherford TJ, Freund SMV, Hollfelder F, Boss SR, Barker PD.
Biggs GS, et al. Among authors: klein oj.
Angew Chem Int Ed Engl. 2021 May 3;60(19):10919-10927. doi: 10.1002/anie.202015834. Epub 2021 Mar 26.
Angew Chem Int Ed Engl. 2021.
PMID: 33616271
Free PMC article.
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