Problems and solutions in IGRT for cervical cancer

Rep Pract Oncol Radiother. 2018 Nov-Dec;23(6):517-527. doi: 10.1016/j.rpor.2018.05.002. Epub 2018 May 26.

Abstract

The contribution of Image-guided Radiotherapy (IGRT) to modern radiotherapy is undeniable, being the way to bring into daily practice the dosimetric benefits of Intensity-Modulated Radiotherapy (IMRT). Organ and target motion is constant and unpredictable at the pelvis, thus posing a challenge to the safe execution of IMRT. There are potential benefits of IMRT in the radical treatment of cervical cancer patients, both in terms of dose escalation and decrease of toxicity. But it is essential to find IGRT solutions to control the aspects that can lead to geographic miss targeting or organs at risk (OAR) overdose. This review seeks to describe the problems and possible solutions in the clinical implementation of IMRT/IGRT protocols to treat intact cervical cancer patients.

Keywords: CBCT in cervical cancer; Cervical cancer treatment; Image guidance; Organ motion; Pelvic IGRT; Pelvic IMRT.

Publication types

  • Review