[Electron microscopic study of nuclear inclusions induced by Vinca alkaloid derivatives]

S Zoltán; C Orsolya; S János

[Electron microscopic study of nuclear inclusions induced by Vinca alkaloid derivatives]

Morphol Igazsagugyi Orv Sz. 1976 Oct;16(4):265-9.

[Article in Hungarian]

Authors

S Zoltán, C Orsolya, S János

PMID: 1012287

Abstract

Authors in the nuclei of Ehrlich-ascites tumour cells as an effect of the derivates of Vinca alkaloids observed formation of inclusions of fibrous, globular and crystalloid type. These structures were examined electronmicroscopically. Author assume, that the formation of these inclusions is a result of the precipitation of the nucleoprotein by the alkaloid.

Publication types

English Abstract

MeSH terms

Animals
Carcinoma, Ehrlich Tumor / ultrastructure*
Cytoplasmic Granules / drug effects
Cytoplasmic Granules / ultrastructure*
In Vitro Techniques
Vinblastine / pharmacology*

Substances

Vinblastine