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Showing results for orlando alone
Search for Orlando Palone instead (1 results)
Rationale and trial design of NATALEE: a Phase III trial of adjuvant ribociclib + endocrine therapy versus endocrine therapy alone in patients with HR+/HER2- early breast cancer.
Slamon DJ, Fasching PA, Hurvitz S, Chia S, Crown J, Martín M, Barrios CH, Bardia A, Im SA, Yardley DA, Untch M, Huang CS, Stroyakovskiy D, Xu B, Moroose RL, Loi S, Visco F, Bee-Munteanu V, Afenjar K, Fresco R, Taran T, Chakravartty A, Zarate JP, Lteif A, Hortobagyi GN. Slamon DJ, et al. Ther Adv Med Oncol. 2023 May 29;15:17588359231178125. doi: 10.1177/17588359231178125. eCollection 2023. Ther Adv Med Oncol. 2023. PMID: 37275963 Free PMC article.
New Adjuvant Trial with Ribociclib [LEE011] (NATALEE) is a trial evaluating the efficacy and safety of adjuvant ribociclib plus endocrine therapy (ET) versus ET alone in patients with HR+/HER2- early nonmetastatic breast cancer (EBC). ...Patients undergo 1:1 randomization …
New Adjuvant Trial with Ribociclib [LEE011] (NATALEE) is a trial evaluating the efficacy and safety of adjuvant ribociclib plus endocrine th …
Updates on obesity and the obesity paradox in cardiovascular diseases.
Tutor AW, Lavie CJ, Kachur S, Milani RV, Ventura HO. Tutor AW, et al. Prog Cardiovasc Dis. 2023 May-Jun;78:2-10. doi: 10.1016/j.pcad.2022.11.013. Epub 2022 Dec 5. Prog Cardiovasc Dis. 2023. PMID: 36481212 Review.
Surprisingly, similar data has also shown that cardiovascular fitness, rather than weight loss alone, influences the relationship between obesity and mortality in those with established CVD. ...
Surprisingly, similar data has also shown that cardiovascular fitness, rather than weight loss alone, influences the relationship bet …
Hormone Therapy and Other Treatments for Symptoms of Menopause.
Hill DA, Crider M, Hill SR. Hill DA, et al. Am Fam Physician. 2016 Dec 1;94(11):884-889. Am Fam Physician. 2016. PMID: 27929271 Free article. Review.
In the past, physicians prescribed hormone therapy to improve overall health and prevent cardiac disease, as well as for symptoms of menopause. Combined estrogen/progestogen therapy, but not estrogen alone, increases the risk of breast cancer when used for more than three …
In the past, physicians prescribed hormone therapy to improve overall health and prevent cardiac disease, as well as for symptoms of menopau …
Akinesia.
Ramakrishnan S, De Jesus O. Ramakrishnan S, et al. 2023 Aug 28. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan–. 2023 Aug 28. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan–. PMID: 32965848 Free Books & Documents.
Akinetic states are associated with numerous etiological causes, that vary with the age of the patient. In adults, akinesia can present alone or as sequelae of neurodegenerative disorders. Findings of akinesia noticed antenatally or neonatally is associated with fetal akin …
Akinetic states are associated with numerous etiological causes, that vary with the age of the patient. In adults, akinesia can present a
Ileus.
Beach EC, De Jesus O. Beach EC, et al. 2023 Aug 23. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan–. 2023 Aug 23. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan–. PMID: 32644363 Free Books & Documents.
Due to the delayed refeeding syndrome seen after an ileus, postoperative ileus has a large economic impact in the United States alone. An ileus usually manifests itself from the third to the fifth day after surgery and usually lasts 2 to 3 days with the small bowel being t …
Due to the delayed refeeding syndrome seen after an ileus, postoperative ileus has a large economic impact in the United States alone
Palbociclib with adjuvant endocrine therapy in early breast cancer (PALLAS): interim analysis of a multicentre, open-label, randomised, phase 3 study.
Mayer EL, Dueck AC, Martin M, Rubovszky G, Burstein HJ, Bellet-Ezquerra M, Miller KD, Zdenkowski N, Winer EP, Pfeiler G, Goetz M, Ruiz-Borrego M, Anderson D, Nowecki Z, Loibl S, Moulder S, Ring A, Fitzal F, Traina T, Chan A, Rugo HS, Lemieux J, Henao F, Lyss A, Antolin Novoa S, Wolff AC, Vetter M, Egle D, Morris PG, Mamounas EP, Gil-Gil MJ, Prat A, Fohler H, Metzger Filho O, Schwarz M, DuFrane C, Fumagalli D, Theall KP, Lu DR, Bartlett CH, Koehler M, Fesl C, DeMichele A, Gnant M. Mayer EL, et al. Lancet Oncol. 2021 Feb;22(2):212-222. doi: 10.1016/S1470-2045(20)30642-2. Epub 2021 Jan 15. Lancet Oncol. 2021. PMID: 33460574 Clinical Trial.
FINDINGS: Between Sept 1, 2015, and Nov 30, 2018, 5760 patients were randomly assigned to receive palbociclib plus endocrine therapy (n=2883) or endocrine therapy alone (n=2877). At the time of the planned second interim analysis, at a median follow-up of 23.7 months (IQR …
FINDINGS: Between Sept 1, 2015, and Nov 30, 2018, 5760 patients were randomly assigned to receive palbociclib plus endocrine therapy (n=2883 …
Intra-Articular Injection of BPC 157 for Multiple Types of Knee Pain.
Lee E, Padgett B. Lee E, et al. Altern Ther Health Med. 2021 Jul;27(4):8-13. Altern Ther Health Med. 2021. PMID: 34324435
METHODS: A retrospective study was done at the Institute for Hormonal Balance in Orlando, Florida, USA to see whether intra-articular injection of the peptide BPC 157, alone or combined with TB4, helped relieve knee pain. ...
METHODS: A retrospective study was done at the Institute for Hormonal Balance in Orlando, Florida, USA to see whether intra-articular …
NSABP B-47/NRG Oncology Phase III Randomized Trial Comparing Adjuvant Chemotherapy With or Without Trastuzumab in High-Risk Invasive Breast Cancer Negative for HER2 by FISH and With IHC 1+ or 2.
Fehrenbacher L, Cecchini RS, Geyer CE Jr, Rastogi P, Costantino JP, Atkins JN, Crown JP, Polikoff J, Boileau JF, Provencher L, Stokoe C, Moore TD, Robidoux A, Flynn PJ, Borges VF, Albain KS, Swain SM, Paik S, Mamounas EP, Wolmark N. Fehrenbacher L, et al. J Clin Oncol. 2020 Feb 10;38(5):444-453. doi: 10.1200/JCO.19.01455. Epub 2019 Dec 10. J Clin Oncol. 2020. PMID: 31821109 Free PMC article. Clinical Trial.
RESULTS: At a median follow-up of 46 months, the addition of trastuzumab to CRx did not improve IDFS (5-year IDFS: 89.8% with CRx plus trastuzumab [CRxT] v 89.2% with CRx alone; hazard ratio [HR], 0.98; 95% CI, 0.76 to 1.25; P = .85). These findings did not differ by level …
RESULTS: At a median follow-up of 46 months, the addition of trastuzumab to CRx did not improve IDFS (5-year IDFS: 89.8% with CRx plus trast …
Ultrasound imaging of diaphragmatic motion.
May LA, Epelman M, Navarro OM. May LA, et al. Pediatr Radiol. 2022 Sep;52(10):2051-2061. doi: 10.1007/s00247-022-05430-7. Epub 2022 Jul 2. Pediatr Radiol. 2022. PMID: 35778573 Review.
Diaphragmatic dysfunction and paralysis can have significant implications for medical management and treatment, and they can be challenging to diagnose by clinical parameters alone. Multiple imaging modalities are useful for assessing the diaphragm, but US - specifically M …
Diaphragmatic dysfunction and paralysis can have significant implications for medical management and treatment, and they can be challenging …
Physical relaxation for occupational stress in healthcare workers: A systematic review and network meta-analysis of randomized controlled trials.
Zhang M, Murphy B, Cabanilla A, Yidi C. Zhang M, et al. J Occup Health. 2021 Jan;63(1):e12243. doi: 10.1002/1348-9585.12243. J Occup Health. 2021. PMID: 34235817 Free PMC article.

Random-effects meta-analysis shows that physical relaxation methods overall reduced measures of occupational stress at the longest duration of follow-up vs baseline compared to non-intervention controls (SMD -0.53; 95% CI [-0.74 to -0.33]; p < .00001). On network meta-analysis

Random-effects meta-analysis shows that physical relaxation methods overall reduced measures of occupational stress at the longest duration …
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