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Genome-wide mega-analysis identifies 16 loci and highlights diverse biological mechanisms in the common epilepsies.
Nat Commun. 2018 Dec 10;9(1):5269. doi: 10.1038/s41467-018-07524-z.
Nat Commun. 2018.
PMID: 30531953
Free PMC article.
GWAS meta-analysis of over 29,000 people with epilepsy identifies 26 risk loci and subtype-specific genetic architecture.
International League Against Epilepsy Consortium on Complex Epilepsies.
International League Against Epilepsy Consortium on Complex Epilepsies.
Nat Genet. 2023 Sep;55(9):1471-1482. doi: 10.1038/s41588-023-01485-w. Epub 2023 Aug 31.
Nat Genet. 2023.
PMID: 37653029
Free PMC article.
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Shared genetic basis between genetic generalized epilepsy and background electroencephalographic oscillations.
Stevelink R, Luykx JJ, Lin BD, Leu C, Lal D, Smith AW, Schijven D, Carpay JA, Rademaker K, Rodrigues Baldez RA, Devinsky O, Braun KPJ, Jansen FE, Smit DJA, Koeleman BPC; International League Against Epilepsy Consortium on Complex Epilepsies; Epi25 Collaborative.
Stevelink R, et al.
Epilepsia. 2021 Jul;62(7):1518-1527. doi: 10.1111/epi.16922. Epub 2021 May 18.
Epilepsia. 2021.
PMID: 34002374
Free PMC article.
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Analysis of shared common genetic risk between amyotrophic lateral sclerosis and epilepsy.
Schijven D, Stevelink R, McCormack M, van Rheenen W, Luykx JJ, Koeleman BPC, Veldink JH; Project MinE ALS GWAS Consortium; International League Against Epilepsy Consortium on Complex Epilepsies.
Schijven D, et al.
Neurobiol Aging. 2020 Aug;92:153.e1-153.e5. doi: 10.1016/j.neurobiolaging.2020.04.011. Epub 2020 Apr 18.
Neurobiol Aging. 2020.
PMID: 32409253
Free PMC article.
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Vorapaxar in the secondary prevention of atherothrombotic events.
Morrow DA, Braunwald E, Bonaca MP, Ameriso SF, Dalby AJ, Fish MP, Fox KA, Lipka LJ, Liu X, Nicolau JC, Ophuis AJ, Paolasso E, Scirica BM, Spinar J, Theroux P, Wiviott SD, Strony J, Murphy SA; TRA 2P–TIMI 50 Steering Committee and Investigators.
Morrow DA, et al.
N Engl J Med. 2012 Apr 12;366(15):1404-13. doi: 10.1056/NEJMoa1200933. Epub 2012 Mar 24.
N Engl J Med. 2012.
PMID: 22443427
Free article.
Clinical Trial.
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Genetic determinants of common epilepsies: a meta-analysis of genome-wide association studies.
International League Against Epilepsy Consortium on Complex Epilepsies. Electronic address: epilepsy-austin@unimelb.edu.au.
International League Against Epilepsy Consortium on Complex Epilepsies. Electronic address: epilepsy-austin@unimelb.edu.au.
Lancet Neurol. 2014 Sep;13(9):893-903. doi: 10.1016/S1474-4422(14)70171-1. Epub 2014 Jul 30.
Lancet Neurol. 2014.
PMID: 25087078
Free PMC article.
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Assessing the genetic association between vitamin B6 metabolism and genetic generalized epilepsy.
Stevelink R, Pangilinan F, Jansen FE, Braun KPJ; International League Against Epilepsy Consortium on Complex Epilepsies; Molloy AM, Brody LC, Koeleman BPC.
Stevelink R, et al.
Mol Genet Metab Rep. 2019 Oct 11;21:100518. doi: 10.1016/j.ymgmr.2019.100518. eCollection 2019 Dec.
Mol Genet Metab Rep. 2019.
PMID: 31641590
Free PMC article.
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