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Continuous evolution of base editors with expanded target compatibility and improved activity.
Nat Biotechnol. 2019 Sep;37(9):1070-1079. doi: 10.1038/s41587-019-0193-0. Epub 2019 Jul 22.
Nat Biotechnol. 2019.
PMID: 31332326
Free PMC article.
Emerging Gene Therapies for Genetic Hearing Loss.
Ahmed H, Shubina-Oleinik O, Holt JR.
Ahmed H, et al. Among authors: shubina oleinik o.
J Assoc Res Otolaryngol. 2017 Oct;18(5):649-670. doi: 10.1007/s10162-017-0634-8. Epub 2017 Aug 16.
J Assoc Res Otolaryngol. 2017.
PMID: 28815315
Free PMC article.
Review.
Item in Clipboard
Optimized AAV Vectors for TMC1 Gene Therapy in a Humanized Mouse Model of DFNB7/11.
Marcovich I, Baer NK, Shubina-Oleinik O, Eclov R, Beard CW, Holt JR.
Marcovich I, et al. Among authors: shubina oleinik o.
Biomolecules. 2022 Jun 29;12(7):914. doi: 10.3390/biom12070914.
Biomolecules. 2022.
PMID: 35883470
Free PMC article.
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Single and Dual Vector Gene Therapy with AAV9-PHP.B Rescues Hearing in Tmc1 Mutant Mice.
Wu J, Solanes P, Nist-Lund C, Spataro S, Shubina-Oleinik O, Marcovich I, Goldberg H, Schneider BL, Holt JR.
Wu J, et al. Among authors: shubina oleinik o.
Mol Ther. 2021 Mar 3;29(3):973-988. doi: 10.1016/j.ymthe.2020.11.016. Epub 2020 Nov 17.
Mol Ther. 2021.
PMID: 33212302
Free PMC article.
Item in Clipboard
Dual-vector gene therapy restores cochlear amplification and auditory sensitivity in a mouse model of DFNB16 hearing loss.
Shubina-Oleinik O, Nist-Lund C, French C, Rockowitz S, Shearer AE, Holt JR.
Shubina-Oleinik O, et al.
Sci Adv. 2021 Dec 17;7(51):eabi7629. doi: 10.1126/sciadv.abi7629. Epub 2021 Dec 15.
Sci Adv. 2021.
PMID: 34910522
Free PMC article.
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In vivo base editing restores sensory transduction and transiently improves auditory function in a mouse model of recessive deafness.
Yeh WH, Shubina-Oleinik O, Levy JM, Pan B, Newby GA, Wornow M, Burt R, Chen JC, Holt JR, Liu DR.
Yeh WH, et al. Among authors: shubina oleinik o.
Sci Transl Med. 2020 Jun 3;12(546):eaay9101. doi: 10.1126/scitranslmed.aay9101.
Sci Transl Med. 2020.
PMID: 32493795
Free PMC article.
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Publisher Correction: Continuous evolution of base editors with expanded target compatibility and improved activity.
Thuronyi BW, Koblan LW, Levy JM, Yeh WH, Zheng C, Newby GA, Wilson C, Bhaumik M, Shubina-Oleinik O, Holt JR, Liu DR.
Thuronyi BW, et al. Among authors: shubina oleinik o.
Nat Biotechnol. 2019 Sep;37(9):1091. doi: 10.1038/s41587-019-0253-5.
Nat Biotechnol. 2019.
PMID: 31406330
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