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Loss of cardiomyocyte CYB5R3 impairs redox equilibrium and causes sudden cardiac death.
Carew NT, Schmidt HM, Yuan S, Galley JC, Hall R, Altmann HM, Hahn SA, Miller MP, Wood KC, Gabris B, Stapleton MC, Hartwick S, Fazzari M, Wu YL, Trebak M, Kaufman BA, McTiernan CF, Schopfer FJ, Navas P, Thibodeau PH, McNamara DM, Salama G, Straub AC. Carew NT, et al. J Clin Invest. 2022 Sep 15;132(18):e147120. doi: 10.1172/JCI147120. J Clin Invest. 2022. PMID: 36106636 Free PMC article.
Cytochrome b5 Reductase 3 Modulates Soluble Guanylate Cyclase Redox State and cGMP Signaling.
Rahaman MM, Nguyen AT, Miller MP, Hahn SA, Sparacino-Watkins C, Jobbagy S, Carew NT, Cantu-Medellin N, Wood KC, Baty CJ, Schopfer FJ, Kelley EE, Gladwin MT, Martin E, Straub AC. Rahaman MM, et al. Among authors: carew nt. Circ Res. 2017 Jul 7;121(2):137-148. doi: 10.1161/CIRCRESAHA.117.310705. Epub 2017 Jun 5. Circ Res. 2017. PMID: 28584062 Free PMC article.