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The kynurenic acid analog SZR104 induces cytomorphological changes associated with the anti-inflammatory phenotype in cultured microglia.
Sci Rep. 2023 Jul 13;13(1):11328. doi: 10.1038/s41598-023-38107-8.
Sci Rep. 2023.
PMID: 37443330
Free PMC article.
Kynurenic Acid and Its Analog SZR104 Exhibit Strong Antiinflammatory Effects and Alter the Intracellular Distribution and Methylation Patterns of H3 Histones in Immunochallenged Microglia-Enriched Cultures of Newborn Rat Brains.
Szabo M, Lajkó N, Dulka K, Szatmári I, Fülöp F, Mihály A, Vécsei L, Gulya K.
Szabo M, et al. Among authors: lajko n.
Int J Mol Sci. 2022 Jan 19;23(3):1079. doi: 10.3390/ijms23031079.
Int J Mol Sci. 2022.
PMID: 35163002
Free PMC article.
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Epigenetic Consequences of in Utero Exposure to Rosuvastatin: Alteration of Histone Methylation Patterns in Newborn Rat Brains.
Dulka K, Szabo M, Lajkó N, Belecz I, Hoyk Z, Gulya K.
Dulka K, et al. Among authors: lajko n.
Int J Mol Sci. 2021 Mar 26;22(7):3412. doi: 10.3390/ijms22073412.
Int J Mol Sci. 2021.
PMID: 33810299
Free PMC article.
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Quantitative morphometric and cell-type-specific population analysis of microglia-enriched cultures subcloned to high purity from newborn rat brains.
Dulka K, Nacsa K, Lajkó N, Gulya K.
Dulka K, et al. Among authors: lajko n.
IBRO Neurosci Rep. 2021 Feb 6;10:119-129. doi: 10.1016/j.ibneur.2021.01.007. eCollection 2021 Jun.
IBRO Neurosci Rep. 2021.
PMID: 33842918
Free PMC article.
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Sensitivity of Rodent Microglia to Kynurenines in Models of Epilepsy and Inflammation In Vivo and In Vitro: Microglia Activation is Inhibited by Kynurenic Acid and the Synthetic Analogue SZR104.
Lajkó N, Kata D, Szabó M, Mátyás A, Dulka K, Földesi I, Fülöp F, Gulya K, Vécsei L, Mihály A.
Lajkó N, et al.
Int J Mol Sci. 2020 Dec 7;21(23):9333. doi: 10.3390/ijms21239333.
Int J Mol Sci. 2020.
PMID: 33297593
Free PMC article.
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Opposite and Differently Altered Postmortem Changes in H3 and H3K9me3 Patterns in the Rat Frontal Cortex and Hippocampus.
Dulka K, Lajkó N, Nacsa K, Gulya K.
Dulka K, et al. Among authors: lajko n.
Epigenomes. 2024 Mar 18;8(1):11. doi: 10.3390/epigenomes8010011.
Epigenomes. 2024.
PMID: 38534795
Free PMC article.
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