Therapeutic Zfra4-10 or WWOX7-21 Peptide Induces Complex Formation of WWOX with Selective Protein Targets in Organs that Leads to Cancer Suppression and Spleen Cytotoxic Memory Z Cell Activation In Vivo.
Su WP, Wang WJ, Chang JY, Ho PC, Liu TY, Wen KY, Kuo HL, Chen YJ, Huang SS, Subhan D, Chen YA, Lu CY, Wu CY, Lin SR, Lee MH, Chiang MF, Sze CI, Chang NS.
Su WP, et al.
Cancers (Basel). 2020 Aug 5;12(8):2189. doi: 10.3390/cancers12082189.
Cancers (Basel). 2020.
PMID: 32764489
Free PMC article.
In addition to Zfra4-10 and WWOX7-21 peptides, stimulating the membrane Hyal-2/WWOX complex with Hyal-2 antibody and sonicated hyaluronan (HAson) induced Z cell activation for killing cancer cells in vivo and in vitro. Mechanistically, Zfra4-10 binds to membrane Hyal-2, in …
In addition to Zfra4-10 and WWOX7-21 peptides, stimulating the membrane Hyal-2/WWOX complex with Hyal-2 antibody and sonicated hyaluronan ( …