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A synthetic agent ameliorates polycystic kidney disease by promoting apoptosis of cystic cells through increased oxidative stress.
Fedeles BI, Bhardwaj R, Ishikawa Y, Khumsubdee S, Krappitz M, Gubina N, Volpe I, Andrade DC, Westergerling P, Staudner T, Campolo J, Liu SS, Dong K, Cai Y, Rehman M, Gallagher AR, Ruchirawat S, Croy RG, Essigmann JM, Fedeles SV, Somlo S. Fedeles BI, et al. Among authors: gubina n. Proc Natl Acad Sci U S A. 2024 Jan 23;121(4):e2317344121. doi: 10.1073/pnas.2317344121. Epub 2024 Jan 19. Proc Natl Acad Sci U S A. 2024. PMID: 38241440 Free PMC article.
Random Copolymers of Lysine and Isoleucine for Efficient mRNA Delivery.
Pilipenko I, Korovkina O, Gubina N, Ekimova V, Ishutinova A, Korzhikova-Vlakh E, Tennikova T, Korzhikov-Vlakh V. Pilipenko I, et al. Among authors: gubina n. Int J Mol Sci. 2022 May 11;23(10):5363. doi: 10.3390/ijms23105363. Int J Mol Sci. 2022. PMID: 35628177 Free PMC article.
7,8-Dihydro-8-oxo-1,N6-ethenoadenine: an exclusively Hoogsteen-paired thymine mimic in DNA that induces A→T transversions in Escherichia coli.
Aralov AV, Gubina N, Cabrero C, Tsvetkov VB, Turaev AV, Fedeles BI, Croy RG, Isaakova EA, Melnik D, Dukova S, Ryazantsev DY, Khrulev AA, Varizhuk AM, González C, Zatsepin TS, Essigmann JM. Aralov AV, et al. Among authors: gubina n. Nucleic Acids Res. 2022 Apr 8;50(6):3056-3069. doi: 10.1093/nar/gkac148. Nucleic Acids Res. 2022. PMID: 35234900 Free PMC article.
Mitochondrial ROS Produced via Reverse Electron Transport Extend Animal Lifespan.
Scialò F, Sriram A, Fernández-Ayala D, Gubina N, Lõhmus M, Nelson G, Logan A, Cooper HM, Navas P, Enríquez JA, Murphy MP, Sanz A. Scialò F, et al. Among authors: gubina n. Cell Metab. 2016 Apr 12;23(4):725-34. doi: 10.1016/j.cmet.2016.03.009. Cell Metab. 2016. PMID: 27076081 Free PMC article.