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Genome-wide epigenetic and mRNA-expression profiling followed by CRISPR/Cas9-mediated gene-disruptions corroborate the MIR141/MIR200C-ZEB1/ZEB2-FGFR1 axis in acquired EMT-associated EGFR TKI-resistance in NSCLC cells.
Vad-Nielsen J, Staunstrup NH, Kjeldsen ML, Dybdal N, Flandin G, De Stradis C, Daugaard TF, Vilsbøll-Larsen T, Maansson CT, Doktor TK, Sorensen BS, Nielsen AL. Vad-Nielsen J, et al. Among authors: dybdal n. Transl Lung Cancer Res. 2023 Jan 31;12(1):42-65. doi: 10.21037/tlcr-22-507. Epub 2023 Jan 13. Transl Lung Cancer Res. 2023. PMID: 36762066 Free PMC article.