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Identification and characterization of a MAPT-targeting locked nucleic acid antisense oligonucleotide therapeutic for tauopathies.
Easton A, Jensen ML, Wang C, Hagedorn PH, Li Y, Weed M, Meredith JE, Guss V, Jones K, Gill M, Krause C, Brown JM, Hunihan L, Natale J, Fernandes A, Lu Y, Polino J, Bookbinder M, Cadelina G, Benitex Y, Sane R, Morrison J, Drexler D, Mercer SE, Bon C, Pandya NJ, Jagasia R, Ou Yang TH, Distler T, Grüninger F, Meldgaard M, Terrigno M, Macor JE, Albright CF, Loy J, Hoeg AM, Olson RE, Cacace AM. Easton A, et al. Among authors: pandya nj. Mol Ther Nucleic Acids. 2022 Aug 4;29:625-642. doi: 10.1016/j.omtn.2022.07.027. eCollection 2022 Sep 13. Mol Ther Nucleic Acids. 2022. PMID: 36090761 Free PMC article.
Inducers of the endothelial cell barrier identified through chemogenomic screening in genome-edited hPSC-endothelial cells.
Roudnicky F, Zhang JD, Kim BK, Pandya NJ, Lan Y, Sach-Peltason L, Ragelle H, Strassburger P, Gruener S, Lazendic M, Uhles S, Revelant F, Eidam O, Sturm G, Kueppers V, Christensen K, Goldstein LD, Tzouros M, Banfai B, Modrusan Z, Graf M, Patsch C, Burcin M, Meyer CA, Westenskow PD, Cowan CA. Roudnicky F, et al. Among authors: pandya nj. Proc Natl Acad Sci U S A. 2020 Aug 18;117(33):19854-19865. doi: 10.1073/pnas.1911532117. Epub 2020 Aug 5. Proc Natl Acad Sci U S A. 2020. PMID: 32759214 Free PMC article.
Noelin1 Affects Lateral Mobility of Synaptic AMPA Receptors.
Pandya NJ, Seeger C, Babai N, Gonzalez-Lozano MA, Mack V, Lodder JC, Gouwenberg Y, Mansvelder HD, Danielson UH, Li KW, Heine M, Spijker S, Frischknecht R, Smit AB. Pandya NJ, et al. Cell Rep. 2018 Jul 31;24(5):1218-1230. doi: 10.1016/j.celrep.2018.06.102. Cell Rep. 2018. PMID: 30067977 Free PMC article.
Secreted retrovirus-like GAG-domain-containing protein PEG10 is regulated by UBE3A and is involved in Angelman syndrome pathophysiology.
Pandya NJ, Wang C, Costa V, Lopatta P, Meier S, Zampeta FI, Punt AM, Mientjes E, Grossen P, Distler T, Tzouros M, Martí Y, Banfai B, Patsch C, Rasmussen S, Hoener M, Berrera M, Kremer T, Dunkley T, Ebeling M, Distel B, Elgersma Y, Jagasia R. Pandya NJ, et al. Cell Rep Med. 2021 Aug 17;2(8):100360. doi: 10.1016/j.xcrm.2021.100360. eCollection 2021 Aug 17. Cell Rep Med. 2021. PMID: 34467244 Free PMC article.
Evaluation of bovine milk extracellular vesicles for the delivery of locked nucleic acid antisense oligonucleotides.
Grossen P, Portmann M, Koller E, Duschmalé M, Minz T, Sewing S, Pandya NJ, van Geijtenbeek SK, Ducret A, Kusznir EA, Huber S, Berrera M, Lauer ME, Ringler P, Nordbo B, Jensen ML, Sladojevich F, Jagasia R, Alex R, Gamboni R, Keller M. Grossen P, et al. Eur J Pharm Biopharm. 2021 Jan;158:198-210. doi: 10.1016/j.ejpb.2020.11.012. Epub 2020 Nov 26. Eur J Pharm Biopharm. 2021. PMID: 33248268
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