Complex Vascular Resections for Retroperitoneal Soft Tissue Sarcoma

Curr Oncol. 2023 Mar 20;30(3):3500-3515. doi: 10.3390/curroncol30030266.

Abstract

Retroperitoneal sarcomas (RPSs) are locally aggressive tumors that can compromise major vessels of the retroperitoneum including the inferior vena cava, aorta, or main tributary vessels. Vascular involvement can be secondary to the tumor's infiltrating growth pattern or primary vascular origin. Surgery is still the mainstay for curing this disease, and resection of RPSs may include major vascular resections to secure adequate oncologic results. Our improved knowledge in the tumor biology of RPSs, in conjunction with the growing surgical expertise in both sarcoma and vascular surgical techniques, has allowed for major vascular reconstructions within multi-visceral resections for RPSs with good perioperative results. This complex surgical approach may include the combined work of various surgical subspecialties.

Keywords: oncovascular surgery; retroperitoneum; sarcoma; vascular reconstruction.

Publication types

  • Review

MeSH terms

  • Humans
  • Retroperitoneal Neoplasms* / pathology
  • Retroperitoneal Neoplasms* / surgery
  • Sarcoma* / pathology
  • Sarcoma* / surgery
  • Treatment Outcome
  • Vena Cava, Inferior / pathology
  • Vena Cava, Inferior / surgery

Grants and funding

This research received no external funding.