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Page 1
Gold(I) Bis(1,2,3-triazol-5-ylidene) Complexes as Promising Selective Anticancer Compounds.
J Med Chem. 2021 Nov 11;64(21):15747-15757. doi: 10.1021/acs.jmedchem.1c01021. Epub 2021 Oct 20.
J Med Chem. 2021.
PMID: 34670090
Novel gold(I) complexes induce apoptosis in leukemia cells via the ROS-induced mitochondrial pathway with an upregulation of Harakiri and overcome multi drug resistances in leukemia and lymphoma cells and sensitize drug resistant tumor cells to apoptosis in vitro.
Ahrweiler-Sawaryn MC, Biswas A, Frias C, Frias J, Wilke NL, Wilke N, Berkessel A, Prokop A.
Ahrweiler-Sawaryn MC, et al. Among authors: wilke nl.
Biomed Pharmacother. 2023 May;161:114507. doi: 10.1016/j.biopha.2023.114507. Epub 2023 Mar 21.
Biomed Pharmacother. 2023.
PMID: 36958194
Free article.
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Ruthenium Complex HB324 Induces Apoptosis via Mitochondrial Pathway with an Upregulation of Harakiri and Overcomes Cisplatin Resistance in Neuroblastoma Cells In Vitro.
Wilke NL, Burmeister H, Frias C, Ott I, Prokop A.
Wilke NL, et al.
Int J Mol Sci. 2023 Jan 4;24(2):952. doi: 10.3390/ijms24020952.
Int J Mol Sci. 2023.
PMID: 36674465
Free PMC article.
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The gallium complex KP46 sensitizes resistant leukemia cells and overcomes Bcl-2-induced multidrug resistance in lymphoma cells via upregulation of Harakiri and downregulation of XIAP in vitro.
Wilke NL, Abodo LO, Frias C, Frias J, Baas J, Jakupec MA, Keppler BK, Prokop A.
Wilke NL, et al.
Biomed Pharmacother. 2022 Dec;156:113974. doi: 10.1016/j.biopha.2022.113974. Epub 2022 Nov 5.
Biomed Pharmacother. 2022.
PMID: 36411649
Free article.
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