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Page 1
Structural basis for ligase-specific conjugation of linear ubiquitin chains by HOIP.
Stieglitz B, Rana RR, Koliopoulos MG, Morris-Davies AC, Schaeffer V, Christodoulou E, Howell S, Brown NR, Dikic I, Rittinger K. Stieglitz B, et al. Among authors: brown nr. Nature. 2013 Nov 21;503(7476):422-426. doi: 10.1038/nature12638. Epub 2013 Oct 20. Nature. 2013. PMID: 24141947 Free PMC article.
A new crystal form of Lys48-linked diubiquitin.
Trempe JF, Brown NR, Noble ME, Endicott JA. Trempe JF, et al. Among authors: brown nr. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010 Sep 1;66(Pt 9):994-8. doi: 10.1107/S1744309110027600. Epub 2010 Aug 21. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010. PMID: 20823512 Free PMC article.
Restoring p53 function in human melanoma cells by inhibiting MDM2 and cyclin B1/CDK1-phosphorylated nuclear iASPP.
Lu M, Breyssens H, Salter V, Zhong S, Hu Y, Baer C, Ratnayaka I, Sullivan A, Brown NR, Endicott J, Knapp S, Kessler BM, Middleton MR, Siebold C, Jones EY, Sviderskaya EV, Cebon J, John T, Caballero OL, Goding CR, Lu X. Lu M, et al. Among authors: brown nr. Cancer Cell. 2013 May 13;23(5):618-33. doi: 10.1016/j.ccr.2013.03.013. Epub 2013 Apr 25. Cancer Cell. 2013. PMID: 23623661 Free article.
Restoring p53 Function in Human Melanoma Cells by Inhibiting MDM2 and Cyclin B1/CDK1-Phosphorylated Nuclear iASPP.
Lu M, Breyssens H, Salter V, Zhong S, Hu Y, Baer C, Ratnayaka I, Sullivan A, Brown NR, Endicott J, Knapp S, Kessler BM, Middleton MR, Siebold C, Jones EY, Sviderskaya EV, Cebon J, John T, Caballero OL, Goding CR, Lu X. Lu M, et al. Among authors: brown nr. Cancer Cell. 2016 Nov 14;30(5):822-823. doi: 10.1016/j.ccell.2016.09.019. Cancer Cell. 2016. PMID: 27846394 Free article. No abstract available.