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Year Number of Results
2019 4
2020 3
2021 1
2022 2
2023 1
2024 3

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13 results

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Page 1
Internal checkpoint regulates T cell neoantigen reactivity and susceptibility to PD1 blockade.
Palmer DC, Webber BR, Patel Y, Johnson MJ, Kariya CM, Lahr WS, Parkhurst MR, Gartner JJ, Prickett TD, Lowery FJ, Kishton RJ, Gurusamy D, Franco Z, Vodnala SK, Diers MD, Wolf NK, Slipek NJ, McKenna DH, Sumstad D, Viney L, Henley T, Bürckstümmer T, Baker O, Hu Y, Yan C, Meerzaman D, Padhan K, Lo W, Malekzadeh P, Jia L, Deniger DC, Patel SJ, Robbins PF, McIvor RS, Choudhry M, Rosenberg SA, Moriarity BS, Restifo NP. Palmer DC, et al. Among authors: slipek nj. Med. 2022 Oct 14;3(10):682-704.e8. doi: 10.1016/j.medj.2022.07.008. Epub 2022 Aug 24. Med. 2022. PMID: 36007524 Free PMC article.
Cas9-induced targeted integration of large DNA payloads in primary human T cells via homology-mediated end-joining DNA repair.
Webber BR, Johnson MJ, Skeate JG, Slipek NJ, Lahr WS, DeFeo AP, Mills LJ, Qiu X, Rathmann B, Diers MD, Wick B, Henley T, Choudhry M, Starr TK, McIvor RS, Moriarity BS. Webber BR, et al. Among authors: slipek nj. Nat Biomed Eng. 2023 Dec 13. doi: 10.1038/s41551-023-01157-4. Online ahead of print. Nat Biomed Eng. 2023. PMID: 38092857
SEMA4C is a novel target to limit osteosarcoma growth, progression, and metastasis.
Smeester BA, Slipek NJ, Pomeroy EJ, Bomberger HE, Shamsan GA, Peterson JJ, Crosby MR, Draper GM, Becklin KL, Rahrmann EP, McCarthy JB, Odde DJ, Wood DK, Largaespada DA, Moriarity BS. Smeester BA, et al. Among authors: slipek nj. Oncogene. 2020 Jan;39(5):1049-1062. doi: 10.1038/s41388-019-1041-x. Epub 2019 Oct 3. Oncogene. 2020. PMID: 31582836
CRISPR-Cas9 cytidine and adenosine base editing of splice-sites mediates highly-efficient disruption of proteins in primary and immortalized cells.
Kluesner MG, Lahr WS, Lonetree CL, Smeester BA, Qiu X, Slipek NJ, Claudio Vázquez PN, Pitzen SP, Pomeroy EJ, Vignes MJ, Lee SC, Bingea SP, Andrew AA, Webber BR, Moriarity BS. Kluesner MG, et al. Among authors: slipek nj. Nat Commun. 2021 Apr 23;12(1):2437. doi: 10.1038/s41467-021-22009-2. Nat Commun. 2021. PMID: 33893286 Free PMC article.
PLX3397 treatment inhibits constitutive CSF1R-induced oncogenic ERK signaling, reduces tumor growth, and metastatic burden in osteosarcoma.
Smeester BA, Slipek NJ, Pomeroy EJ, Laoharawee K, Osum SH, Larsson AT, Williams KB, Stratton N, Yamamoto K, Peterson JJ, Rathe SK, Mills LJ, Hudson WA, Crosby MR, Wang M, Rahrmann EP, Moriarity BS, Largaespada DA. Smeester BA, et al. Among authors: slipek nj. Bone. 2020 Jul;136:115353. doi: 10.1016/j.bone.2020.115353. Epub 2020 Apr 3. Bone. 2020. PMID: 32251854
Implication of ZNF217 in Accelerating Tumor Development and Therapeutically Targeting ZNF217-Induced PI3K-AKT Signaling for the Treatment of Metastatic Osteosarcoma.
Smeester BA, Draper GM, Slipek NJ, Larsson AT, Stratton N, Pomeroy EJ, Becklin KL, Yamamoto K, Williams KB, Laoharawee K, Peterson JJ, Abrahante JE, Rathe SK, Mills LJ, Crosby MR, Hudson WA, Rahrmann EP, Largaespada DA, Moriarity BS. Smeester BA, et al. Among authors: slipek nj. Mol Cancer Ther. 2020 Dec;19(12):2528-2541. doi: 10.1158/1535-7163.MCT-20-0369. Epub 2020 Sep 30. Mol Cancer Ther. 2020. PMID: 32999043 Free PMC article.
13 results