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The following term was not found in PubMed: Ozdoner
Page 1
Efficacy and Safety of Nebivolol and Rosuvastatin Combination Treatment in Patients with Concomitant Hypertension and Hyperlipidemia.
Rhee MY, Kim CH, Ahn Y, Shin JH, Han SH, Kang HJ, Hong SJ, Kim HY. Rhee MY, et al. Drug Des Devel Ther. 2020 Nov 17;14:5005-5017. doi: 10.2147/DDDT.S280055. eCollection 2020. Drug Des Devel Ther. 2020. PMID: 33235439 Free PMC article. Clinical Trial.
The percent reduction in low-density lipoprotein (LDL) cholesterol differed between the NEBI/RSV and NEBI groups (LSmean difference = -47.76%, 95% CI = -52.69 to -42.84%) but not between the NEBI/RSV and RSV groups. ...The LDL cholesterol goal achievement rat …
The percent reduction in low-density lipoprotein (LDL) cholesterol differed between the NEBI/RSV and NEBI groups (LSmean diffe …
pH-Sensitive, N-ethoxybenzylimidazole (NEBI) bifunctional crosslinkers enable triggered release of therapeutics from drug delivery carriers.
Luong A, Issarapanichkit T, Kong SD, Fong R, Yang J. Luong A, et al. Org Biomol Chem. 2010 Nov 21;8(22):5105-9. doi: 10.1039/c0ob00228c. Epub 2010 Sep 6. Org Biomol Chem. 2010. PMID: 20820656
Fluorescence imaging and cell viability studies demonstrate that the HSA-NEBI-doxorubicin conjugate exhibited improved uptake and cytotoxic activity compared to the unconjugated doxorubicin analog. The pH-sensitive NEBI group was also shown to be relatively stable t …
Fluorescence imaging and cell viability studies demonstrate that the HSA-NEBI-doxorubicin conjugate exhibited improved uptake and cyt …
Association of Renin Angiotensin Aldosterone System Inhibitors and Outcomes of Hospitalized Patients With COVID-19.
Gupta N, Settle L, Brown BR, Armaignac DL, Baram M, Perkins NE, Kaufman M, Melamed RR, Christie AB, Danesh VC, Denson JL, Cheruku SR, Boman K, Bansal V, Kumar VK, Walkey AJ, Domecq JP, Kashyap R, Aston CE; Society of Critical Care Medicine Discovery Viral Infection and Respiratory Illness Universal Study (VIRUS): COVID-19 Registry Investigator Group. Gupta N, et al. Crit Care Med. 2022 Oct 1;50(10):e744-e758. doi: 10.1097/CCM.0000000000005627. Epub 2022 Jul 27. Crit Care Med. 2022. PMID: 35894609 Free PMC article.
Development of a folate receptor (FR)-targeted indenoisoquinoline using a pH-sensitive N-ethoxybenzylimidazole (NEBI) bifunctional cross-linker.
Cao Y, Yang J. Cao Y, et al. Bioconjug Chem. 2014 May 21;25(5):873-8. doi: 10.1021/bc500146p. Epub 2014 Apr 29. Bioconjug Chem. 2014. PMID: 24758386 Free PMC article.
This Communication describes the synthesis and evaluation of a folate-conjugated drug delivery system (DDS) that incorporates an acid-sensitive N-ethoxybenzylimidazole (NEBI) bifunctional linker and a novel imidazole-containing indenoisoquinoline. ...
This Communication describes the synthesis and evaluation of a folate-conjugated drug delivery system (DDS) that incorporates an acid-sensit …
Loss of ganglioglomerular nerve input to the carotid body impacts the hypoxic ventilatory response in freely-moving rats.
Getsy PM, Coffee GA, Lewis SJ. Getsy PM, et al. Front Physiol. 2023 Mar 16;14:1007043. doi: 10.3389/fphys.2023.1007043. eCollection 2023. Front Physiol. 2023. PMID: 37008015 Free PMC article.
The key findings were that 1) resting ventilatory parameters were similar in SHAM and GGNX rats, 2) the initial changes in frequency of breathing, tidal volume, minute ventilation, inspiratory time, peak inspiratory and expiratory flows, and inspiratory and expiratory drives were …
The key findings were that 1) resting ventilatory parameters were similar in SHAM and GGNX rats, 2) the initial changes in frequency of brea …
Early nebivolol treatment is beneficial in myocardial infarction in rats partly through β3-adrenoceptor remodelling.
Audigane L, Persello A, Piriou N, Ferron M, Trochu JN, Lauzier B, Gauthier C, Rozec B. Audigane L, et al. Clin Exp Pharmacol Physiol. 2021 Jul;48(7):1007-1015. doi: 10.1111/1440-1681.13447. Epub 2020 Dec 14. Clin Exp Pharmacol Physiol. 2021. PMID: 33314348
Isoproterenol response was only altered in MI-V. In MI aorta, Nebi prevented beta(2) - and beta(3) -AR mRNA increases. In addition, Acetylcholine-induced relaxation was lowered in MI-V but preserved with nebivolol. ...
Isoproterenol response was only altered in MI-V. In MI aorta, Nebi prevented beta(2) - and beta(3) -AR mRNA increases. In addition, A …
Metabolic Syndrome and Acute Respiratory Distress Syndrome in Hospitalized Patients With COVID-19.
Denson JL, Gillet AS, Zu Y, Brown M, Pham T, Yoshida Y, Mauvais-Jarvis F, Douglas IS, Moore M, Tea K, Wetherbie A, Stevens R, Lefante J, Shaffer JG, Armaignac DL, Belden KA, Kaufman M, Heavner SF, Danesh VC, Cheruku SR, St Hill CA, Boman K, Deo N, Bansal V, Kumar VK, Walkey AJ, Kashyap R; Society of Critical Care Medicine Discovery Viral Infection and Respiratory Illness Universal Study (VIRUS): COVID-19 Registry Investigator Group. Denson JL, et al. JAMA Netw Open. 2021 Dec 1;4(12):e2140568. doi: 10.1001/jamanetworkopen.2021.40568. JAMA Netw Open. 2021. PMID: 34935924 Free PMC article.
Acidic hydrolysis of N-Ethoxybenzylimidazoles (NEBIs): potential applications as pH-sensitive linkers for drug delivery.
Kong SD, Luong A, Manorek G, Howell SB, Yang J. Kong SD, et al. Bioconjug Chem. 2007 Mar-Apr;18(2):293-6. doi: 10.1021/bc060224s. Epub 2007 Jan 30. Bioconjug Chem. 2007. PMID: 17261055 Free PMC article.
A derivative of NEBI carrying doxorubicin, a widely used anticancer agent, also showed an increased rate of hydrolysis under mild acid compared to that at normal physiological pH. The doxorubicin analogue resulting from hydrolysis from the NEBI exhibited good cytoto …
A derivative of NEBI carrying doxorubicin, a widely used anticancer agent, also showed an increased rate of hydrolysis under mild aci …
Protective Effects of the Third Generation Vasodilatory Βeta - Blocker Nebivolol against D-Galactosamine - Induced Hepatorenal Syndrome in Rats.
Atwa A, Hegazy R, Mohsen R, Yassin N, Kenawy S. Atwa A, et al. Open Access Maced J Med Sci. 2017 Dec 13;5(7):880-892. doi: 10.3889/oamjms.2017.173. eCollection 2017 Dec 15. Open Access Maced J Med Sci. 2017. PMID: 29362613 Free PMC article.
AIM: The present study was constructed to investigate the possible protective effects of nebivolol (Nebi) against D-galactosamine (Gal)-induced HRS in rats. MATERIAL AND METHODS: Rats were treated with Nebi for ten successive days. ...Finally, histopathological exam …
AIM: The present study was constructed to investigate the possible protective effects of nebivolol (Nebi) against D-galactosamine (Ga …
Protective Effects of Vasodilatory Βeta-Blockers Carvedilol and Nebivolol against Glycerol Model of Rhabdomyolysis-Induced Acute Renal Failure in Rats.
Atwa A, Hegazy R, Shaffie N, Yassin N, Kenawy S. Atwa A, et al. Open Access Maced J Med Sci. 2016 Sep 15;4(3):329-336. doi: 10.3889/oamjms.2016.082. Epub 2016 Aug 1. Open Access Maced J Med Sci. 2016. PMID: 27703551 Free PMC article.
They were treated with vehicle, Carv (2.5 mg/kg/day, po) or Nebi (10 mg/kg, po) for 3 successive days starting from an hour prior to Gly injection. ...CONCLUSION: The results clearly demonstrate protective effects of Carv and Nebi against renal damage involved in RM …
They were treated with vehicle, Carv (2.5 mg/kg/day, po) or Nebi (10 mg/kg, po) for 3 successive days starting from an hour prior to …
24 results