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2015 1
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Page 1
Advancements in the use of gene therapy for cardiac arrhythmia.
Murphy NP, Lubbers ER, Mohler PJ. Murphy NP, et al. Heart Rhythm. 2017 Jul;14(7):1061-1062. doi: 10.1016/j.hrthm.2017.03.041. Epub 2017 Apr 4. Heart Rhythm. 2017. PMID: 28385673 Free PMC article. No abstract available.
Impact of stress on cardiac phenotypes in mice harboring an ankyrin-B disease variant.
Wallace MJ, Malhotra N, Mariángelo JIE, Stevens TL, Young LJ, Antwi-Boasiako S, Abdallah D, Takenaka SS, Cavus O, Murphy NP, Han M, Xu X, Mangoni ME, Hund TJ, Roberts JD, Györke S, Mohler PJ, El Refaey M. Wallace MJ, et al. Among authors: murphy np. J Biol Chem. 2023 Jun;299(6):104818. doi: 10.1016/j.jbc.2023.104818. Epub 2023 May 12. J Biol Chem. 2023. PMID: 37182735 Free PMC article.
Inherited Variants in SCARB1 Cause Severe Early-Onset Coronary Artery Disease.
Koenig SN, Sucharski HC, Jose EM, Dudley EK, Madiai F, Cavus O, Argall AD, Williams JL, Murphy NP, Keith CBR, El Refaey M, Gumina RJ, Boudoulas KD, Milks MW, Sofowora G, Smith SA, Hund TJ, Wright NT, Bradley EA, Zareba KM, Wold LE, Mazzaferri EL Jr, Mohler PJ. Koenig SN, et al. Among authors: murphy np. Circ Res. 2021 Jul 9;129(2):296-307. doi: 10.1161/CIRCRESAHA.120.318793. Epub 2021 May 12. Circ Res. 2021. PMID: 33975440 Free PMC article.
Protein Phosphatase 2A Regulates Cardiac Na+ Channels.
El Refaey M, Musa H, Murphy NP, Lubbers ER, Skaf M, Han M, Cavus O, Koenig SN, Wallace MJ, Gratz D, Bradley E, Alsina KM, Wehrens XHT, Hund TJ, Mohler PJ. El Refaey M, et al. Among authors: murphy np. Circ Res. 2019 Mar;124(5):737-746. doi: 10.1161/CIRCRESAHA.118.314350. Circ Res. 2019. PMID: 30602331 Free PMC article.
Altered Expression of Zonula occludens-1 Affects Cardiac Na+ Channels and Increases Susceptibility to Ventricular Arrhythmias.
El Refaey M, Coles S, Musa H, Stevens TL, Wallace MJ, Murphy NP, Antwi-Boasiako S, Young LJ, Manring HR, Curran J, Makara MA, Sas K, Han M, Koenig SN, Skaf M, Kline CF, Janssen PML, Accornero F, Borzok MA, Mohler PJ. El Refaey M, et al. Among authors: murphy np. Cells. 2022 Feb 14;11(4):665. doi: 10.3390/cells11040665. Cells. 2022. PMID: 35203314 Free PMC article.
Defining new mechanistic roles for αII spectrin in cardiac function.
Lubbers ER, Murphy NP, Musa H, Huang CY, Gupta R, Price MV, Han M, Daoud E, Gratz D, El Refaey M, Xu X, Hoeflinger NK, Friel EL, Lancione P, Wallace MJ, Cavus O, Simmons SL, Williams JL, Skaf M, Koenig SN, Janssen PML, Rasband MN, Hund TJ, Mohler PJ. Lubbers ER, et al. Among authors: murphy np. J Biol Chem. 2019 Jun 14;294(24):9576-9591. doi: 10.1074/jbc.RA119.007714. Epub 2019 May 7. J Biol Chem. 2019. PMID: 31064843 Free PMC article.
Common human ANK2 variant confers in vivo arrhythmia phenotypes.
Musa H, Murphy NP, Curran J, Higgins JD, Webb TR, Makara MA, Wright P, Lancione PJ, Lubbers ER, Healy JA, Smith SA, Bennett V, Hund TJ, Kline CF, Mohler PJ. Musa H, et al. Among authors: murphy np. Heart Rhythm. 2016 Sep;13(9):1932-40. doi: 10.1016/j.hrthm.2016.06.012. Epub 2016 Jun 11. Heart Rhythm. 2016. PMID: 27298202
Ankyrin-B dysfunction predisposes to arrhythmogenic cardiomyopathy and is amenable to therapy.
Roberts JD, Murphy NP, Hamilton RM, Lubbers ER, James CA, Kline CF, Gollob MH, Krahn AD, Sturm AC, Musa H, El-Refaey M, Koenig S, Aneq MÅ, Hoorntje ET, Graw SL, Davies RW, Rafiq MA, Koopmann TT, Aafaqi S, Fatah M, Chiasson DA, Taylor MR, Simmons SL, Han M, van Opbergen CJ, Wold LE, Sinagra G, Mittal K, Tichnell C, Murray B, Codima A, Nazer B, Nguyen DT, Marcus FI, Sobriera N, Lodder EM, van den Berg MP, Spears DA, Robinson JF, Ursell PC, Green AK, Skanes AC, Tang AS, Gardner MJ, Hegele RA, van Veen TA, Wilde AA, Healey JS, Janssen PM, Mestroni L, van Tintelen JP, Calkins H, Judge DP, Hund TJ, Scheinman MM, Mohler PJ. Roberts JD, et al. Among authors: murphy np. J Clin Invest. 2019 Jul 2;129(8):3171-3184. doi: 10.1172/JCI125538. eCollection 2019 Jul 2. J Clin Invest. 2019. PMID: 31264976 Free PMC article.
14 results