Retrograde axonal transport of BDNF in retinal ganglion cells is blocked by acute IOP elevation in rats.
Quigley HA, McKinnon SJ, Zack DJ, Pease ME, Kerrigan-Baumrind LA, Kerrigan DF, Mitchell RS.
Quigley HA, et al.
Invest Ophthalmol Vis Sci. 2000 Oct;41(11):3460-6.
Invest Ophthalmol Vis Sci. 2000.
PMID: 11006239
Considering only the radioactivity representing specific retrograde transport of BDNF, IOP elevation to PP25 reduced transport by 74%, whereas elevation to PP0 (equaling systolic blood pressure) reduced specific transport by 83%. CONCLUSIONS: BDNF is transported retrogradely from …
Considering only the radioactivity representing specific retrograde transport of BDNF, IOP elevation to PP25 reduced transport by 74%, where …