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2017 | 1 |
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Page 1
Disruption of Proteostasis by Natural Products and Synthetic Compounds That Induce Pervasive Unfolding of Proteins: Therapeutic Implications.
Pharmaceuticals (Basel). 2023 Apr 19;16(4):616. doi: 10.3390/ph16040616.
Pharmaceuticals (Basel). 2023.
PMID: 37111374
Free PMC article.
Small Molecule Neuropilin-1 Antagonists Combine Antiangiogenic and Antitumor Activity with Immune Modulation through Reduction of Transforming Growth Factor Beta (TGFβ) Production in Regulatory T-Cells.
Powell J, Mota F, Steadman D, Soudy C, Miyauchi JT, Crosby S, Jarvis A, Reisinger T, Winfield N, Evans G, Finniear A, Yelland T, Chou YT, Chan AWE, O'Leary A, Cheng L, Liu D, Fotinou C, Milagre C, Martin JF, Jia H, Frankel P, Djordjevic S, Tsirka SE, Zachary IC, Selwood DL.
Powell J, et al. Among authors: winfield n.
J Med Chem. 2018 May 10;61(9):4135-4154. doi: 10.1021/acs.jmedchem.8b00210. Epub 2018 Apr 24.
J Med Chem. 2018.
PMID: 29648813
Free PMC article.
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Small molecule inhibitors of the neuropilin-1 vascular endothelial growth factor A (VEGF-A) interaction.
Jarvis A, Allerston CK, Jia H, Herzog B, Garza-Garcia A, Winfield N, Ellard K, Aqil R, Lynch R, Chapman C, Hartzoulakis B, Nally J, Stewart M, Cheng L, Menon M, Tickner M, Djordjevic S, Driscoll PC, Zachary I, Selwood DL.
Jarvis A, et al. Among authors: winfield n.
J Med Chem. 2010 Mar 11;53(5):2215-26. doi: 10.1021/jm901755g.
J Med Chem. 2010.
PMID: 20151671
Free PMC article.
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New inhibitor targeting human transcription factor HSF1: effects on the heat shock response and tumor cell survival.
Vilaboa N, Boré A, Martin-Saavedra F, Bayford M, Winfield N, Firth-Clark S, Kirton SB, Voellmy R.
Vilaboa N, et al. Among authors: winfield n.
Nucleic Acids Res. 2017 Jun 2;45(10):5797-5817. doi: 10.1093/nar/gkx194.
Nucleic Acids Res. 2017.
PMID: 28369544
Free PMC article.
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