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Page 1
Unzipping the Secrets of Amyloid Disassembly by the Human Disaggregase.
Cells. 2021 Oct 14;10(10):2745. doi: 10.3390/cells10102745.
Cells. 2021.
PMID: 34685723
Free PMC article.
Review.
The self-association equilibrium of DNAJA2 regulates its interaction with unfolded substrate proteins and with Hsc70.
Velasco-Carneros L, Cuéllar J, Dublang L, Santiago C, Maréchal JD, Martín-Benito J, Maestro M, Fernández-Higuero JÁ, Orozco N, Moro F, Valpuesta JM, Muga A.
Velasco-Carneros L, et al. Among authors: orozco n.
Nat Commun. 2023 Sep 5;14(1):5436. doi: 10.1038/s41467-023-41150-8.
Nat Commun. 2023.
PMID: 37670029
Free PMC article.
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Fine-tuning of the Hsc70-based Human Protein Disaggregase Machinery by the Distinctive C-terminal Extension of Apg2.
Cabrera Y, Bernardo-Seisdedos G, Dublang L, Albesa-Jové D, Orozco N, Viguera AR, Millet O, Muga A, Moro F.
Cabrera Y, et al. Among authors: orozco n.
J Mol Biol. 2022 Nov 30;434(22):167841. doi: 10.1016/j.jmb.2022.167841. Epub 2022 Sep 24.
J Mol Biol. 2022.
PMID: 36167183
Free article.
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All-or-none amyloid disassembly via chaperone-triggered fibril unzipping favors clearance of α-synuclein toxic species.
Franco A, Gracia P, Colom A, Camino JD, Fernández-Higuero JÁ, Orozco N, Dulebo A, Saiz L, Cremades N, Vilar JMG, Prado A, Muga A.
Franco A, et al. Among authors: orozco n.
Proc Natl Acad Sci U S A. 2021 Sep 7;118(36):e2105548118. doi: 10.1073/pnas.2105548118.
Proc Natl Acad Sci U S A. 2021.
PMID: 34462355
Free PMC article.
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Truncation-Driven Lateral Association of α-Synuclein Hinders Amyloid Clearance by the Hsp70-Based Disaggregase.
Franco A, Cuéllar J, Fernández-Higuero JÁ, de la Arada I, Orozco N, Valpuesta JM, Prado A, Muga A.
Franco A, et al. Among authors: orozco n.
Int J Mol Sci. 2021 Nov 30;22(23):12983. doi: 10.3390/ijms222312983.
Int J Mol Sci. 2021.
PMID: 34884786
Free PMC article.
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Author Correction: The self-association equilibrium of DNAJA2 regulates its interaction with unfolded substrate proteins and with Hsc70.
Velasco-Carneros L, Cuéllar J, Dublang L, Santiago C, Maréchal JD, Martín-Benito J, Maestro M, Fernández-Higuero JÁ, Orozco N, Moro F, Valpuesta JM, Muga A.
Velasco-Carneros L, et al. Among authors: orozco n.
Nat Commun. 2024 Jan 2;15(1):99. doi: 10.1038/s41467-023-44499-y.
Nat Commun. 2024.
PMID: 38167402
Free PMC article.
No abstract available.
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Deletion of TAK1 in the myeloid lineage results in the spontaneous development of myelomonocytic leukemia in mice.
Lamothe B, Lai Y, Hur L, Orozco NM, Wang J, Campos AD, Xie M, Schneider MD, Lockworth CR, Jakacky J, Tran D, Ho M, Dawud S, Dong C, Lin HK, Hu P, Estrov Z, Bueso-Ramos CE, Darnay BG.
Lamothe B, et al. Among authors: orozco nm.
PLoS One. 2012;7(12):e51228. doi: 10.1371/journal.pone.0051228. Epub 2012 Dec 10.
PLoS One. 2012.
PMID: 23251462
Free PMC article.
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