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Page 1
N1-methylation of adenosine (m1A) in ND5 mRNA leads to complex I dysfunction in Alzheimer's disease.
Jörg M, Plehn JE, Kristen M, Lander M, Walz L, Lietz C, Wijns J, Pichot F, Rojas-Charry L, Wirtz Martin KM, Ruffini N, Kreim N, Gerber S, Motorin Y, Endres K, Rossmanith W, Methner A, Helm M, Friedland K. Jörg M, et al. Among authors: kreim n. Mol Psychiatry. 2024 Jan 29. doi: 10.1038/s41380-024-02421-y. Online ahead of print. Mol Psychiatry. 2024. PMID: 38287100
p38-MK2 signaling axis regulates RNA metabolism after UV-light-induced DNA damage.
Borisova ME, Voigt A, Tollenaere MAX, Sahu SK, Juretschke T, Kreim N, Mailand N, Choudhary C, Bekker-Jensen S, Akutsu M, Wagner SA, Beli P. Borisova ME, et al. Among authors: kreim n. Nat Commun. 2018 Mar 9;9(1):1017. doi: 10.1038/s41467-018-03417-3. Nat Commun. 2018. PMID: 29523821 Free PMC article.
Hakai is required for stabilization of core components of the m6A mRNA methylation machinery.
Bawankar P, Lence T, Paolantoni C, Haussmann IU, Kazlauskiene M, Jacob D, Heidelberger JB, Richter FM, Nallasivan MP, Morin V, Kreim N, Beli P, Helm M, Jinek M, Soller M, Roignant JY. Bawankar P, et al. Among authors: kreim n. Nat Commun. 2021 Jun 18;12(1):3778. doi: 10.1038/s41467-021-23892-5. Nat Commun. 2021. PMID: 34145251 Free PMC article.
m6A modulates neuronal functions and sex determination in Drosophila.
Lence T, Akhtar J, Bayer M, Schmid K, Spindler L, Ho CH, Kreim N, Andrade-Navarro MA, Poeck B, Helm M, Roignant JY. Lence T, et al. Among authors: kreim n. Nature. 2016 Dec 8;540(7632):242-247. doi: 10.1038/nature20568. Epub 2016 Nov 30. Nature. 2016. PMID: 27919077
Zc3h13/Flacc is required for adenosine methylation by bridging the mRNA-binding factor Rbm15/Spenito to the m6A machinery component Wtap/Fl(2)d.
Knuckles P, Lence T, Haussmann IU, Jacob D, Kreim N, Carl SH, Masiello I, Hares T, Villaseñor R, Hess D, Andrade-Navarro MA, Biggiogera M, Helm M, Soller M, Bühler M, Roignant JY. Knuckles P, et al. Among authors: kreim n. Genes Dev. 2018 Mar 1;32(5-6):415-429. doi: 10.1101/gad.309146.117. Epub 2018 Mar 13. Genes Dev. 2018. PMID: 29535189 Free PMC article.
11 results