Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1950 1
1952 2
1953 1
1955 5
1956 3
1957 3
1958 1
1959 3
1960 1
1962 1
1963 1
1964 1
1966 1
1969 1
1971 4
1973 1
1974 2
1975 2
1976 1
1977 1
1978 2
1980 1
1982 2
1984 2
1985 5
1986 6
1988 3
1989 5
1990 2
1991 5
1992 6
1993 1
1994 2
1996 2
1997 1
1998 6
1999 4
2000 5
2001 3
2002 3
2003 3
2004 6
2005 2
2006 4
2007 10
2008 17
2009 14
2010 19
2011 20
2012 16
2013 26
2014 26
2015 44
2016 20
2017 35
2018 48
2019 64
2020 51
2021 60
2022 56
2023 59
2024 18

Text availability

Article attribute

Article type

Publication date

Search Results

643 results

Results by year

Filters applied: . Clear all
The following term was not found in PubMed: Zabuta
Page 1
Pathogenicity and virulence of Clostridium perfringens.
Mehdizadeh Gohari I, A Navarro M, Li J, Shrestha A, Uzal F, A McClane B. Mehdizadeh Gohari I, et al. Virulence. 2021 Dec;12(1):723-753. doi: 10.1080/21505594.2021.1886777. Virulence. 2021. PMID: 33843463 Free PMC article.
These factors can promote toxin action in vitro and, perhaps in vivo, and also enhance C. perfringens intestinal colonization, e.g. NanI sialidase increases C. perfringens adherence to intestinal tissue and generates nutrients for its growth, at least in vitro. ...
These factors can promote toxin action in vitro and, perhaps in vivo, and also enhance C. perfringens intestinal colonization, e.g. NanI …
NanI Sialidase Enhances the Action of Clostridium perfringens Enterotoxin in the Presence of Mucus.
Navarro MA, Li J, Beingesser J, McClane BA, Uzal FA. Navarro MA, et al. mSphere. 2021 Dec 22;6(6):e0084821. doi: 10.1128/mSphere.00848-21. Epub 2021 Dec 15. mSphere. 2021. PMID: 34908460 Free PMC article.
However, the copresence of purified NanI resulted in significant CPE-induced lethality. More CPE was detected in the sera of mice challenged with 50 mug/mL of CPE when NanI was copresent during challenge. ...IMPORTANCE NanI is a sialidase produced by some Clo …
However, the copresence of purified NanI resulted in significant CPE-induced lethality. More CPE was detected in the sera of mice cha …
NanR Regulates nanI Sialidase Expression by Clostridium perfringens F4969, a Human Enteropathogenic Strain.
Li J, Evans DR, Freedman JC, McClane BA. Li J, et al. Infect Immun. 2017 Aug 18;85(9):e00241-17. doi: 10.1128/IAI.00241-17. Print 2017 Sep. Infect Immun. 2017. PMID: 28652312 Free PMC article.
In contrast, low glucose concentrations did not affect exosialidase activity or nanI transcription. However, either high Neu5Ac or high glucose concentrations repressed F4969 culture supernatant sialidase activity and nanI transcription levels. ...To begin to evalua …
In contrast, low glucose concentrations did not affect exosialidase activity or nanI transcription. However, either high Neu5Ac or hi …
NanI Sialidase Is an Important Contributor to Clostridium perfringens Type F Strain F4969 Intestinal Colonization in Mice.
Navarro MA, Li J, McClane BA, Morrell E, Beingesser J, Uzal FA. Navarro MA, et al. Infect Immun. 2018 Nov 20;86(12):e00462-18. doi: 10.1128/IAI.00462-18. Print 2018 Dec. Infect Immun. 2018. PMID: 30297524 Free PMC article.
When clindamycin-pretreated mice were challenged by oral gavage with equivalent numbers of F4969 bacteria or its isogenic nanI null mutant, significantly lower numbers of the nanI mutant were recovered from all intestinal segments, and it was completely cleared from …
When clindamycin-pretreated mice were challenged by oral gavage with equivalent numbers of F4969 bacteria or its isogenic nanI null m …
The NanI and NanJ sialidases of Clostridium perfringens are not essential for virulence.
Chiarezza M, Lyras D, Pidot SJ, Flores-Díaz M, Awad MM, Kennedy CL, Cordner LM, Phumoonna T, Poon R, Hughes ML, Emmins JJ, Alape-Girón A, Rood JI. Chiarezza M, et al. Infect Immun. 2009 Oct;77(10):4421-8. doi: 10.1128/IAI.00548-09. Epub 2009 Aug 3. Infect Immun. 2009. PMID: 19651873 Free PMC article.
C. perfringens strains have combinations of three different sialidase genes, two of which, nanI and nanJ, encode secreted sialidases. The nanI and nanJ genes were insertionally inactivated by homologous recombination in derivatives of sequenced strain 13 and were sh …
C. perfringens strains have combinations of three different sialidase genes, two of which, nanI and nanJ, encode secreted sialidases. …
NanI Sialidase Contributes to the Growth and Adherence of Clostridium perfringens Type F Strain F4969 in the Presence of Adherent Mucus.
Li J, Navarro MA, Uzal FA, McClane BA. Li J, et al. Infect Immun. 2021 Oct 15;89(11):e0025621. doi: 10.1128/IAI.00256-21. Epub 2021 Aug 16. Infect Immun. 2021. PMID: 34424746 Free PMC article.
Demonstrating the specific importance of NanI for this effect, type F NFD strain F4969 or a complementing strain grew and adhered better than an isogenic nanI null mutant in the presence of HT29-MTX-E12 cells versus HT29 cells. ...By demonstrating a growth and adher …
Demonstrating the specific importance of NanI for this effect, type F NFD strain F4969 or a complementing strain grew and adhered bet …
NanI Sialidase, CcpA, and CodY Work Together To Regulate Epsilon Toxin Production by Clostridium perfringens Type D Strain CN3718.
Li J, Freedman JC, McClane BA. Li J, et al. J Bacteriol. 2015 Oct;197(20):3339-53. doi: 10.1128/JB.00349-15. Epub 2015 Aug 10. J Bacteriol. 2015. PMID: 26260460 Free PMC article.
The current study proved that the lower ETX production by strain BMC202 is due to nanI gene disruption, since both genetic and physical (NanI or sialic acid) complementation increased ETX production by BMC202. Furthermore, a sialidase inhibitor that interfered with …
The current study proved that the lower ETX production by strain BMC202 is due to nanI gene disruption, since both genetic and physic …
Oxygen consumption.
Agostoni PG, Bussotti M, Nani F, Pontone G, Conca C, Melzi G, Morgagni F, Palermo P, Guazzi M. Agostoni PG, et al. Cardiologia. 1999 Nov;44(11):987-92. Cardiologia. 1999. PMID: 10686774 Review.
643 results