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CD28 Superagonistic Activation of T Cells Induces a Tumor Cell-Like Metabolic Program.
Thaventhiran T, Wong W, Alghanem AF, Alhumeed N, Aljasir MA, Ramsey S, Sethu S, Yeang HXA, Chadwick AE, Cross M, Webb SD, Djouhri L, Ball C, Stebbings R, Sathish JG. Thaventhiran T, et al. Among authors: alhumeed n. Monoclon Antib Immunodiagn Immunother. 2019 Apr;38(2):60-69. doi: 10.1089/mab.2018.0042. Monoclon Antib Immunodiagn Immunother. 2019. PMID: 31009338 Free PMC article.
Failure to upregulate cell surface PD-1 is associated with dysregulated stimulation of T cells by TGN1412-like CD28 superagonist.
Thaventhiran T, Alhumeed N, Yeang HX, Sethu S, Downey JS, Alghanem AF, Olayanju A, Smith EL, Cross MJ, Webb SD, Williams DP, Bristow A, Ball C, Stebbings R, Sathish JG. Thaventhiran T, et al. Among authors: alhumeed n. MAbs. 2014;6(5):1290-9. doi: 10.4161/mabs.29758. Epub 2014 Oct 30. MAbs. 2014. PMID: 25517314 Free PMC article.
Nuclear factor-erythroid 2 (NF-E2) p45-related factor-2 (Nrf2) modulates dendritic cell immune function through regulation of p38 MAPK-cAMP-responsive element binding protein/activating transcription factor 1 signaling.
Al-Huseini LM, Aw Yeang HX, Sethu S, Alhumeed N, Hamdam JM, Tingle Y, Djouhri L, Kitteringham N, Park BK, Goldring CE, Sathish JG. Al-Huseini LM, et al. Among authors: alhumeed n. J Biol Chem. 2013 Aug 2;288(31):22281-8. doi: 10.1074/jbc.M113.483420. Epub 2013 Jun 17. J Biol Chem. 2013. PMID: 23775080 Free PMC article.