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Page 1
Mitochondrial DNA repair in aging and disease.
Druzhyna NM, Wilson GL, LeDoux SP. Druzhyna NM, et al. Mech Ageing Dev. 2008 Jul-Aug;129(7-8):383-90. doi: 10.1016/j.mad.2008.03.002. Epub 2008 Mar 13. Mech Ageing Dev. 2008. PMID: 18417187 Free PMC article. Review.
Upregulation of Cystathionine-β-Synthase in Colonic Epithelia Reprograms Metabolism and Promotes Carcinogenesis.
Phillips CM, Zatarain JR, Nicholls ME, Porter C, Widen SG, Thanki K, Johnson P, Jawad MU, Moyer MP, Randall JW, Hellmich JL, Maskey M, Qiu S, Wood TG, Druzhyna N, Szczesny B, Módis K, Szabo C, Chao C, Hellmich MR. Phillips CM, et al. Among authors: druzhyna n. Cancer Res. 2017 Nov 1;77(21):5741-5754. doi: 10.1158/0008-5472.CAN-16-3480. Epub 2017 Sep 18. Cancer Res. 2017. PMID: 28923859 Free PMC article.
Efficacy of Novel Aminooxyacetic Acid Prodrugs in Colon Cancer Models: Towards Clinical Translation of the Cystathionine β-Synthase Inhibition Concept.
Hellmich MR, Chao C, Módis K, Ding Y, Zatarain JR, Thanki K, Maskey M, Druzhyna N, Untereiner AA, Ahmad A, Xue Y, Chen H, Russell WK, Wang J, Zhou J, Szabo C. Hellmich MR, et al. Among authors: druzhyna n. Biomolecules. 2021 Jul 21;11(8):1073. doi: 10.3390/biom11081073. Biomolecules. 2021. PMID: 34439739 Free PMC article.
The PARP inhibitor olaparib exerts beneficial effects in mice subjected to cecal ligature and puncture and in cells subjected to oxidative stress without impairing DNA integrity: A potential opportunity for repurposing a clinically used oncological drug for the experimental therapy of sepsis.
Ahmad A, Vieira JC, de Mello AH, de Lima TM, Ariga SK, Barbeiro DF, Barbeiro HV, Szczesny B, Törö G, Druzhyna N, Randi EB, Marcatti M, Toliver-Kinsky T, Kiss A, Liaudet L, Salomao R, Soriano FG, Szabo C. Ahmad A, et al. Among authors: druzhyna n. Pharmacol Res. 2019 Jul;145:104263. doi: 10.1016/j.phrs.2019.104263. Epub 2019 May 6. Pharmacol Res. 2019. PMID: 31071432 Free PMC article.
17 results