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A benzodiazepine activator locks Kv7.1 channels open by electro-mechanical uncoupling.
Schreiber JA, Möller M, Zaydman M, Zhao L, Beller Z, Becker S, Ritter N, Hou P, Shi J, Silva J, Wrobel E, Strutz-Seebohm N, Decher N, Schmitt N, Meuth SG, Düfer M, Wünsch B, Cui J, Seebohm G. Schreiber JA, et al. Among authors: ritter n. Commun Biol. 2022 Apr 1;5(1):301. doi: 10.1038/s42003-022-03229-8. Commun Biol. 2022. PMID: 35365746 Free PMC article.
Synthesis of tropane-based σ1 receptor antagonists with antiallodynic activity.
Bechthold E, Schreiber JA, Ritter N, Grey L, Schepmann D, Daniliuc C, González-Cano R, Nieto FR, Seebohm G, Wünsch B. Bechthold E, et al. Among authors: ritter n. Eur J Med Chem. 2022 Feb 15;230:114113. doi: 10.1016/j.ejmech.2022.114113. Epub 2022 Jan 13. Eur J Med Chem. 2022. PMID: 35065412
Downstream Allosteric Modulation of NMDA Receptors by 3-Benzazepine Derivatives.
Ritter N, Disse P, Aymanns I, Mücher L, Schreiber JA, Brenker C, Strünker T, Schepmann D, Budde T, Strutz-Seebohm N, Ametamey SM, Wünsch B, Seebohm G. Ritter N, et al. Mol Neurobiol. 2023 Dec;60(12):7238-7252. doi: 10.1007/s12035-023-03526-1. Epub 2023 Aug 5. Mol Neurobiol. 2023. PMID: 37542648 Free PMC article.
A novel NMDA receptor test model based on hiPSC-derived neural cells.
Disse P, Aymanns I, Ritter N, Peischard S, Korn L, Wiendl H, Pawlowski M, Kovac S, Meuth SG, Budde T, Strutz-Seebohm N, Wünsch B, Seebohm G. Disse P, et al. Among authors: ritter n. Biol Chem. 2023 Jan 12;404(4):267-277. doi: 10.1515/hsz-2022-0216. Print 2023 Mar 28. Biol Chem. 2023. PMID: 36630596
Activation of non-classical NMDA receptors by glycine impairs barrier function of brain endothelial cells.
Epping L, Schroeter CB, Nelke C, Bock S, Gola L, Ritter N, Herrmann AM, Räuber S, Henes A, Wasser B, Fernandez-Orth J, Neuhaus W, Bittner S, Budde T, Platten M, Kovac S, Seebohm G, Ruck T, Cerina M, Meuth SG. Epping L, et al. Among authors: ritter n. Cell Mol Life Sci. 2022 Aug 11;79(9):479. doi: 10.1007/s00018-022-04502-z. Cell Mol Life Sci. 2022. PMID: 35951110 Free PMC article.
The second PI(3,5)P2 binding site in the S0 helix of KCNQ1 stabilizes PIP2-at the primary PI1 site with potential consequences on intermediate-to-open state transition.
Dellin M, Rohrbeck I, Asrani P, Schreiber JA, Ritter N, Glorius F, Wünsch B, Budde T, Temme L, Strünker T, Stallmeyer B, Tüttelmann F, Meuth SG, Spehr M, Matschke J, Steinbicker A, Gatsogiannis C, Stoll R, Strutz-Seebohm N, Seebohm G. Dellin M, et al. Among authors: ritter n. Biol Chem. 2023 Feb 23;404(4):241-254. doi: 10.1515/hsz-2022-0247. Print 2023 Mar 28. Biol Chem. 2023. PMID: 36809224
14 results