Synthesis of some new Thieno[2,3-b]pyridines, Pyrimidino[4',5':4,5]thieno[2,3-b]pyridine and Pyridines Incorporating 5-Bromobenzofuran-2-yl Moiety

Nadia Abdelhamed Abdelriheem; Sayed Abdel-Kader Ahmad; Abdou Osman Abdelhamid

doi:10.3390/molecules20010822

Synthesis of some new Thieno[2,3-b]pyridines, Pyrimidino[4',5':4,5]thieno[2,3-b]pyridine and Pyridines Incorporating 5-Bromobenzofuran-2-yl Moiety

Molecules. 2015 Jan 7;20(1):822-38. doi: 10.3390/molecules20010822.

Authors

Nadia Abdelhamed Abdelriheem¹, Sayed Abdel-Kader Ahmad², Abdou Osman Abdelhamid³

Affiliations

¹ Department of Chemistry, Faculty of Science, Cairo University, Giza 12613, Egypt. nadia.abdelhamid5@gmail.com.
² Department of Chemistry, Faculty of Science, Beni-Suef University, Beni-Suef 62514, Egypt.
³ Department of Chemistry, Faculty of Science, Cairo University, Giza 12613, Egypt. Abdelhamid45@gmail.com.

Abstract

2-Sulfanyl-6-(2-thienyl)pyridine-3-carbonitrile, 1-Amino-6-(5-bromo-benzofuran-2-yl)-2-oxo-1,2-dihydro-pyridine-3-carbonitrile, thieno[2,3-b]pyridins, pyrimidino[4',5':4,5] thieno[2,3-b]pyridine, quinazoline and carbamate derivatives were synthesized from sodium 3-(5-bromobenzofuran-2-yl)-3-oxoprop-1-en-1-olate with. The newly synthesized compounds were elucidated by elemental analysis, spectral data, and alternative synthesis whenever possible and chemical transportation.

MeSH terms

Furans / chemistry*
Mass Spectrometry
Pyridines / chemical synthesis*
Pyridines / chemistry
Spectrophotometry, Infrared

Substances

Furans
Pyridines