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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1916 1
1974 1
1975 1
1976 1
1978 1
1979 3
1980 2
1982 1
1983 1
1984 3
1985 1
1986 2
1987 6
1988 2
1989 1
1990 4
1991 4
1992 7
1993 6
1994 13
1995 8
1996 7
1997 21
1998 13
1999 9
2000 16
2001 18
2002 16
2003 14
2004 13
2005 42
2006 41
2007 46
2008 44
2009 55
2010 63
2011 45
2012 63
2013 59
2014 84
2015 81
2016 83
2017 66
2018 100
2019 96
2020 105
2021 125
2022 113
2023 99
2024 47

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1,450 results

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Page 1
Consensus statement: Academy of Nutrition and Dietetics and American Society for Parenteral and Enteral Nutrition: characteristics recommended for the identification and documentation of adult malnutrition (undernutrition).
White JV, Guenter P, Jensen G, Malone A, Schofield M; Academy Malnutrition Work Group; A.S.P.E.N. Malnutrition Task Force; A.S.P.E.N. Board of Directors. White JV, et al. JPEN J Parenter Enteral Nutr. 2012 May;36(3):275-83. doi: 10.1177/0148607112440285. JPEN J Parenter Enteral Nutr. 2012. PMID: 22535923
The Academy of Nutrition and Dietetics (Academy) and the American Society for Parenteral and Enteral Nutrition (A.S.P.E.N.) recommend that a standardized set of diagnostic characteristics be used to identify and document adult malnutrition in routine clinical practice. ...
The Academy of Nutrition and Dietetics (Academy) and the American Society for Parenteral and Enteral Nutrition (A.S.P.E.N.) recommend …
2-Oxoglutarate-Dependent Oxygenases.
Islam MS, Leissing TM, Chowdhury R, Hopkinson RJ, Schofield CJ. Islam MS, et al. Annu Rev Biochem. 2018 Jun 20;87:585-620. doi: 10.1146/annurev-biochem-061516-044724. Epub 2018 Mar 1. Annu Rev Biochem. 2018. PMID: 29494239 Review.
2-Oxoglutarate (2OG)-dependent oxygenases (2OGXs) catalyze a remarkably diverse range of oxidative reactions. In animals, these comprise hydroxylations and N-demethylations proceeding via hydroxylation; in plants and microbes, they catalyze a wider range including ring for …
2-Oxoglutarate (2OG)-dependent oxygenases (2OGXs) catalyze a remarkably diverse range of oxidative reactions. In animals, these comprise hyd …
Impact of enhanced metabolic stability on pharmacokinetics and pharmacodynamics of GalNAc-siRNA conjugates.
Nair JK, Attarwala H, Sehgal A, Wang Q, Aluri K, Zhang X, Gao M, Liu J, Indrakanti R, Schofield S, Kretschmer P, Brown CR, Gupta S, Willoughby JLS, Boshar JA, Jadhav V, Charisse K, Zimmermann T, Fitzgerald K, Manoharan M, Rajeev KG, Akinc A, Hutabarat R, Maier MA. Nair JK, et al. Nucleic Acids Res. 2017 Nov 2;45(19):10969-10977. doi: 10.1093/nar/gkx818. Nucleic Acids Res. 2017. PMID: 28981809 Free PMC article.
Covalent attachment of a synthetic triantennary N-acetylagalactosamine (GalNAc) ligand to chemically modified siRNA has enabled asialoglycoprotein (ASGPR)-mediated targeted delivery of therapeutically active siRNAs to hepatocytes in vivo. ...
Covalent attachment of a synthetic triantennary N-acetylagalactosamine (GalNAc) ligand to chemically modified siRNA has enabled asial …
On the robustness of N-mixture models.
Link WA, Schofield MR, Barker RJ, Sauer JR. Link WA, et al. Ecology. 2018 Jul;99(7):1547-1551. doi: 10.1002/ecy.2362. Epub 2018 Jun 6. Ecology. 2018. PMID: 29702727
N-mixture models provide an appealing alternative to mark-recapture models, in that they allow for estimation of detection probability and population size from count data, without requiring that individual animals be identified. There is, however, a cost to using the N …
N-mixture models provide an appealing alternative to mark-recapture models, in that they allow for estimation of detection probabilit …
Roles of 2-oxoglutarate oxygenases and isopenicillin N synthase in beta-lactam biosynthesis.
Rabe P, Kamps JJAG, Schofield CJ, Lohans CT. Rabe P, et al. Nat Prod Rep. 2018 Aug 15;35(8):735-756. doi: 10.1039/c8np00002f. Nat Prod Rep. 2018. PMID: 29808887 Free PMC article. Review.
Covering: up to 2017 2-Oxoglutarate (2OG) dependent oxygenases and the homologous oxidase isopenicillin N synthase (IPNS) play crucial roles in the biosynthesis of beta-lactam ring containing natural products. ...
Covering: up to 2017 2-Oxoglutarate (2OG) dependent oxygenases and the homologous oxidase isopenicillin N synthase (IPNS) play crucia …
Structural Basis of Metallo-beta-lactamase Inhibition by N-Sulfamoylpyrrole-2-carboxylates.
Farley AJM, Ermolovich Y, Calvopiña K, Rabe P, Panduwawala T, Brem J, Björkling F, Schofield CJ. Farley AJM, et al. ACS Infect Dis. 2021 Jun 11;7(6):1809-1817. doi: 10.1021/acsinfecdis.1c00104. Epub 2021 May 18. ACS Infect Dis. 2021. PMID: 34003651 Free PMC article.
., clavulanic acid, avibactam) are established for clinical use, no such MBL inhibitors are available. We report on the synthesis and mechanism of inhibition of N-sulfamoylpyrrole-2-carboxylates (NSPCs) which are potent inhibitors of clinically relevant B1 subclass MBLs, i …
., clavulanic acid, avibactam) are established for clinical use, no such MBL inhibitors are available. We report on the synthesis and mechan …
Recent Progress in Histone Demethylase Inhibitors.
McAllister TE, England KS, Hopkinson RJ, Brennan PE, Kawamura A, Schofield CJ. McAllister TE, et al. J Med Chem. 2016 Feb 25;59(4):1308-29. doi: 10.1021/acs.jmedchem.5b01758. Epub 2016 Feb 2. J Med Chem. 2016. PMID: 26710088 Review.
There is increasing interest in targeting histone N-methyl-lysine demethylases (KDMs) with small molecules both for the generation of probes for target exploration and for therapeutic purposes. Here we update on previous reviews on the inhibition of the lysine-specific dem …
There is increasing interest in targeting histone N-methyl-lysine demethylases (KDMs) with small molecules both for the generation of …
On the reliability of N-mixture models for count data.
Barker RJ, Schofield MR, Link WA, Sauer JR. Barker RJ, et al. Biometrics. 2018 Mar;74(1):369-377. doi: 10.1111/biom.12734. Epub 2017 Jul 3. Biometrics. 2018. PMID: 28672424
N-mixture models describe count data replicated in time and across sites in terms of abundance N and detectability p. They are popular because they allow inference about N while controlling for factors that influence p without the need for marking animals. .. …
N-mixture models describe count data replicated in time and across sites in terms of abundance N and detectability p. They are …
Oxygenase-catalyzed desymmetrization of N,N-dialkyl-piperidine-4-carboxylic acids.
Rydzik AM, Leung IK, Kochan GT, McDonough MA, Claridge TD, Schofield CJ. Rydzik AM, et al. Angew Chem Int Ed Engl. 2014 Oct 6;53(41):10925-7. doi: 10.1002/anie.201406125. Epub 2014 Aug 27. Angew Chem Int Ed Engl. 2014. PMID: 25164544 Free PMC article.
BBOX was shown to catalyze the oxidative desymmetrization of achiral N,N-dialkyl piperidine-4-carboxylates to give products with two or three stereogenic centers....
BBOX was shown to catalyze the oxidative desymmetrization of achiral N,N-dialkyl piperidine-4-carboxylates to give products wi …
Human carnitine biosynthesis proceeds via (2S,3S)-3-hydroxy-N(epsilon)-trimethyllysine.
Leśniak RK, Markolovic S, Tars K, Schofield CJ. Leśniak RK, et al. Chem Commun (Camb). 2016 Dec 22;53(2):440-442. doi: 10.1039/c6cc08381a. Chem Commun (Camb). 2016. PMID: 27965989 Free PMC article.
The stereochemistry of the 3-hydroxy-N(epsilon)-trimethyllysine product of TMLH has not been defined. We report enzymatic and asymmetric synthetic studies, which define the product of TMLH catalysis as (2S,3S)-3-hydroxy-N(epsilon)-trimethyllysine....
The stereochemistry of the 3-hydroxy-N(epsilon)-trimethyllysine product of TMLH has not been defined. We report enzymatic and asymmet …
1,450 results