Whole-genome comparison of disease and carriage strains provides insights into virulence evolution in Neisseria meningitidis.
Schoen C, Blom J, Claus H, Schramm-Glück A, Brandt P, Müller T, Goesmann A, Joseph B, Konietzny S, Kurzai O, Schmitt C, Friedrich T, Linke B, Vogel U, Frosch M.
Schoen C, et al.
Proc Natl Acad Sci U S A. 2008 Mar 4;105(9):3473-8. doi: 10.1073/pnas.0800151105. Epub 2008 Feb 27.
Proc Natl Acad Sci U S A. 2008.
PMID: 18305155
Free PMC article.
The expression of a polysaccharide capsule is the only trait that has been convincingly linked to the pathogenic potential of N. meningitidis. To gain insight into the evolution of virulence traits in this species, whole-genome sequences of three meningococcal carriage iso …
The expression of a polysaccharide capsule is the only trait that has been convincingly linked to the pathogenic potential of N. meni …